Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H1 Receptor Inverse Agonist

Magnetic Resonance ◽

Late Stage ◽

Resonance Spectroscopy ◽

H1 Receptor ◽

Structure Activity ◽

Human Histamine ◽

Receptor Inverse Agonist

A Workup Protocol Combined with Direct Application of Quantitative Nuclear Magnetic Resonance Spectroscopy of Aqueous Samples from Large-Scale Steam Explosion of Biomass

ACS Omega ◽

10.1021/acsomega.0c05642 ◽

2021 ◽

Author(s):

Camilla Løhre ◽

Jarl Underhaug ◽

Rune Brusletto ◽

Tanja Barth

Keyword(s):

Magnetic Resonance ◽

Quantitative Nuclear Magnetic Resonance

Steam Explosion ◽

Large Scale ◽

Direct Application ◽

Resonance Spectroscopy ◽

Aqueous Samples ◽

Same analytical method for both (bio)assay and zone isolation to identify/quantify bioactive compounds by quantitative nuclear magnetic resonance spectroscopy

Journal of Chromatography A ◽

10.1016/j.chroma.2020.461434 ◽

2020 ◽

Vol 1628 ◽

pp. 461434

Author(s):

Ebrahim Azadniya ◽

Luca Goldoni ◽

Tiziano Bandiera ◽

Gertrud E. Morlock

Keyword(s):

Magnetic Resonance ◽

Bioactive Compounds ◽

Analytical Method ◽

Resonance Spectroscopy ◽

Bio Assay ◽

Determination of Epigoitrin in Radix Isatidis by Solid Phase Extraction-Quantitative Nuclear Magnetic Resonance Spectroscopy

Chinese Journal of Analytical Chemistry ◽

10.1016/s1872-2040(17)61025-9 ◽

2017 ◽

Vol 45 (7) ◽

pp. 1059-1065 ◽

Cited By ~ 2

Author(s):

Xiao-Ting LIU ◽

Shan YU ◽

Ming YUAN ◽

Qiang-Sheng GUO ◽

Can GONG ◽

...

Keyword(s):

Magnetic Resonance ◽

Quantitative Nuclear Magnetic Resonance

Solid Phase Extraction ◽

Solid Phase ◽

Resonance Spectroscopy ◽

Phase Extraction ◽

Radix Isatidis ◽

Determination and Validation of Piracetam in Pharmaceuticals Using Quantitative Nuclear Magnetic Resonance Spectroscopy

Analytical Chemistry Letters ◽

10.1080/22297928.2017.1320227 ◽

2017 ◽

Vol 7 (2) ◽

pp. 271-279

Author(s):

Sobhy M. El-Adl ◽

Mohamed E. El-sadek ◽

Marwa H. Hasan

Keyword(s):

Magnetic Resonance ◽

Resonance Spectroscopy ◽

Assessment of the Purity of Emodin by Quantitative Nuclear Magnetic Resonance Spectroscopy and Mass Balance

Natural Product Sciences ◽

10.20307/nps.2019.25.3.222 ◽

2019 ◽

Vol 25 (3) ◽

pp. 222

Author(s):

Sojung Park ◽

Yu-Jin Choi ◽

Giang Hoang Do ◽

Eun Kyoung Seo ◽

Seunghun Hyun ◽

...

Keyword(s):

Magnetic Resonance ◽

Mass Balance ◽

Resonance Spectroscopy ◽

Biosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic Stability

Drug Metabolism and Disposition ◽

10.1124/dmd.116.069310 ◽

2016 ◽

Vol 44 (5) ◽

pp. 634-646 ◽

Cited By ~ 8

Author(s):

R. S. Obach ◽

G. S. Walker ◽

M. A. Brodney

Keyword(s):

Cytochrome P450 ◽

Magnetic Resonance ◽

Quantitative Nuclear Magnetic Resonance

Metabolic Stability ◽

Resonance Spectroscopy ◽

Cytochrome P450 Enzymes ◽

Human Cytochrome ◽

Application of Quantitative Nuclear Magnetic Resonance Spectroscopy for the Determination of Amantadine and Acyclovir in Plasma and Pharmaceutical Samples

Journal of AOAC International ◽

10.5740/jaoacint.11-165 ◽

2012 ◽

Vol 95 (6) ◽

pp. 1644-1651 ◽

Cited By ~ 4

Author(s):

Alaa A. Salem ◽

Ibrahim M. Abdou ◽

Habiba A. Saleh

Keyword(s):

Magnetic Resonance ◽

Resonance Spectroscopy ◽

Pharmaceutical Samples ◽

Hygroscopic Tendencies of Substances Used as Calibrants for Quantitative Nuclear Magnetic Resonance Spectroscopy

Analytical Chemistry ◽

10.1021/acs.analchem.1c04268 ◽

2021 ◽

Author(s):

Christopher L. Suiter ◽

Jason A. Widegren

Keyword(s):

Magnetic Resonance ◽

Resonance Spectroscopy ◽

Analysis of coumarin and other compounds in commercially available cinnamon and cinnamon supplements utilizing quantitative Nuclear Magnetic Resonance Spectroscopy

Planta Medica ◽

10.1055/s-0035-1556196 ◽

2015 ◽

Vol 81 (11) ◽

Author(s):

KB Killday ◽

MA Markus ◽

C Fischer ◽

KL Colson

Keyword(s):

Magnetic Resonance ◽

Resonance Spectroscopy ◽

Lead Diversification at the Nanomole Scale Using Liver Microsomes and Quantitative Nuclear Magnetic Resonance Spectroscopy: Application to Phosphodiesterase 2 Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b00116 ◽

2018 ◽

Vol 61 (8) ◽

pp. 3626-3640 ◽

Cited By ~ 13

Author(s):

R. Scott Obach ◽

Gregory S. Walker ◽

Raman Sharma ◽

Stephen Jenkinson ◽

Tuan P. Tran ◽

...

Keyword(s):

Magnetic Resonance ◽

Liver Microsomes ◽

Resonance Spectroscopy ◽