Preclinical Dose-Escalation Study of ZSJ-0228, a Polymeric Dexamethasone Prodrug, in the Treatment of Murine Lupus Nephritis

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.1c00567 ◽

2021 ◽

Author(s):

Zhifeng Zhao ◽

Xiaoke Xu ◽

Haochen Jiang ◽

Kirk W. Foster ◽

Zhenshan Jia ◽

...

Keyword(s):

Lupus Nephritis ◽

Dose Escalation ◽

Murine Lupus ◽

Dose Escalation Study

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Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study

Arthritis Research & Therapy ◽

10.1186/ar3268 ◽

2011 ◽

Vol 13 (2) ◽

Author(s):

Hanns-Martin Lorenz ◽

Wilhelm H Schmitt ◽

Vladimir Tesar ◽

Ulf Müller-Ladner ◽

Ingo Tarner ◽

...

Keyword(s):

Lupus Nephritis ◽

Dose Escalation ◽

The Novel ◽

Dose Escalation Study ◽

Active Lupus Nephritis ◽

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Use of Two Technologies, Singulex Single Molecule Counting (SMC)TMand Meso Scale Discovery&[reg](MSD) Technology for Drug Levels Determination of an Antibody Therapeutic, MK-A, in Human Serum in a Dose Escalation Study

10.26226/morressier.57d6b2bbd462b8028d88cc5b ◽

2016 ◽

Author(s):

Phyllis Conliffe

Keyword(s):

Human Serum ◽

Single Molecule ◽

Dose Escalation ◽

Meso Scale Discovery ◽

Dose Escalation Study ◽

Drug Levels ◽

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Phase 1, First in Human, Open-Label, Dose-Escalation Study of 609A in China

Case Medical Research ◽

10.31525/ct1-nct03998345 ◽

2019 ◽

Author(s):

Keyword(s):

Dose Escalation ◽

Phase 1 ◽

Dose Escalation Study ◽

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Dose-escalation Study of Oral Administration of LP-108 in Patients With Relapsed or Refractory Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML)

Case Medical Research ◽

10.31525/ct1-nct04139434 ◽

2019 ◽

Author(s):

Keyword(s):

Acute Myeloid Leukemia ◽

Oral Administration ◽

Dose Escalation ◽

Myelodysplastic Syndromes ◽

Myeloid Leukemia ◽

Chronic Myelomonocytic Leukemia ◽

Dose Escalation Study ◽

Myelomonocytic Leukemia ◽

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Faculty Opinions recommendation of A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13409136.14780164 ◽

2011 ◽

Author(s):

John Laffey ◽

Mairead Hayes

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Mesenchymal Stem Cells ◽

Dose Escalation ◽

Human Mesenchymal Stem Cells ◽

Dose Escalation Study ◽

Double Blind ◽

Double Blind Placebo ◽

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Faculty Opinions recommendation of The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.6706956.8652054 ◽

2011 ◽

Author(s):

Tak Mao Chan ◽

Susan Yung

Keyword(s):

Lupus Nephritis ◽

B Cell ◽

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Faculty Opinions recommendation of The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.6706956.7829056 ◽

2011 ◽

Author(s):

Chandra Mohan ◽

Jack Hutcheson

Keyword(s):

Lupus Nephritis ◽

B Cell ◽

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Faculty Opinions recommendation of The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.6706956.7599057 ◽

2010 ◽

Author(s):

Sarah Gaffen ◽

Jill Kramer

Keyword(s):

Lupus Nephritis ◽

B Cell ◽

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Faculty Opinions recommendation of Holmium-166 radioembolisation in patients with unresectable, chemorefractory liver metastases (HEPAR trial): a phase 1, dose-escalation study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717955175.793461372 ◽

2012 ◽

Author(s):

Philip Rosenthal

Keyword(s):

Liver Metastases ◽

Dose Escalation ◽

Phase 1 ◽

Dose Escalation Study

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Faculty Opinions recommendation of MicroRNA-130b Ameliorates Murine Lupus Nephritis Through Targeting the Type I Interferon Pathway on Renal Mesangial Cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726310584.793533030 ◽

2017 ◽

Author(s):

Tak Mao Chan ◽

Susan Yung

Keyword(s):

Lupus Nephritis ◽

Mesangial Cells ◽

Type I Interferon ◽

Type I ◽

Murine Lupus ◽

Interferon Pathway

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