scholarly journals Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration

2021 ◽  
Vol 64 (5) ◽  
pp. 2725-2738
Author(s):  
Reiko Watanabe ◽  
Tsuyoshi Esaki ◽  
Rikiya Ohashi ◽  
Masataka Kuroda ◽  
Hitoshi Kawashima ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Prediction Model ◽  
In Silico ◽  
In Silico Prediction ◽  
Brain Capillary ◽  
Brain Penetration ◽  
Brain Capillary Endothelial Cells ◽  
P Glycoprotein ◽  
Capillary Endothelial Cells

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

Life Sciences ◽  
1992 ◽  
Vol 51 (18) ◽  
pp. 1427-1437 ◽  
Author(s):  
Akira Tsuji ◽  
Tetsuya Terasaki ◽  
Yasushi Takabatake ◽  
Yoshiyuki Tenda ◽  
Ikumi Tamai ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Efflux Pump ◽  
Bovine Brain ◽  
Drug Efflux ◽  
Brain Capillary ◽  
Brain Capillary Endothelial Cells ◽  
P Glycoprotein ◽  
Capillary Endothelial Cells ◽  
Drug Efflux Pump

scholarly journals Drug-Induced Trafficking of P-Glycoprotein in Human Brain Capillary Endothelial Cells as Demonstrated by Exposure to Mitomycin C

PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e88154 ◽  
Author(s):  
Andreas Noack ◽  
Sandra Noack ◽  
Andrea Hoffmann ◽  
Katia Maalouf ◽  
Manuela Buettner ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Human Brain ◽  
Mitomycin C ◽  
Drug Induced ◽  
Brain Capillary ◽  
Brain Capillary Endothelial Cells ◽  
P Glycoprotein ◽  
Capillary Endothelial Cells

P-glycoprotein-mediated transport of morphine in brain capillary endothelial cells

1999 ◽  
Vol 58 (6) ◽  
pp. 951-957 ◽  
Author(s):  
Stephen P. Letrent ◽  
Joseph W. Polli ◽  
Joan E. Humphreys ◽  
Gary M. Pollack ◽  
Kenneth R. Brouwer ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Brain Capillary ◽  
Brain Capillary Endothelial Cells ◽  
P Glycoprotein ◽  
Capillary Endothelial Cells
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