Structure–Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.5b00750 ◽

2015 ◽

Vol 58 (15) ◽

pp. 6131-6150 ◽

Author(s):

Niels Krogsgaard-Larsen ◽

Morten Storgaard ◽

Charlotte Møller ◽

Charles S. Demmer ◽

Jeanette Hansen ◽

...

Keyword(s):

Carboxylic Acid ◽

Receptor Antagonist ◽

Glutamate Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Ionotropic Glutamate Receptor ◽

Glutamate Receptor Antagonist ◽

Structure Activity ◽

Relationship Study

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Essential structure of orexin 1 receptor antagonist YNT-707, part V: Structure-activity relationship study of the substituents on the 17-amino group

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2019.126893 ◽

2020 ◽

Vol 30 (3) ◽

pp. 126893

Author(s):

Tsuyoshi Saitoh ◽

Kazunori Seki ◽

Ryo Nakajima ◽

Naoshi Yamamoto ◽

Noriki Kutsumura ◽

...

Keyword(s):

Receptor Antagonist ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Amino Group ◽

Structure Activity ◽

Relationship Study

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A Structure–Activity Relationship Study of Imidazole-5-Carboxylic Acid Derivatives as Angiotensin II Receptor Antagonists Combining 2D and 3D QSAR Methods

Interdisciplinary Sciences Computational Life Sciences ◽

10.1007/s12539-015-0014-1 ◽

2015 ◽

Vol 8 (1) ◽

pp. 1-10 ◽

Author(s):

Mukesh C. Sharma

Keyword(s):

Angiotensin Ii ◽

Carboxylic Acid ◽

3D Qsar ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Structure Activity ◽

Relationship Study ◽

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Synthesis and Structure-Activity Relationship Study of 2-Substituted- 5-(5-nitro-2-thienyl)-1,3,4-thiadiazoles as Anti-Helicobacter pylori Agents

Letters in Drug Design & Discovery ◽

10.2174/157018009789057599 ◽

2009 ◽

Vol 6 (6) ◽

pp. 468-474 ◽

Author(s):

Alireza Foroumadi ◽

Somayeh Sedaghat ◽

Saeed Emami ◽

Maryam Yazdanian ◽

Mohammad Moshafi ◽

...

Keyword(s):

Helicobacter Pylori ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study

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Structure-activity relationship study on the bioreduction of AZO dyes byClostridium paraputrificum

Environmental Toxicology and Chemistry ◽

10.1002/etc.5620200304 ◽

2001 ◽

Vol 20 (3) ◽

pp. 479-484

Author(s):

David Moir ◽

Sheila Masson ◽

Ih Chu

Keyword(s):

Azo Dyes ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study

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Synthesis and preliminary structure-activity relationship study of 3-methylquinazolinone derivatives as EGFR inhibitors with enhanced antiproliferative activities against tumour cells

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2021.1933466 ◽

2021 ◽

Vol 36 (1) ◽

pp. 1205-1216

Author(s):

Yan Zhang ◽

Qin Wang ◽

Luolan Li ◽

Yi Le ◽

Li Liu ◽

...

Keyword(s):

Structure Activity Relationship ◽

Tumour Cells ◽

Egfr Inhibitors ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Antiproliferative Activities

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Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113291 ◽

2021 ◽

pp. 113291

Author(s):

Peng Li ◽

Ying Liu ◽

Hua Yang ◽

Hong-Min Liu

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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Structure–Activity Relationship Study and Biological Evaluation of 2-(Disubstituted phenyl)-indole-5-propanoic Acid Derivatives as GPR40 Full Agonists

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.1c00031 ◽

2021 ◽

Vol 64 (7) ◽

pp. 4130-4149

Author(s):

Xiaodi Zhao ◽

Dong-Oh Yoon ◽

Jaeho Yoo ◽

Hyun-Ju Park

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Propanoic Acid ◽

Structure Activity ◽

Relationship Study

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Strategic structure-activity relationship study on a follistatin-derived myostatin inhibitory peptide

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2021.128163 ◽

2021 ◽

pp. 128163

Author(s):

Mariko Saitoh ◽

Kentaro Takayama ◽

Yoshimi Roppongi ◽

Takahiro Shimada ◽

Akihiro Taguchi ◽

...

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Inhibitory Peptide ◽

Structure Activity ◽

Relationship Study

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Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.03.081 ◽

2017 ◽

Vol 134 ◽

pp. 86-96 ◽

Author(s):

Anna Y. Belorusova ◽

Andrea Martínez ◽

Zoila Gándara ◽

Generosa Gómez ◽

Yagamare Fall ◽

...

Keyword(s):

Vitamin D ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Vitamin D Analogs ◽

Structure Activity ◽

Relationship Study

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Structure–activity relationship study at the 3′-N-position of paclitaxel: synthesis and biological evaluation of 3′-N-acyl-paclitaxel analogues

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(02)00218-3 ◽

2002 ◽

Vol 10 (10) ◽

pp. 3145-3151 ◽

Author(s):

E Roh

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Synthesis And Biological Evaluation

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