iRGD-Decorated Polymeric Nanoparticles for the Efficient Delivery of Vandetanib to Hepatocellular Carcinoma: Preparation and in Vitro and in Vivo Evaluation

2016 ◽  
Vol 8 (30) ◽  
pp. 19228-19237 ◽  
Author(s):  
Jianguo Wang ◽  
Hangxiang Wang ◽  
Jie Li ◽  
Zhikun Liu ◽  
Haiyang Xie ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Polymeric Nanoparticles ◽  
In Vivo Evaluation ◽  
Efficient Delivery

In vitro and in vivo evaluation of folate-mediated PEGylated nanostructured lipid carriers for the efficient delivery of furanodiene

2017 ◽  
Vol 43 (10) ◽  
pp. 1610-1618 ◽  
Author(s):  
Jianmei Zhang ◽  
Yunpeng He ◽  
Jianqi Jiang ◽  
Meng Li ◽  
Chenhao Jin ◽  
...  
Keyword(s):  
Nanostructured Lipid Carriers ◽  
In Vivo Evaluation ◽  
Efficient Delivery

scholarly journals In vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy

Drug Delivery ◽  
2017 ◽  
Vol 24 (1) ◽  
pp. 459-466 ◽  
Author(s):  
Can Huang ◽  
Na-Mei Li ◽  
Pei Gao ◽  
Sa Yang ◽  
Qian Ning ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
In Vivo Evaluation ◽  
Macromolecular Prodrug

Preparation and in vitro-in vivo evaluation of salmon calcitonin-loaded polymeric nanoparticles

2009 ◽  
pp. 1-12 ◽  
Author(s):  
Eliza Glowka ◽  
Anne Sapin-Minet ◽  
Pierre Leroy ◽  
Janina Lulek ◽  
Philippe Maincent
Keyword(s):  
Salmon Calcitonin ◽  
Polymeric Nanoparticles ◽  
In Vivo Evaluation

The Promise of miRNA Replacement Therapy for Hepatocellular Carcinoma

2019 ◽  
Vol 19 (5) ◽  
pp. 290-304 ◽  
Author(s):  
Mahmoud Elhefnawi ◽  
Zeinab Salah ◽  
Bangly Soliman
Keyword(s):  
Hepatocellular Carcinoma ◽  
Clinical Trials ◽  
Mortality Rate ◽  
Tumor Suppressor ◽  
Noncoding Rnas ◽  
Efficient Delivery ◽  
Post Transcriptional Regulation ◽  
Tumor Suppressor Mirnas

Hepatocellular carcinoma is a devastating tumor which accounts for death mortality rate 94% globally, and about 780,000 new cases each year. Tumor suppressor miRNAs represent a class of noncoding RNAs, which exhibit decreased or inhibited expression in the case of carcinogenesis. Therefore, the replacement of these molecules leads to post-transcriptional regulation of tens to hundreds of oncogenic targets and limiting the tumor. Interestingly, there is a group of tumor silencer miRNAs that have been highlighted in HCC and herein, our review will discuss the prominent examples of these miRs in terms of their efficient delivery using vectors, nano-delivery systems, their successful models either in vitro or in vivo and pre-clinical trials. Collectively, tumor suppressor miRNAs can act as novel therapeutics for HCC and more studies should be directed towards these promising therapeutics.

scholarly journals In Vitro and In Vivo Evaluation of Oral Heparin–Loaded Polymeric Nanoparticles in Rabbits

Circulation ◽  
2002 ◽  
Vol 105 (2) ◽  
pp. 230-235 ◽  
Author(s):  
Yuyan Jiao ◽  
Nathalie Ubrich ◽  
Monique Marchand-Arvier ◽  
Claude Vigneron ◽  
Maurice Hoffman ◽  
...  
Keyword(s):  
Polymeric Nanoparticles ◽  
In Vivo Evaluation

Paclitaxel-loaded polymeric nanoparticles combined with chronomodulated chemotherapy on lung cancer: In vitro and in vivo evaluation

2017 ◽  
Vol 516 (1-2) ◽  
pp. 313-322 ◽  
Author(s):  
Jie Hu ◽  
Shaozhi Fu ◽  
Qiuxia Peng ◽  
YunWei Han ◽  
Jie Xie ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Polymeric Nanoparticles ◽  
In Vivo Evaluation
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