Two-Photon Fluorescence Probe for Selective Monitoring of Superoxide in Live Cells and Tissues

2019 ◽  
Vol 91 (22) ◽  
pp. 14691-14696 ◽  
Author(s):  
Liyan Chen ◽  
Myoung Ki Cho ◽  
Di Wu ◽  
Hwan Myung Kim ◽  
Juyoung Yoon
2017 ◽  
Vol 70 (6) ◽  
pp. 705
Author(s):  
Chibao Huang ◽  
Daohai Zhang ◽  
Junle Qu ◽  
Xiaonan Liu ◽  
Guanglian Zhao ◽  
...  

A novel two-photon fluorescence probe for Hg2+ derived from bis(styryl)terephthalonitrile, as a two-photon fluorophore, and bis[2-(2-hydroxyethyl sulfanyl) ethyl]amino group (ionophore), as a novel Hg2+ ligand, was developed. The probe possesses small molecule size, large two-photon absorption cross-section (1067 GM) in H2O, non-cytotoxic effect, long wavelength emission at 588 nm, large Stokes shift (121 nm), excellent photostability, high water solubility, good cell permeability, and pH insensitivity in the biologically relevant range. The probe can selectively detect Hg2+ ions in live cells and living tissues without interference from other metal ions and the membrane-bound probes, and its quenching constant is 8.73 × 105 M–1.


2016 ◽  
Vol 15 (3) ◽  
pp. 412-419 ◽  
Author(s):  
Xinyue Zhu ◽  
Yan Li ◽  
Wenyan Zan ◽  
Jianjian Zhang ◽  
Zhenjie Chen ◽  
...  

An effective off-on two-photon fluorescence imaging probe for thiols was developed and successfully applied to image thiols both in live cells and tissues.


2020 ◽  
Vol 56 (27) ◽  
pp. 3871-3874
Author(s):  
Jian Chen ◽  
Chenwen Shao ◽  
Xueao Wang ◽  
Jin Gu ◽  
Hai-Liang Zhu ◽  
...  

A two-photon (TP) fluorescence probe has been developed for imaging endogenous FA fluxes during metabolic and epigenetic processes in animal models, especially in live brains.


Small ◽  
2019 ◽  
Vol 15 (48) ◽  
pp. 1901673 ◽  
Author(s):  
Xiaoxue Ye ◽  
Yunhui Xiang ◽  
Qirong Wang ◽  
Zhen Li ◽  
Zhihong Liu

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