Three-Dimensional Porous Scaffolds with Biomimetic Microarchitecture and Bioactivity for Cartilage Tissue Engineering

2019 ◽  
Vol 11 (40) ◽  
pp. 36359-36370 ◽  
Author(s):  
Yaqiang Li ◽  
Yanqun Liu ◽  
Xiaowei Xun ◽  
Wei Zhang ◽  
Yong Xu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Cartilage Tissue ◽  
Porous Scaffolds

Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique

Biomaterials ◽  
2004 ◽  
Vol 25 (18) ◽  
pp. 4149-4161 ◽  
Author(s):  
T.B.F. Woodfield ◽  
J. Malda ◽  
J. de Wijn ◽  
F. Péters ◽  
J. Riesle ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Cartilage Tissue ◽  
Porous Scaffolds ◽  
Deposition Technique ◽  
Fiber Deposition

Potential of silk fibroin/chondrocyte constructs of muga silkworm Antheraea assamensis for cartilage tissue engineering

2016 ◽  
Vol 4 (21) ◽  
pp. 3670-3684 ◽  
Author(s):  
Nandana Bhardwaj ◽  
Yogendra Pratap Singh ◽  
Dipali Devi ◽  
Raghuram Kandimalla ◽  
Jibon Kotoky ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Silk Fibroin ◽  
Cartilage Repair ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Cartilage Tissue ◽  
Porous Scaffolds ◽  
Muga Silkworm ◽  
Antheraea Assamensis ◽  
Further Development

A three-dimensional porous scaffolds based on muga silkworm, Antheraea assamensis was fabricated and well characterized for cartilage tissue engineering, which may present as noteworthy targets for the further development in chondrocytes based cartilage repair.

Poly(N -isopropylacrylamide) hydrogel/chitosan scaffold hybrid for three-dimensional stem cell culture and cartilage tissue engineering

2016 ◽  
Vol 104 (11) ◽  
pp. 2764-2774 ◽  
Author(s):  
Amir Mellati ◽  
Meisam Valizadeh Kiamahalleh ◽  
S. Hadi Madani ◽  
Sheng Dai ◽  
Jingxiu Bi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Stem Cell ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Cartilage Tissue ◽  
Stem Cell Culture ◽  
Chitosan Scaffold ◽  
And Cartilage

scholarly journals Mechanical loading inhibits hypertrophy in chondrogenically differentiating hMSCs within a biomimetic hydrogel

2016 ◽  
Vol 4 (20) ◽  
pp. 3562-3574 ◽  
Author(s):  
E. A. Aisenbrey ◽  
S. J. Bryant
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Mechanical Loading ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Cartilage Tissue

Three dimensional hydrogels are a promising vehicle for delivery of adult human bone-marrow derived mesenchymal stem cells (hMSCs) for cartilage tissue engineering.

scholarly journals In vitro cartilage tissue engineering with different types of collagen porous scaffolds and human bone marrow mesenchymal stem cells

2012 ◽  
Vol 20 ◽  
pp. S279
Author(s):  
S. Díaz-Prado ◽  
E. Muiños-López ◽  
T. Hermida-Gómez ◽  
I. Fuentes-Boquete ◽  
J. Buján ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Porous Scaffolds ◽  
Different Types ◽  
Marrow Mesenchymal Stem Cells

scholarly journals Three-Dimensional Printing Strategies for Irregularly Shaped Cartilage Tissue Engineering: Current State and Challenges

2022 ◽  
Vol 9 ◽  
Author(s):  
Hui Wang ◽  
Zhonghan Wang ◽  
He Liu ◽  
Jiaqi Liu ◽  
Ronghang Li ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Cartilage Tissue ◽  
Future Research ◽  
Engineering Construction ◽  
Three Dimensional Printing ◽  
Current State ◽  
Dimensional Printing

Although there have been remarkable advances in cartilage tissue engineering, construction of irregularly shaped cartilage, including auricular, nasal, tracheal, and meniscus cartilages, remains challenging because of the difficulty in reproducing its precise structure and specific function. Among the advanced fabrication methods, three-dimensional (3D) printing technology offers great potential for achieving shape imitation and bionic performance in cartilage tissue engineering. This review discusses requirements for 3D printing of various irregularly shaped cartilage tissues, as well as selection of appropriate printing materials and seed cells. Current advances in 3D printing of irregularly shaped cartilage are also highlighted. Finally, developments in various types of cartilage tissue are described. This review is intended to provide guidance for future research in tissue engineering of irregularly shaped cartilage.

Collagen-alginate as bioink for three-dimensional (3D) cell printing based cartilage tissue engineering

2018 ◽  
Vol 83 ◽  
pp. 195-201 ◽  
Author(s):  
Xingchen Yang ◽  
Zhenhui Lu ◽  
Huayu Wu ◽  
Wei Li ◽  
Li Zheng ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Cartilage Tissue ◽  
Cell Printing

scholarly journals Chondrocyte Spheroids Laden in GelMA/HAMA Hybrid Hydrogel for Tissue-Engineered Cartilage with Enhanced Proliferation, Better Phenotype Maintenance, and Natural Morphological Structure

Gels ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. 247
Author(s):  
Guanhuier Wang ◽  
Yang An ◽  
Xinling Zhang ◽  
Pengbing Ding ◽  
Hongsen Bi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Proliferation ◽  
Cartilage Tissue Engineering ◽  
Three Dimensional ◽  
Morphological Structure ◽  
Research Direction ◽  
Cartilage Tissue ◽  
Hybrid Hydrogel

Three-dimensional cell-laden tissue engineering has become an extensive research direction. This study aimed to evaluate whether chondrocyte spheroids (chondro-spheroids) prepared using the hanging-drop method could develop better cell proliferation and morphology maintenance characteristics, and be optimized as a micro unit for cartilage tissue engineering. Chondro-spheroids were loaded into a cross-linkable hybrid hydrogel of gelatin methacrylate (GelMA) and hyaluronic acid methacrylate (HAMA) in vivo and in vitro. Cell proliferation, aggregation, cell morphology maintenance as well as cartilage-related gene expression and matrix secretion in vitro and in vivo were evaluated. The results indicated that compared with chondrocyte-laden hydrogel, chondro-spheroid-laden hydrogel enhanced proliferation, had better phenotype maintenance, and a more natural morphological structure, which made it appropriate for use as a micro unit in cartilage tissue engineering.

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