Transmembrane Helix 11 of Multidrug Resistance Protein 1 (MRP1/ABCC1):  Identification of Polar Amino Acids Important for Substrate Specificity and Binding of ATP at Nucleotide Binding Domain 1†

Biochemistry ◽  
2004 ◽  
Vol 43 (29) ◽  
pp. 9413-9425 ◽  
Author(s):  
Da-Wei Zhang ◽  
Kenichi Nunoya ◽  
Monika Vasa ◽  
Hong-Mei Gu ◽  
Ashley Theis ◽  
...  
Keyword(s):  
Amino Acids ◽  
Multidrug Resistance ◽  
Substrate Specificity ◽  
Transmembrane Helix ◽  
Nucleotide Binding ◽  
Multidrug Resistance Protein ◽  
Nucleotide Binding Domain ◽  
Multidrug Resistance Protein 1 ◽  
Resistance Protein ◽  
Nucleotide Binding Domain 1

Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 bound to Mg2+/ATP Reveals a Non-productive Catalytic Site

2006 ◽  
Vol 359 (4) ◽  
pp. 940-949 ◽  
Author(s):  
Odile Ramaen ◽  
Nicolas Leulliot ◽  
Christina Sizun ◽  
Nathalie Ulryck ◽  
Olivier Pamlard ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Nucleotide Binding ◽  
Catalytic Site ◽  
Binding Domain ◽  
Multidrug Resistance Protein ◽  
Nucleotide Binding Domain ◽  
Multidrug Resistance Protein 1 ◽  
Resistance Protein ◽  
Nucleotide Binding Domain 1

Magnesium dependent complexation of tri-anionic calix[4]arene detergents by the nucleotide binding domain 1 (NBD1) of multidrug resistance protein MRP1

2010 ◽  
Vol 34 (9) ◽  
pp. 1812 ◽  
Author(s):  
Laurent F. A. Nault ◽  
Celine Girardot ◽  
Antoine Leydier ◽  
Anthony W. Coleman ◽  
Thomas Perrotton ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Nucleotide Binding ◽  
Binding Domain ◽  
Multidrug Resistance Protein ◽  
Nucleotide Binding Domain ◽  
Resistance Protein ◽  
Nucleotide Binding Domain 1

Functional Interactions Between Nucleotide Binding Domains and Leukotriene C4 Binding Sites of Multidrug Resistance Protein 1 (ABCC1)

2005 ◽  
Vol 67 (6) ◽  
pp. 1944-1953 ◽  
Author(s):  
Lea Payen ◽  
Mian Gao ◽  
Christopher Westlake ◽  
Ashley Theis ◽  
Susan P. C. Cole ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Binding Sites ◽  
Nucleotide Binding ◽  
Multidrug Resistance Protein ◽  
Leukotriene C4 ◽  
Multidrug Resistance Protein 1 ◽  
Functional Interactions ◽  
Binding Domains ◽  
Resistance Protein

scholarly journals An Outward-Facing Aromatic Amino Acid Is Crucial for Signaling between the Membrane-Spanning and Nucleotide-Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1)

2018 ◽  
Vol 94 (3) ◽  
pp. 1069-1078 ◽  
Author(s):  
Kevin E. Weigl ◽  
Gwenaëlle Conseil ◽  
Alice J. Rothnie ◽  
May Arama ◽  
Yossi Tsfadia ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Amino Acid ◽  
Aromatic Amino Acid ◽  
Nucleotide Binding ◽  
Multidrug Resistance Protein ◽  
Multidrug Resistance Protein 1 ◽  
Binding Domains ◽  
Resistance Protein ◽  
Membrane Spanning

scholarly journals Comparison of the Functional Characteristics of the Nucleotide Binding Domains of Multidrug Resistance Protein 1

2000 ◽  
Vol 275 (17) ◽  
pp. 13098-13108 ◽  
Author(s):  
Mian Gao ◽  
Heng-Ran Cui ◽  
Douglas W. Loe ◽  
Caroline E. Grant ◽  
Kurt C. Almquist ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Nucleotide Binding ◽  
Multidrug Resistance Protein ◽  
Functional Characteristics ◽  
Multidrug Resistance Protein 1 ◽  
Binding Domains ◽  
Resistance Protein

scholarly journals Determinants of the Substrate Specificity of Multidrug Resistance Protein 1

2002 ◽  
Vol 277 (23) ◽  
pp. 20934-20941 ◽  
Author(s):  
Da-Wei Zhang ◽  
Susan P. C. Cole ◽  
Roger G. Deeley
Keyword(s):  
Multidrug Resistance ◽  
Substrate Specificity ◽  
Multidrug Resistance Protein ◽  
Multidrug Resistance Protein 1 ◽  
Resistance Protein
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