β-Cyclodextrin Nanosponge Hydrogels as Drug Delivery Nanoarchitectonics for Multistep Drug Release Kinetics

Author(s):  
Roberto Vittorio Pivato ◽  
Filippo Rossi ◽  
Monica Ferro ◽  
Franca Castiglione ◽  
Francesco Trotta ◽  
...  
2015 ◽  
Vol 3 (37) ◽  
pp. 7449-7456 ◽  
Author(s):  
Xiang Li ◽  
Qiuhong Zhang ◽  
Zeeshan Ahmad ◽  
Jie Huang ◽  
Zhaohui Ren ◽  
...  

Nd3+ doped CaTiO3 nanostructures serve as a promising drug delivery platform with the potential to monitor drug release kinetics by detecting the tissue-penetrating NIR emission.


2009 ◽  
Vol 26 (4) ◽  
pp. 287-296 ◽  
Author(s):  
Rakesh Kumar Tekade ◽  
Tathagata Dutta ◽  
Virendra Gajbhiye ◽  
Narendra Kumar Jain

2012 ◽  
Vol 584 ◽  
pp. 465-469 ◽  
Author(s):  
S. Malathi ◽  
S. Balasubramanian

Nanoparticles-based drug delivery systems have considerable potential for the treatment of tuberculosis (TB). A series of PLGA polymers with different molar feed ratios (P2:87/13, P3:83/17, P5:63/37, P6:76/24, P9:53/47) were synthesized by direct melt poly condensation method. The resulting biodegradable polymers were characterized by FTIR and 1H NMR spectroscopy. The preparation of the drug (Pyrazinamide (PZA)) encapsulated PLGA polymers were carried out by double emulsion – solvent evaporation technique. The drug loaded PLGA-NPs were analyzed by UV-visible spectroscopy and scanning electron microscopy. The drug loading efficiency and drug release kinetics varies in the following order: P9>P5>P6>P3>P2. Among the formulations, PP9 showed a uniform as well as sustained drug release. The drug release kinetics has been evaluated by Zero-order, First order, Higuchi and Koresmeyer- Peppas models and the release mechanism has also been investigated


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