Conventional and Alternative Aviation Fuels: Occupational Exposure and Health Effects

2021 ◽  
Author(s):  
Nektarios Karanikas ◽  
Cherry Foster ◽  
Adolfo Beltran Hernandez ◽  
Alice Harvey ◽  
Ozan Targal ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
Health Effects ◽  
Alternative Aviation Fuels

scholarly journals Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression

2019 ◽  
Vol 28 (15) ◽  
pp. 2477-2485 ◽  
Author(s):  
Diana A van der Plaat ◽  
Judith M Vonk ◽  
Natalie Terzikhan ◽  
Kim de Jong ◽  
Maaike de Vries ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Occupational Exposure ◽  
Health Effects ◽  
Mineral Dust ◽  
Occupational Exposures ◽  
Expression Levels ◽  
Adverse Health Effects ◽  
Never Smokers ◽  
Gene Expression Levels

Abstract Many workers are daily exposed to occupational agents like gases/fumes, mineral dust or biological dust, which could induce adverse health effects. Epigenetic mechanisms, such as DNA methylation, have been suggested to play a role. We therefore aimed to identify differentially methylated regions (DMRs) upon occupational exposures in never-smokers and investigated if these DMRs associated with gene expression levels. To determine the effects of occupational exposures independent of smoking, 903 never-smokers of the LifeLines cohort study were included. We performed three genome-wide methylation analyses (Illumina 450 K), one per occupational exposure being gases/fumes, mineral dust and biological dust, using robust linear regression adjusted for appropriate confounders. DMRs were identified using comb-p in Python. Results were validated in the Rotterdam Study (233 never-smokers) and methylation-expression associations were assessed using Biobank-based Integrative Omics Study data (n = 2802). Of the total 21 significant DMRs, 14 DMRs were associated with gases/fumes and 7 with mineral dust. Three of these DMRs were associated with both exposures (RPLP1 and LINC02169 (2×)) and 11 DMRs were located within transcript start sites of gene expression regulating genes. We replicated two DMRs with gases/fumes (VTRNA2-1 and GNAS) and one with mineral dust (CCDC144NL). In addition, nine gases/fumes DMRs and six mineral dust DMRs significantly associated with gene expression levels. Our data suggest that occupational exposures may induce differential methylation of gene expression regulating genes and thereby may induce adverse health effects. Given the millions of workers that are exposed daily to occupational exposures, further studies on this epigenetic mechanism and health outcomes are warranted.

Occupational exposure to pesticides and associated health effects among greenhouse farm workers

2020 ◽  
Vol 27 (18) ◽  
pp. 22251-22270
Author(s):  
Patrick Amoatey ◽  
Ahmed Al-Mayahi ◽  
Hamid Omidvarborna ◽  
Mahad Said Baawain ◽  
Hameed Sulaiman
Keyword(s):  
Occupational Exposure ◽  
Health Effects ◽  
Farm Workers

Occupational exposure to solid chemical agents in biomass-fired power plants and associated health effects

Chemosphere ◽  
2014 ◽  
Vol 104 ◽  
pp. 25-31 ◽  
Author(s):  
M. Jumpponen ◽  
H. Rönkkömäki ◽  
P. Pasanen ◽  
J. Laitinen
Keyword(s):  
Occupational Exposure ◽  
Health Effects ◽  
Power Plants ◽  
Chemical Agents

scholarly journals 715 Occupational exposure to trichloramine and trihalomethanes adverse health effects in rehabilitation swimming pools

2018 ◽  
Author(s):  
Jessica Westerlund ◽  
Ing-Liss Bryngelsson ◽  
Håkan Westberg ◽  
Håkan Löfstedt ◽  
Pål Graff
Keyword(s):  
Occupational Exposure ◽  
Health Effects ◽  
Swimming Pools ◽  
Adverse Health Effects ◽  
Adverse Health

Health Effects Of Non-Occupational Exposure To Oil Extraction Industry: A Prevalent But Poorly Studied Risk

2015 ◽  
Vol 2015 (1) ◽  
pp. 2005
Author(s):  
Cristina O'Callaghan Gordo ◽  
Martí Orta Martínez ◽  
Manolis Kogevinas
Keyword(s):  
Occupational Exposure ◽  
Health Effects ◽  
Oil Extraction
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