Backbone dynamics of a model membrane protein: assignment of the carbonyl carbon carbon-13 NMR resonances in detergent-solubilized M13 coat protein

Biochemistry ◽  
1987 ◽  
Vol 26 (12) ◽  
pp. 3619-3626 ◽  
Author(s):  
Gillian D. Henry ◽  
Joel H. Weiner ◽  
Brian D. Sykes
Keyword(s):  
Coat Protein ◽  
Membrane Protein ◽  
Model Membrane ◽  
Backbone Dynamics ◽  
Carbonyl Carbon ◽  
Protein Assignment

scholarly journals Computer simulation of the phase behavior of a model membrane protein: Annexin V

2002 ◽  
Vol 116 (16) ◽  
pp. 7217-7224 ◽  
Author(s):  
Martin A. Bates ◽  
Massimo G. Noro ◽  
Daan Frenkel
Keyword(s):  
Computer Simulation ◽  
Membrane Protein ◽  
Phase Behavior ◽  
Annexin V ◽  
Model Membrane

scholarly journals Direct Interaction of YidC with the Sec-independent Pf3 Coat Protein during Its Membrane Protein Insertion

2001 ◽  
Vol 277 (10) ◽  
pp. 7670-7675 ◽  
Author(s):  
Minyong Chen ◽  
James C. Samuelson ◽  
Fenglei Jiang ◽  
Matthias Muller ◽  
Andreas Kuhn ◽  
...  
Keyword(s):  
Coat Protein ◽  
Membrane Protein ◽  
Direct Interaction ◽  
Protein Insertion ◽  
Membrane Protein Insertion

Interaction of drugs with a model membrane protein

1982 ◽  
Vol 31 (4) ◽  
pp. 527-534 ◽  
Author(s):  
Michael A. Singer
Keyword(s):  
Membrane Protein ◽  
Model Membrane

scholarly journals Assembly of Model Membrane Nanodiscs for Native Mass Spectrometry

2021 ◽  
Author(s):  
Marius Kostelic ◽  
Ciara K. Zak ◽  
Hiruni Jayasekera ◽  
Michael Marty
Keyword(s):  
Mass Spectrometry ◽  
Membrane Protein ◽  
Lipid Bilayers ◽  
Biological Membranes ◽  
Native Mass Spectrometry ◽  
Model Membrane ◽  
Peptide Interactions ◽  
Lipid Nanodiscs ◽  
Natural Lipid ◽  
Selection Of

Native mass spectrometry (MS) with nanodiscs is a promising technique for characterizing membrane protein and peptide interactions in lipid bilayers. However, prior studies have used nanodiscs made of only one or two lipids, which lack the complexity of a natural lipid bilayer. To better model specific biological membranes, we developed model mammalian, bacterial, and mitochondrial nanodiscs with up to four different phospholipids. Careful selection of lipids with similar masses that balance the fluidity and curvature enabled these complex nanodiscs to be assembled and resolved with native MS. We then applied this approach to characterize the specificity and incorporation of LL-37, a human antimicrobial peptide, in single lipid nanodiscs versus model bacterial nanodiscs. Overall, development of these model membrane nanodiscs reveals new insights into the assembly of complex nanodiscs and provides a useful toolkit for studying membrane protein, peptide, and lipid interactions in model biological membranes.

Interaction of drugs with a model membrane protein

1980 ◽  
Vol 29 (19) ◽  
pp. 2651-2655 ◽  
Author(s):  
Michael A. Singer
Keyword(s):  
Membrane Protein ◽  
Model Membrane
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