Reconstitution of Enzymatic Carbon–Sulfur Bond Formation Reveals Detoxification-Like Strategy in Fungal Toxin Biosynthesis

Abstract A Cu(II)-catalyzed Csp2-Se and Csp2-Sulfur bond formation was achieved with moderate to good yields without the aid of Lewis acid and base. The reaction is compatible with a wide range of heterocycles such as benzothiazole, thiazole, and imidazole. Also, this typical protocol is found to be active in thio-selenation via S-H activation. Additionally, we proposed a plausible mechanistic pathway involving Cu(III) putative intermediate.

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Synthesis of quinoline based [1,2,4]-dithiazolidines through sulfur-sulfur bond formation and their evaluation as anti-inflammatory and antibacterial agents

Phosphorus Sulfur and Silicon and the Related Elements ◽

10.1080/10426507.2015.1100179 ◽

2016 ◽

Vol 191 (2) ◽

pp. 254-258

Author(s):

Spruha A. Gharad ◽

Baliram N. Berad ◽

Snehal A. Chavan

Keyword(s):

Antibacterial Agents ◽

Bond Formation ◽

Anti Inflammatory ◽

Sulfur Bond

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Phosphine-Catalyzed Carbon-Sulfur Bond Formation

Synfacts ◽

10.1055/s-0029-1219995 ◽

2010 ◽

Vol 2010 (06) ◽

pp. 0719-0719

Keyword(s):

Bond Formation ◽

Sulfur Bond

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Direct Synthesis of Diverse 2-Aminobenzo[b]thiophenes via Palladium-Catalyzed Carbon–Sulfur Bond Formation Using Na2S2O3 as the Sulfur Source

Organic Letters ◽

10.1021/ol502381e ◽

2014 ◽

Vol 16 (19) ◽

pp. 5040-5043 ◽

Cited By ~ 32

Author(s):

Chuanwei Hou ◽

Qian He ◽

Chunhao Yang

Keyword(s):

Direct Synthesis ◽

Bond Formation ◽

Sulfur Source ◽

Palladium Catalyzed ◽

Sulfur Bond

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Nano-Structured Metal Chalcogenides as Reagents for the Catalytic Carbon–Sulfur Bond Formation in Cross-Coupling Reaction

Topics in Catalysis ◽

10.1007/s11244-013-0091-5 ◽

2013 ◽

Vol 56 (13-14) ◽

pp. 1246-1252 ◽

Cited By ~ 6

Author(s):

Alexey S. Kashin ◽

Valentine P. Ananikov

Keyword(s):

Bond Formation ◽

Coupling Reaction ◽

Cross Coupling ◽

Metal Chalcogenides ◽

Cross Coupling Reaction ◽

Sulfur Bond

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Carbon–sulfur bond formation by reductive elimination of gold(iii) thiolates

Dalton Transactions ◽

10.1039/c8dt00906f ◽

2018 ◽

Vol 47 (18) ◽

pp. 6333-6343 ◽

Cited By ~ 16

Author(s):

Lucy Currie ◽

Luca Rocchigiani ◽

David L. Hughes ◽

Manfred Bochmann

Keyword(s):

Bond Formation ◽

Reductive Elimination ◽

Pincer Complexes ◽

Elimination Reactions ◽

Sulfur Bond

Thiols were found to cleave Au–C bonds in (C^N^C)gold(iii) pincer complexes and to induce C–S reductive elimination reactions, to give aryl thioethers.

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