scholarly journals Extending the Near-Infrared Emission Range of Indium Phosphide Quantum Dots for Multiplexed In Vivo Imaging

Nano Letters ◽  
2021 ◽  
Author(s):  
Alexander M. Saeboe ◽  
Alexey Yu. Nikiforov ◽  
Reyhaneh Toufanian ◽  
Joshua C. Kays ◽  
Margaret Chern ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Indium Phosphide ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Infrared Emission ◽  
Near Infrared Emission

scholarly journals Extending the Near Infrared Emission Range of Indium Phosphide Quantum Dots for Multiplexed In Vivo Imaging

2021 ◽  
Author(s):  
Alexander M. Saeboe ◽  
Alexey Y. Nikiforov ◽  
Reyhaneh Toufanian ◽  
Joshua C. Kays ◽  
Margaret Chern ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Indium Phosphide ◽  
Near Infrared ◽  
Infrared Emission ◽  
Full Potential ◽  
Lymph Node Imaging ◽  
Nir Imaging ◽  
Near Infrared Emission ◽  
Tunable Emission

AbstractThis report of the reddest emitting indium phosphide quantum dots (InP QDs) to date demonstrates tunable, near infrared (NIR) photoluminescence and fluorescence multiplexing in the first optical tissue window with a material that avoids toxic constituents. This synthesis overcomes the InP synthesis “growth bottleneck” and extends the emission peak of InP QDs deeper into the first optical tissue window using an inverted QD heterostructure. The ZnSe/InP/ZnS core/shell/shell structure is designed to produce emission from excitons with heavy holes confined in InP shells wrapped around larger-bandgap ZnSe cores and protected by a second shell of ZnS. The InP QDs exhibit InP shell thickness-dependent tunable emission with peaks ranging from 515 – 845 nm. The high absorptivity of InP leads to effective absorbance and photoexcitation of the QDs with UV, visible, and NIR wavelengths in particles with diameters of eight nanometers or less. These nanoparticles extend the range of tunable direct-bandgap emission from InP-based nanostructures, effectively overcoming a synthetic barrier that has prevented InP-based QDs from reaching their full potential as NIR imaging agents. Multiplexed lymph node imaging in a mouse model shows the potential of the NIR-emitting InP particles for in vivo imaging.

Molecular Chemiluminescent Probes with a Very Long Near‐Infrared Emission Wavelength for in Vivo Imaging

2020 ◽  
Author(s):  
Jingsheng Huang ◽  
Yuyan Jiang ◽  
Jingchao Li ◽  
Jiaguo Huang ◽  
Kanyi Pu
Keyword(s):  
In Vivo Imaging ◽  
Near Infrared ◽  
Infrared Emission ◽  
Emission Wavelength ◽  
Near Infrared Emission

AIEgen Nanoparticles of Arylamino Fumaronitrile Derivative with High Near-Infrared Emission for Two-Photon Imaging and in Vivo Cell Tracking

2018 ◽  
Vol 2 (1) ◽  
pp. 430-436 ◽  
Author(s):  
Zhonghua Liu ◽  
Fang Liu ◽  
Yijian Gao ◽  
Weixia Qing ◽  
Yongwei Huang ◽  
...  
Keyword(s):  
Cell Tracking ◽  
Near Infrared ◽  
Infrared Emission ◽  
Two Photon ◽  
Photon Imaging ◽  
Two Photon Imaging ◽  
Near Infrared Emission

Near-infrared in vivo bioimaging using a molecular upconversion probe

2016 ◽  
Vol 52 (47) ◽  
pp. 7466-7469 ◽  
Author(s):  
Yi Liu ◽  
Qianqian Su ◽  
Xianmei Zou ◽  
Min Chen ◽  
Wei Feng ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Emission ◽  
Near Infrared Emission

A molecular upconversion probe with intense near-infrared emission has tremendous potential in bioimaging.

Fluorescence resonance energy transfer (FRET) based nanoparticles composed of AIE luminogens and NIR dyes with enhanced three-photon near-infrared emission for in vivo brain angiography

Nanoscale ◽  
2018 ◽  
Vol 10 (21) ◽  
pp. 10025-10032 ◽  
Author(s):  
Wen Liu ◽  
Yalun Wang ◽  
Xiao Han ◽  
Ping Lu ◽  
Liang Zhu ◽  
...  
Keyword(s):  
Near Infrared ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Infrared Emission ◽  
Biological Imaging ◽  
High Contrast ◽  
Nir Dyes ◽  
Nir Fluorescence ◽  
Near Infrared Emission

Near-infrared (NIR) fluorescence is very important for high-contrast biological imaging of high-scattering tissues such as brain tissue.

Tailored Photoluminescence Properties of Ag(In,Ga)Se2 Quantum Dots for Near-Infrared In Vivo Imaging

2020 ◽  
Vol 3 (4) ◽  
pp. 3275-3287 ◽  
Author(s):  
Tatsuya Kameyama ◽  
Hiroki Yamauchi ◽  
Takahisa Yamamoto ◽  
Toshiki Mizumaki ◽  
Hiroshi Yukawa ◽  
...  
Keyword(s):  
Quantum Dots ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Photoluminescence Properties

scholarly journals Biocompatible and Biodegradable Magnesium Oxide Nanoparticles with In Vitro Photostable Near-Infrared Emission: Short-Term Fluorescent Markers

Nanomaterials ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 1360 ◽  
Author(s):  
Asma Khalid ◽  
Romina Norello ◽  
Amanda N. Abraham ◽  
Jean-Philippe Tetienne ◽  
Timothy J. Karle ◽  
...  
Keyword(s):  
Magnesium Oxide ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Cultured Cells ◽  
Infrared Emission ◽  
Fluorescent Nanoparticles ◽  
Short Term ◽  
Fluorescent Markers

Imaging of biological matter by using fluorescent nanoparticles (NPs) is becoming a widespread method for in vitro imaging. However, currently there is no fluorescent NP that satisfies all necessary criteria for short-term in vivo imaging: biocompatibility, biodegradability, photostability, suitable wavelengths of absorbance and fluorescence that differ from tissue auto-fluorescence, and near infrared (NIR) emission. In this paper, we report on the photoluminescent properties of magnesium oxide (MgO) NPs that meet all these criteria. The optical defects, attributed to vanadium and chromium ion substitutional defects, emitting in the NIR, are observed at room temperature in NPs of commercial and in-house ball-milled MgO nanoparticles, respectively. As such, the NPs have been successfully integrated into cultured cells and photostable bright in vitro emission from NPs was recorded and analyzed. We expect that numerous biotechnological and medical applications will emerge as this nanomaterial satisfies all criteria for short-term in vivo imaging.

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