scholarly journals Enhanced Oxygen Solubility in Metastable Water under Tension

Langmuir ◽  
2018 ◽  
Vol 34 (40) ◽  
pp. 12017-12024 ◽  
Author(s):  
Pierre Lidon ◽  
Sierra C. Marker ◽  
Justin J. Wilson ◽  
Rebecca M. Williams ◽  
Warren R. Zipfel ◽  
...  
Keyword(s):  
Oxygen Solubility ◽  
Metastable Water

A note on scenarios of metastable water

2010 ◽  
Vol 75 (5) ◽  
pp. 593-605 ◽  
Author(s):  
Jan Jirsák ◽  
Ivo Nezbeda
Keyword(s):  
Computer Simulations ◽  
Equations Of State ◽  
Stability Limit ◽  
Spinodal Curve ◽  
Spinodal Line ◽  
Metastable Water

A recently developed molecular-based equations of state for water are analyzed with respect to the behavior of the liquid spinodal curve. It is shown that all of them yield the spinodal exhibiting a minimum in accordance with Speedy’s stability-limit conjecture and with the behavior predicted by the accurate (but purely empirical) IAPWS-95 equation. It means that the considered equations of state give consistent results but qualitatively different from those resulting from available computer simulations, which yield a monotonic spinodal line.

scholarly journals Biomimetic oxygen delivery nanoparticles for enhancing photodynamic therapy in triple-negative breast cancer

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Hanyi Fang ◽  
Yongkang Gai ◽  
Sheng Wang ◽  
Qingyao Liu ◽  
Xiao Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Cancer Cell ◽  
Triple Negative Breast Cancer ◽  
Oxygen Delivery ◽  
Therapeutic Efficacy ◽  
Triple Negative ◽  
Oxygen Solubility ◽  
Post Injection

Abstract Background Triple-negative breast cancer (TNBC) is a kind of aggressive breast cancer with a high rate of metastasis, poor overall survival time, and a low response to targeted therapies. To improve the therapeutic efficacy and overcome the drug resistance of TNBC treatments, here we developed the cancer cell membrane-coated oxygen delivery nanoprobe, CCm–HSA–ICG–PFTBA, which can improve the hypoxia at tumor sites and enhance the therapeutic efficacy of the photodynamic therapy (PDT), resulting in relieving the tumor growth in TNBC xenografts. Results The size of the CCm–HSA–ICG–PFTBA was 131.3 ± 1.08 nm. The in vitro 1O2 and ROS concentrations of the CCm–HSA–ICG–PFTBA group were both significantly higher than those of the other groups (P < 0.001). In vivo fluorescence imaging revealed that the best time window was at 24 h post-injection of the CCm–HSA–ICG–PFTBA. Both in vivo 18F-FMISO PET imaging and ex vivo immunofluorescence staining results exhibited that the tumor hypoxia was significantly improved at 24 h post-injection of the CCm–HSA–ICG–PFTBA. For in vivo PDT treatment, the tumor volume and weight of the CCm–HSA–ICG–PFTBA with NIR group were both the smallest among all the groups and significantly decreased compared to the untreated group (P < 0.01). No obvious biotoxicity was observed by the injection of CCm–HSA–ICG–PFTBA till 14 days. Conclusions By using the high oxygen solubility of perfluorocarbon (PFC) and the homologous targeting ability of cancer cell membranes, CCm–HSA–ICG–PFTBA can target tumor tissues, mitigate the hypoxia of the tumor microenvironment, and enhance the PDT efficacy in TNBC xenografts. Furthermore, the HSA, ICG, and PFC are all FDA-approved materials, which render the nanoparticles highly biocompatible and enhance the potential for clinical translation in the treatment of TNBC patients.

Perfluorinated organics regulating Li2O2 formation and improving stability for Li–oxygen batteries

2021 ◽  
Vol 57 (24) ◽  
pp. 3030-3033
Author(s):  
Yuling Wang ◽  
Fan Bai ◽  
Aiping Wang ◽  
Zhonghui Cui ◽  
Da Wang ◽  
...  
Keyword(s):  
High Capacity ◽  
Oxygen Solubility ◽  
Artificial Blood ◽  
Lithium Oxygen Batteries

Perfluorotributylamine, an artificial blood, is introduced into lithium–oxygen batteries due to its excellent oxygen solubility, achieving superior high capacity and long stability.

scholarly journals Assessment of Water Quality Profile Using Numerical Modeling Approach in Major Climate Classes of Asia

2018 ◽  
Vol 15 (10) ◽  
pp. 2258 ◽  
Author(s):  
Muhammad Mazhar Iqbal ◽  
Muhammad Shoaib ◽  
Hafiz Umar Farid ◽  
Jung Lyul Lee
Keyword(s):  
Water Quality ◽  
Water Environment ◽  
Oxygen Demand ◽  
Surface Water Quality ◽  
Water Quality Model ◽  
Oxygen Solubility ◽  
Quality Model ◽  
Spatial Profile ◽  
Climatic Regions ◽  
Model Predictions

A river water quality spatial profile has a diverse pattern of variation over different climatic regions. To comprehend this phenomenon, our study evaluated the spatial scale variation of the Water Quality Index (WQI). The study was carried out over four main climatic classes in Asia based on the Koppen-Geiger climate classification system: tropical, temperate, cold, and arid. The one-dimensional surface water quality model, QUAL2Kw was selected and compared for water quality simulations. Calibration and validation were separately performed for the model predictions over different climate classes. The accuracy of the water quality model was assessed using different statistical analyses. The spatial profile of WQI was calculated using model predictions based on dissolved oxygen (DO), biological oxygen demand (BOD), nitrate (NO3), and pH. The results showed that there is a smaller longitudinal variation of WQI in the cold climatic regions than other regions, which does not change the status of WQI. Streams from arid, temperate, and tropical climatic regions show a decreasing trend of DO with respect to the longitudinal profiles of main river flows. Since this study found that each climate zone has the different impact on DO dynamics such as reaeration rate, reoxygenation, and oxygen solubility. The outcomes obtained in this study are expected to provide the impetus for developing a strategy for the viable improvement of the water environment.

scholarly journals OXYGEN SOLUBILITY IN TITANIUM-CONTAINING Fe – Ni MELTS

2015 ◽  
Vol 57 (11) ◽  
pp. 54
Author(s):  
A. A. Aleksandrov ◽  
V. Ya. Dashevskii
Keyword(s):  
Oxygen Solubility

scholarly journals PENGARUH JUMLAH TITIK AERASI PADA BUDIDAYA UDANG VANAME, Litopenaeus vannamei

2018 ◽  
Vol 10 (3) ◽  
pp. 727-738
Author(s):  
. Makmur ◽  
Hidayat Suryanto Suwoyo ◽  
Mat Fahrur ◽  
Rachman Syah
Keyword(s):  
Dissolved Oxygen ◽  
Total Nitrogen ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Shrimp Farming ◽  
Oxygen Solubility ◽  
Dissolved Oxygen Concentration ◽  
Feed Conversion ◽  
Aeration System ◽  
Shrimp Production

ABSTRAKSalah satu upaya untuk meningkatkan oksigen terlarut di perairan tambak dapat dilakukan melalui sistem aerasi dasar. Jumlah titik aerasi dasar diduga mempengaruhi kelarutan oksigen dan berdampak pada performa  budidaya udang di tambak. Penelitian ini menggunakan dua petak tambak beton masing-masing 1.000 m2 dilengkapi dengan sistem aerasi dasar yang terbuat dari  rubber diffuser sepanjang 100 cm, berjumlah 140 buah (Perlakuan A) dan 70 buah (Perlakuan B). Benur udang vaname PL-9 ditebar dengan padat penebaran 600 ekor/m2 dan dipelihara selama 70 hari. Perlakuan A menghasilkan kelarutan oksigen 3,04-10,36 (6,60±1,07) mg/L lebih tinggi dibandingkan perlakuan B dengan kisaran oksigen terlarut 2,77-7,92 (6,08±0,95) mg/L. Sebaliknya parameter nitrit, total nitrogen, phosphat dan bahan organik terlarut lebih rendah di perlakuan A. Produksi, sintasan, dan rasio konversi pakan pada perlakuan A masing-masing 5.620 kg, 93,6% dan 1,12 dan perlakuan B masing-masing 4.000 kg, 80,7% dan 1,51. Perlakuan A menghasilkan performa budidaya lebih baik dibandingkan perlakuan B. Untuk meningkatkan pasokan oksigen terlarut di tambak dapat digunakan rubber diffuser yang dihubungkan dengan blower. ABSTRACTOne effort to increase dissolved oxygen concentration in pond waters is by applying bottom aeration system. The number of aeration point in the pond bottom allegedly affects oxygen solubility and shrimp farming performance. This study utilized two concreted ponds of 1000 m2 each equipped with two bottom aeration systems built by 100 cm long of rubber diffuser, totaling 140 pieces (Treatment A) and 70 pieces (Treatment B). The PL-9 of L. vannamei were stocked with density of 600 ind/m2 and reared for 70 days. Treatment A resulted dissolved oxygen of 3.04-10.36 (6.60±1.07) mg/L which were higher than Treatment B where the range of dissolved oxygen were 2.77-7.92 (6.08±0.95) mg/L. In contrast, nitrite, total nitrogen, phosphate and dissolved organic matter were lower within treatment A. Shrimp production, survival rate and feed conversion ratio in Treatment A were5, 620 kg, 93.6% and 1.12, respectively; whereas in treatment B were 4,000 kg, 80.7% and 1.51. Treatment A resulted in a better the L. vannamei farming compared to treatment B.  To increase the supply of dissolved oxygen in the pond, a rubber diffuser can be used which is connected to a blower.

scholarly journals Pengaruh Lama Waktu Osmosis Terhadap Kandungan Vitamin C dalam Minuman Sari buah Stroberi dan Apel

2019 ◽  
Vol 4 (1) ◽  
pp. 19-22
Author(s):  
Vika Ayu Devianti ◽  
Anisa Rizki Amalia
Keyword(s):  
Heavy Metal ◽  
Vitamin C ◽  
Human Body ◽  
Apple Juice ◽  
Fruit Juice ◽  
Metal Cations ◽  
Oxygen Solubility ◽  
Heavy Metal Cations ◽  
Sugar Addition ◽  
Strawberry Juice

ABSTRAKVitamin C berperan penting dalam mempertahankan daya tahan tubuh. Vitamin C mudah teroksidasi dan tidakstabil dalam bentuk larutan. Vitamin C banyak ditemukan dalam buah – buahan, diantaranya adalah apel danstroberi. Apel dan stroberi ini sering diolah dalam bentuk minuman sari buah melalui proses ekstraksi osmosis. Tujuan penelitian ini adalah untuk mengetahui pengaruh lama waktu osmosis (30 dan 60 menit) dan penambahan gula 10% terhadap kandungan vitamin C dalam minuman sari buah apel dan stroberi. Penambahan gula 10% mampu memperkecil penurunan kadar vitamin C dalam minuman sari buah. Penurunan kadar vitamin C pada sampel sari buah stroberi tanpa penambahan gula adalah 18,7% pada menit ke-30 dan 37,5% pada menit ke-60, sedangkan penambahan gula 10% mengalami penurunan sebesar 2,7% pada menit ke-30 dan 7,9% pada menit ke-60. Penurunan kadar vitamin C pada sampel sari buah apel tanpa penambahan gula adalah 24,2% pada menitke-30 dan 41,6% pada menit ke-60, sedangkan penambahan gula 10% mengalami penurunan sebesar 10,6% pada menit ke-30 dan 21,4% pada menit ke-60.Kata kunci: Vitamin C, sukrosa, minuman sari buah, apel, strawberry, osmosis ABSTRACTVitamin C plays an important in human body. Vitamin C is easily degraded by heat, light, oxygen, and heavy metal cations. Vitamin C mostly found in fruits, such as strawberry and apple. Generally strawberry and apple are processed into fruit juice by adding sugar using osmosis extraction. The objective of this research is to findout the effect of osmosis time and sugar addition towards the vitamin C level in strawberry and apple juice. The result showed that sugar addition can affect the vitamin C level in strawberry and apple juice. Sugars can decrease the oxygen solubility causing less oxygen availability for oxidation of vitamin C. The diminish of vitamin C content in apple juice with sugar addition were 10,6% and 21,4% for 30 and 60 minutes of osmosis time; while strawberry juice with sugar addition able to lowering vitamin C level until 18,7% and 37,5% for 30 and 60 minutes of osmosis time.Keywords: Vitamin C, sucrose, apple juice, strawberry juice, osmosis,

scholarly journals Biomimetic Oxygen Delivery Nanoparticles for Enhancing Photodynamic Therapy in Triple-negative Breast Cancer

2021 ◽  
Author(s):  
Hanyi Fang ◽  
Yongkang Gai ◽  
Sheng Wang ◽  
Qingyao Liu ◽  
Xiao Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Cancer Cell ◽  
Triple Negative Breast Cancer ◽  
Oxygen Delivery ◽  
Therapeutic Efficacy ◽  
Triple Negative ◽  
Oxygen Solubility ◽  
Post Injection

Abstract Background Triple-negative breast cancer (TNBC) is a kind of aggressive breast cancer with a high rate of metastasis, poor overall survival time, and a low response to targeted therapies. To improve the therapeutic efficacy and overcome the drug resistance of TNBC treatments, here we developed the cancer cell membrane-coated oxygen delivery nanoprobe, CCm-HSA-ICG-PFTBA, which can improve the hypoxia at tumor sites and enhance the therapeutic efficacy of the photodynamic therapy (PDT), resulting in relieving the tumor growth in TNBC xenografts. Results The size of the CCm-HSA-ICG-PFTBA was 131.3 ± 1.08 nm. The in vitro 1O2 and ROS concentrations of the CCm-HSA-ICG-PFTBA group were both significantly higher than those of the other groups (P < 0.001). In vivo fluorescence imaging revealed that the best time window was at 24 h post-injection of the CCm-HSA-ICG-PFTBA. Both in vivo 18F-FMISO PET imaging and ex vivo immunofluorescence staining results exhibited that the tumor hypoxia was significantly improved at 24 h post-injection of the CCm-HSA-ICG-PFTBA. For in vivo PDT treatment, the tumor volume and weight of the CCm-HSA-ICG-PFTBA with NIR group were both the smallest among all the groups and significantly decreased compared to the untreated group (P < 0.01). No obvious biotoxicity was observed by the injection of CCm-HSA-ICG-PFTBA till 14 days. Conclusions By using the high oxygen solubility of perfluorocarbon (PFC) and the homologous targeting ability of cancer cell membranes, CCm-HSA-ICG-PFTBA can target tumor tissues, mitigate the hypoxia of the tumor microenvironment, and enhance the PDT efficacy in TNBC xenografts. Furthermore, the HSA, ICG, and PFC are all FDA-approved materials, which render the nanoparticles highly biocompatible and enhance the potential for clinical translation in the treatment of TNBC patients.

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