macromolecular prodrug
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scholarly journals Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Wei Zhang ◽  
Tianjiao Ji ◽  
Yang Li ◽  
Yueqin Zheng ◽  
Manisha Mehta ◽  
...  
Keyword(s):  
Local Anesthesia ◽  
Local Anesthetics ◽  
Triggered Release ◽  
On Demand ◽  
Macromolecular Prodrug

Hyaluronic Acid-Tacrolimus Bioconjugate: Synthesis, Characterization, and Pharmacokinetic Investigation of an Acid-Responsive Macromolecular Prodrug

2019 ◽  
Vol 2 (11) ◽  
pp. 4728-4736 ◽  
Author(s):  
Divya Dheer ◽  
Rahul Gupta ◽  
Davinder Singh ◽  
Asmita Magotra ◽  
Gurdarshan Singh ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Pharmacokinetic Investigation ◽  
Macromolecular Prodrug

Design of Macromolecular Prodrug of Cisplatin Attached to Dextran through Coordinate Bond

2019 ◽  
pp. 239-250
Author(s):  
Tatsuro Ouchi ◽  
Mitsuo Matsumoto ◽  
Tatsunori Masunaga ◽  
Yichi Ohya ◽  
Katsurou Ichinose ◽  
...  
Keyword(s):  
Coordinate Bond ◽  
Macromolecular Prodrug

Delivery of Liver-Specific miRNA-122 Using a Targeted Macromolecular Prodrug toward Synergistic Therapy for Hepatocellular Carcinoma

2019 ◽  
Vol 11 (11) ◽  
pp. 10578-10588 ◽  
Author(s):  
Qian Ning ◽  
Yu-Feng Liu ◽  
Peng-Ju Ye ◽  
Pei Gao ◽  
Zhi-Ping Li ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Macromolecular Prodrug

Fully synthetic macromolecular prodrug chemotherapeutics with EGFR targeting and controlled camptothecin release kinetics

2018 ◽  
Vol 9 (42) ◽  
pp. 5224-5233 ◽  
Author(s):  
Hanna Freeman ◽  
Selvi Srinivasan ◽  
Debobrato Das ◽  
Patrick S. Stayton ◽  
Anthony J. Convertine
Keyword(s):  
Release Kinetics ◽  
Macromolecular Prodrug

The development of fully polymerizable, peptide-targeted, camptothecin polymeric prodrugs are reported.

scholarly journals Cover Feature: A pH-sensitive Macromolecular Prodrug as TLR7/8 Targeting Immune Response Modifier (Chem. Eur. J. 70/2017)

2017 ◽  
Vol 23 (70) ◽  
pp. 17624-17624
Author(s):  
Stefan Aichhorn ◽  
Anne Linhardt ◽  
Angela Halfmann ◽  
Markus Nadlinger ◽  
Stefanie Kirchberger ◽  
...  
Keyword(s):  
Immune Response ◽  
Ph Sensitive ◽  
Response Modifier ◽  
Macromolecular Prodrug ◽  
Immune Response Modifier

scholarly journals A pH-sensitive Macromolecular Prodrug as TLR7/8 Targeting Immune Response Modifier

2017 ◽  
Vol 23 (70) ◽  
pp. 17721-17726 ◽  
Author(s):  
Stefan Aichhorn ◽  
Anne Linhardt ◽  
Angela Halfmann ◽  
Markus Nadlinger ◽  
Stefanie Kirchberger ◽  
...  
Keyword(s):  
Immune Response ◽  
Ph Sensitive ◽  
Response Modifier ◽  
Macromolecular Prodrug ◽  
Immune Response Modifier

scholarly journals In vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy

Drug Delivery ◽  
2017 ◽  
Vol 24 (1) ◽  
pp. 459-466 ◽  
Author(s):  
Can Huang ◽  
Na-Mei Li ◽  
Pei Gao ◽  
Sa Yang ◽  
Qian Ning ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
In Vivo Evaluation ◽  
Macromolecular Prodrug

scholarly journals Surface functionalization of superparamagnetic nanoparticles by an acid-liable polysaccharide-based prodrug for combinatorial monitoring and chemotherapy of hepatocellular carcinoma

RSC Advances ◽  
2017 ◽  
Vol 7 (66) ◽  
pp. 41919-41928 ◽  
Author(s):  
Chaoping Fu ◽  
Rui-Meng Yang ◽  
Li Wang ◽  
Nan-nan Li ◽  
Meng Qi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hyaluronic Acid ◽  
Iron Oxide ◽  
Surface Functionalization ◽  
Superparamagnetic Nanoparticles ◽  
Liver Carcinoma ◽  
Oxide Nanoparticles ◽  
Doxorubicin Hydrochloride ◽  
Macromolecular Prodrug ◽  
Acid Labile

For combinatorial monitoring and chemotherapy of liver carcinoma, the macromolecular prodrug based on hyaluronic acid and doxorubicin hydrochloride was prepared by an acid-labile linkage and conjugated with amine-modified iron oxide nanoparticles.

Polysaccharide-based materials in macromolecular prodrug design and development

2016 ◽  
Vol 62 (2) ◽  
pp. 78-98 ◽  
Author(s):  
M. A. Hussain ◽  
K. Abbas ◽  
I. Jantan ◽  
S. N. A. Bukhari
Keyword(s):  
Design And Development ◽  
Macromolecular Prodrug
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