scholarly journals Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X)n and (X)nK/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics

2016 ◽  
Vol 16 (2) ◽  
pp. 852-861 ◽  
Author(s):  
Liana Tsiatsiani ◽  
Piero Giansanti ◽  
Richard A. Scheltema ◽  
Henk van den Toorn ◽  
Christopher M. Overall ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Electron Transfer Dissociation ◽  
Peptide Sequencing

Exploration of doubtful cases of leucine and isoleucine discrimination in mass spectrometric peptide sequencing by electron-transfer and higher-energy collision dissociation-based method

2017 ◽  
Vol 23 (6) ◽  
pp. 376-384 ◽  
Author(s):  
Sergey V Kovalyov ◽  
Sergey S Zhokhov ◽  
Ludmila V Onoprienko ◽  
Boris V Vaskovsky ◽  
Albert T Lebedev
Keyword(s):  
Electron Transfer ◽  
Electron Transfer Dissociation ◽  
Protonated Peptide ◽  
Peptide Sequencing ◽  
Mass Spectrometric ◽  
Energy Collision ◽  
Tryptic Peptides ◽  
Radical Site ◽  
Peptide Molecule ◽  
Sequencing Process

Electron-transfer dissociation (ETD) and electron-transfer and higher-energy collision dissociation (EThcD) spectra of short tryptic peptides with leucine/isoleucine residues in neighboring positions demonstrate intensive w-ions. On the contrary, u-ions possess very low intensities (if present at all). Therefore radical site migration is negligible in the applied conditions while ETD (EThcD) spectra allow for the reliable discrimination of the isomeric residues in the sequencing process. The presence of a fragment ion 43.055 mass units lower than z2-ion of peptides with IK sequence at their C-termini was shown to be a result of alternative fragmentation starting from the loss of propylammonium ion from the doubly protonated peptide molecule and formation of an oxazole fragment ion.

scholarly journals Application of electron transfer dissociation mass spectrometry in analyses of non-enzymatically glycated peptides

2007 ◽  
Vol 21 (5) ◽  
pp. 661-666 ◽  
Author(s):  
Qibin Zhang ◽  
Andrej Frolov ◽  
Ning Tang ◽  
Ralf Hoffmann ◽  
Tom van de Goor ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Transfer ◽  
Electron Transfer Dissociation

scholarly journals Trans-Proteomic Pipeline supports and improves analysis of electron transfer dissociation data sets

PROTEOMICS ◽  
2010 ◽  
Vol 10 (6) ◽  
pp. 1190-1195 ◽  
Author(s):  
Eric W. Deutsch ◽  
David Shteynberg ◽  
Henry Lam ◽  
Zhi Sun ◽  
Jimmy K. Eng ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Electron Transfer Dissociation ◽  
Data Sets

scholarly journals Electron transfer dissociation of oligonucleotide cations

2009 ◽  
Vol 283 (1-3) ◽  
pp. 85-93 ◽  
Author(s):  
Suncerae I. Smith ◽  
Jennifer S. Brodbelt
Keyword(s):  
Electron Transfer ◽  
Electron Transfer Dissociation
Sign in / Sign up

Export Citation Format

Share Document