Brain Targeting and Aβ Binding Bifunctional Nanoparticles Inhibit Amyloid Protein Aggregation in APP/PS1 Transgenic Mice

2021 ◽  
Author(s):  
Xiancheng Zhang ◽  
Xiaoyu Zhang ◽  
You Li ◽  
Manli Zhong ◽  
Pu Zhao ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Protein Aggregation ◽  
Brain Targeting ◽  
Amyloid Protein

Fundamentals and Exploration of Aggregation-Induced Emission Molecules for Amyloid Protein Aggregation

2021 ◽  
Author(s):  
Yijing Tang ◽  
Dong Zhang ◽  
Yanxian Zhang ◽  
Yonglan Liu ◽  
Lirong Cai ◽  
...  
Keyword(s):  
Optical Properties ◽  
Protein Aggregation ◽  
Environmental Health ◽  
Amyloid Protein ◽  
Aggregation Induced Emission ◽  
The Past ◽  
Sensing Applications ◽  
Biomolecule Sensing

The past decade has witnessed the growing interest and advances in aggregation-induced emission (AIE) molecules as driven by their unique fluorescence/optical properties in particular sensing applications including biomolecule sensing/detection, environmental/health...

scholarly journals Does deamidation affect inhibitory mechanisms towards amyloid protein aggregation?

2020 ◽  
Vol 56 (68) ◽  
pp. 9787-9790
Author(s):  
Yuko P. Y. Lam ◽  
Cookson K. C. Chiu ◽  
Christopher A. Wootton ◽  
Ian Hands-Portman ◽  
Meng Li ◽  
...  
Keyword(s):  
Protein Aggregation ◽  
Amyloid Protein ◽  
Wild Type ◽  
Site Specific ◽  
Inhibitory Mechanisms ◽  
Specific Inhibitors

A diagram to show the differences between wild-type and deamidated hIAPPs interaction with site specific and non-specific inhibitors.

NMDA and AMPA Receptors in Transgenic Mice Expressing Humanβ-Amyloid Protein

1993 ◽  
Vol 61 (6) ◽  
pp. 2286-2289 ◽  
Author(s):  
Faheem A. Sandhu ◽  
Richard H. P. Porter ◽  
Robert V. Eller ◽  
Sayeeda B. Zain ◽  
Mohammad Salim ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Ampa Receptors ◽  
Amyloid Protein

scholarly journals Astroglial Expression of Human α1-Antichymotrypsin Enhances Alzheimer-like Pathology in Amyloid Protein Precursor Transgenic Mice

2000 ◽  
Vol 157 (6) ◽  
pp. 2003-2010 ◽  
Author(s):  
Lennart Mucke ◽  
Gui-Qiu Yu ◽  
Lisa McConlogue ◽  
Edward M. Rockenstein ◽  
Carmela R. Abraham ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Protein ◽  
Protein Precursor ◽  
Amyloid Protein Precursor

scholarly journals Mass Spectrometry-Based Screening for Inhibitors of β-Amyloid Protein Aggregation

2005 ◽  
Vol 77 (21) ◽  
pp. 7012-7015 ◽  
Author(s):  
Xun Cheng ◽  
Richard B. van Breemen
Keyword(s):  
Mass Spectrometry ◽  
Protein Aggregation ◽  
Amyloid Protein ◽  
Β Amyloid

β-Amyloid Protein Aggregation

2007 ◽  
pp. 203-225 ◽  
Author(s):  
Marcus A. Etienne ◽  
Nadia J. Edwin ◽  
Jed P. Aucoin ◽  
Paul S. Russo ◽  
Robin L. McCarley ◽  
...  
Keyword(s):  
Protein Aggregation ◽  
Amyloid Protein ◽  
Β Amyloid
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