Immunochemical Studies on Blood Groups.1XXIV. Some Oligosaccharides Isolated from Dialysates After Mild Acid Hydrolysis of Human Blood Group B Substances from Ovarian Cyst Fluid

1960 ◽  
Vol 82 (5) ◽  
pp. 1122-1127 ◽  
Author(s):  
Gerald Schiffman ◽  
Elvin A. Kabat ◽  
Sidney Leskowitz
1971 ◽  
Vol 133 (1) ◽  
pp. 39-52 ◽  
Author(s):  
Ten Feizi ◽  
Elvin A. Kabat ◽  
Giuseppe Vicari ◽  
Byron Anderson ◽  
W. Laurence Marsh

A partially purified blood group-like substance obtained from milk showed I activity with 2 of 21 anti-I sera. With these antisera, certain human ovarian cyst substances considered to be precursors of the A, B, H, Lea, and Leb substances also showed I activity comparable to the milk material. Strong I activity could be produced by one-stage periodate oxidation and Smith degradation of human ovarian cyst A and B substances, or of hog mucin A + H substance, or by mild acid hydrolysis of human saliva or ovarian cyst blood group B substance. The two sera indicate that I specificity appears at intermediate stages in the biosynthesis of the A, B, H, Lea, and Lea substances. Anti-I sera differ strikingly in their specificities, indicating substantial heterogeneity of the I determinants.


2003 ◽  
Vol 278 (14) ◽  
pp. 12403-12405 ◽  
Author(s):  
Sandra L. Marcus ◽  
Robert Polakowski ◽  
Nina O. L. Seto ◽  
Eeva Leinala ◽  
Svetlana Borisova ◽  
...  

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