scholarly journals Effect of Deuteration on Phase Behavior of Supported Phospholipid Bilayers: A Spectroelectrochemical Study

Langmuir ◽  
2015 ◽  
Vol 31 (45) ◽  
pp. 12544-12551 ◽  
Author(s):  
Elena Madrid ◽  
Sarah L. Horswell
Keyword(s):  
Phase Behavior ◽  
Phospholipid Bilayers

scholarly journals Effect of Molecular Structure on Electrochemical Phase Behavior of Phospholipid Bilayers on Au(111)

Langmuir ◽  
2021 ◽  
Vol 37 (40) ◽  
pp. 11887-11899
Author(s):  
Philip N. Jemmett ◽  
David C. Milan ◽  
Richard J. Nichols ◽  
Liam R. Cox ◽  
Sarah L. Horswell
Keyword(s):  
Molecular Structure ◽  
Phase Behavior ◽  
Phospholipid Bilayers

scholarly journals Modification of Phospholipid Bilayers Induced by Sulfurated Naphthoquinones

2013 ◽  
Vol 2013 ◽  
pp. 1-8
Author(s):  
Claudio Di Vitta ◽  
Liliana Marzorati ◽  
Sérgio S. Funari
Keyword(s):  
Phase Behavior ◽  
Lipid Bilayer ◽  
Hexagonal Phase ◽  
Phospholipid Bilayers ◽  
Side Chains ◽  
Cubic Phases ◽  
Lamellar Phases ◽  
Alkyl Side Chains

New thionaphthoquinones and their hydroxyl derivatives, bearing alkyl side chains that match the phospholipids POPC and POPE, were synthesized in order to investigate their interactions with lipids. It was observed that, in general, these additives destabilize the lipid bilayer and induce less organized structures with higher curvature, in particular the induction of an hexagonal phase on aqueous POPC mixtures. Moreover, cubic phases, not normally observed in the pure lipids when fully hydrated, were detected. Coexistence of lamellar phases was interpreted as a consequence of microsegregation of the components in the mixtures. These results are in line with previous observations on the effect of structurally similar (hydro)quinones in phase behavior of these lipids.

Effects of Calcium and Neomycin on Phase Behavior of Phospholipid Bilayers

1983 ◽  
Vol 72 (12) ◽  
pp. 1465-1467 ◽  
Author(s):  
Madurai G. Ganesan ◽  
Norman D. Weiner ◽  
Jochen Schacht
Keyword(s):  
Phase Behavior ◽  
Phospholipid Bilayers

Phase behavior of cationic and anionic surfactants at low concentrations

1992 ◽  
Vol 50 (1) ◽  
pp. 694-695
Author(s):  
E. Naranjo
Keyword(s):  
Phase Behavior ◽  
Structural Characterization ◽  
Dynamic Systems ◽  
Anionic Surfactants ◽  
Intermolecular Forces ◽  
Stable Form ◽  
Surfactant Mixtures ◽  
Low Concentrations ◽  
Cationic And Anionic Surfactants ◽  
General Method

Equilibrium vesicles, those which are the stable form of aggregation and form spontaneously on mixing surfactant with water, have never been demonstrated in single component bilayers and only rarely in lipid or surfactant mixtures. Designing a simple and general method for producing spontaneous and stable vesicles depends on a better understanding of the thermodynamics of aggregation, the interplay of intermolecular forces in surfactants, and an efficient way of doing structural characterization in dynamic systems.

Solution Properties and Phase Behavior of Ammonium Hexylene Octyl Succinate in Water and Water-Oil System

1970 ◽  
Vol 3 (1) ◽  
Author(s):  
Md. Hamidul Kabir ◽  
Ravshan Makhkamov ◽  
Shaila Kabir
Keyword(s):  
Critical Micelle Concentration ◽  
Phase Behavior ◽  
Liquid Crystalline ◽  
Carbon Number ◽  
Phase Region ◽  
Solution Properties ◽  
Middle Phase ◽  
Two Phase ◽  
Lamellar Liquid Crystal ◽  
Drug Ingredient

The solution properties and phase behavior of ammonium hexylene octyl succinate (HOS) was investigated in water and water-oil system. The critical micelle concentration (CMC) of HOS is lower than that of anionic surfactants having same carbon number in the lipophilic part. The phase diagrams of a water/ HOS system and water/ HOS/ C10EO8/ dodecane system were also constructed. Above critical micelle concentration, the surfactant forms a normal micellar solution (Wm) at a low surfactant concentration whereas a lamellar liquid crystalline phase (La) dominates over a wide region through the formation of a two-phase region (La+W) in the binary system. The lamellar phase is arranged in the form of a biocompatible vesicle which is very significant for the drug delivery system. The surfactant tends to be hydrophilic when it is mixed with C10EO8 and a middle-phase microemulsion (D) is appeared in the water-surfactant-dodecane system where both the water and oil soluble drug ingredient can be incorporated in the form of a dispersion. Hence, mixing can tune the hydrophile-lipophile properties of the surfactant. Key words: Ammonium hexylene octyl succinate, mixed surfactant, lamellar liquid crystal, middle-phase microemulsion. Dhaka Univ. J. Pharm. Sci. Vol.3(1-2) 2004 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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