Thermodynamics of a Transition State Analogue Inhibitor Binding toEscherichia coliChorismate Mutase:  Probing the Charge State of an Active Site Residue and Its Role in Inhibitor Binding and Catalysis†,‡

Biochemistry ◽  
1998 ◽  
Vol 37 (25) ◽  
pp. 9052-9057 ◽  
Author(s):  
Angela Y. Lee ◽  
Sheng Zhang ◽  
Palangpon Kongsaeree ◽  
Jon Clardy ◽  
Bruce Ganem ◽  
...  
Keyword(s):  
Transition State ◽  
Charge State ◽  
Active Site ◽  
Active Site Residue ◽  
Inhibitor Binding ◽  
Transition State Analogue

scholarly journals A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site

2006 ◽  
Vol 103 (40) ◽  
pp. 14732-14737 ◽  
Author(s):  
N. J. Baxter ◽  
L. F. Olguin ◽  
M. Golicnik ◽  
G. Feng ◽  
A. M. Hounslow ◽  
...  
Keyword(s):  
Transition State ◽  
Active Site ◽  
Trojan Horse ◽  
Enzyme Active Site ◽  
Transition State Analogue

On a Possible Neutral Charge State for the Catalytic Dyad in β-Secretase When Bound to Hydroxyethylene Transition State Analogue Inhibitors

2011 ◽  
Vol 54 (8) ◽  
pp. 3081-3085 ◽  
Author(s):  
Fredy Sussman ◽  
José M. Otero ◽  
M. Carmen Villaverde ◽  
Marian Castro ◽  
José L. Domínguez ◽  
...  
Keyword(s):  
Transition State ◽  
Charge State ◽  
Transition State Analogue ◽  
Transition State Analogue Inhibitors ◽  
Catalytic Dyad ◽  
Neutral Charge State

MgF3−and α-Galactose 1-Phosphate in the Active Site of β-Phosphoglucomutase Form a Transition State Analogue of Phosphoryl Transfer

2009 ◽  
Vol 131 (45) ◽  
pp. 16334-16335 ◽  
Author(s):  
Nicola J. Baxter ◽  
Andrea M. Hounslow ◽  
Matthew W. Bowler ◽  
Nicholas H. Williams ◽  
G. Michael Blackburn ◽  
...  
Keyword(s):  
Transition State ◽  
Active Site ◽  
Phosphoryl Transfer ◽  
Transition State Analogue
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