A Microfluidic Chip for Screening and Sequencing of Monoclonal Antibody at a Single-Cell Level

2021 ◽  
Author(s):  
Weikai Zhang ◽  
Qin Li ◽  
Fei Jia ◽  
Zhiyuan Hu ◽  
Zewen Wei
Keyword(s):  
Monoclonal Antibody ◽  
Single Cell ◽  
Microfluidic Chip ◽  
Single Cell Level ◽  
Cell Level

A microfluidic chip for screening high-producing hybridomas at single cell level

Lab on a Chip ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 4043-4051
Author(s):  
Weikai Zhang ◽  
Ren Li ◽  
Fei Jia ◽  
Zhiyuan Hu ◽  
Qin Li ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Targeted Therapy ◽  
Single Cell ◽  
Laboratory Study ◽  
Microfluidic Chip ◽  
Single Cell Level ◽  
Cell Level ◽  
Biomedical Study

Hybridomas are a commonly used, or even the only option, for laboratory study and pilot production of monoclonal antibodies (mAbs), which are crucial for both targeted therapy and biomedical study.

scholarly journals Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Ren Li ◽  
Mingxing Zhou ◽  
Jine Li ◽  
Zihua Wang ◽  
Weikai Zhang ◽  
...  
Keyword(s):  
Single Cell ◽  
Microfluidic Chip ◽  
Single Cell Level ◽  
Cell Level
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