Crystal Structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in Complex with the 20S Proteasome Reveal Important Consequences of β-Lactone Ring Opening and a Mechanism for Irreversible Binding

2006 ◽  
Vol 128 (15) ◽  
pp. 5136-5141 ◽  
Author(s):  
Michael Groll ◽  
Robert Huber ◽  
Barbara C. M. Potts
Keyword(s):  
Crystal Structures ◽  
Ring Opening ◽  
Lactone Ring ◽  
20S Proteasome ◽  
Irreversible Binding ◽  
Salinosporamide A

scholarly journals New Coordination Modes for Modified Schiff Base Ti(IV) Complexes and Their Control over Lactone Ring-Opening Polymerization Activity

2018 ◽  
Vol 57 (22) ◽  
pp. 14240-14248 ◽  
Author(s):  
Christopher B. Durr ◽  
Charlotte K. Williams
Keyword(s):  
Schiff Base ◽  
Ring Opening ◽  
Lactone Ring ◽  
Ring Opening Polymerization ◽  
Coordination Modes

scholarly journals Controlled Random Terpolymerization of β-Propiolactone, Epoxides, and CO 2 via Regioselective Lactone Ring Opening

CCS Chemistry ◽  
2021 ◽  
pp. 1-24
Author(s):  
Wen-Bing Li ◽  
Bai-Hao Ren ◽  
Ge-Ge Gu ◽  
Xiao-Bing Lu
Keyword(s):  
Ring Opening ◽  
Lactone Ring

Polyester from dimethylketene and acetaldehyde: Direct copolymerization and β-lactone ring-opening polymerization

2011 ◽  
Vol 49 (19) ◽  
pp. 4129-4138 ◽  
Author(s):  
Marc Brestaz ◽  
Nicolas Desilles ◽  
Guillaume Le ◽  
Claude Bunel
Keyword(s):  
Ring Opening ◽  
Lactone Ring ◽  
Ring Opening Polymerization

Total Synthesis of Olivacine and Ellipticine via a Lactone Ring-Opening and Aromatization Cascade

2019 ◽  
Vol 84 (12) ◽  
pp. 7901-7916 ◽  
Author(s):  
Ömer Dilek ◽  
Süleyman Patir ◽  
Tahir Tilki ◽  
Erkan Ertürk
Keyword(s):  
Total Synthesis ◽  
Ring Opening ◽  
Lactone Ring

Synthesis of Salinosporamide A and Its Analogs as 20S Proteasome Inhibitors and SAR Summarization

2011 ◽  
Vol 11 (23) ◽  
pp. 2906-2922 ◽  
Author(s):  
Yuheng Ma ◽  
Lili Qu ◽  
Zhenming Liu ◽  
Liangren Zhang ◽  
Zhenjun Yang ◽  
...  
Keyword(s):  
Proteasome Inhibitors ◽  
20S Proteasome ◽  
Salinosporamide A

Formation of L‐Threonic Acid from L‐Ascorbic Acid Oxidative Ring Opening and its Coordination to PtII: X‐ray Crystal Structures of [Pt(threonato‐O,O′)(PPh3)2] and [Pt(oxalato)(PPh3)2]

2008 ◽  
Vol 2008 (19) ◽  
pp. 3056-3061 ◽  
Author(s):  
Paola Bergamini ◽  
Elena Marchesi ◽  
Andrea Marchi ◽  
Valerio Bertolasi ◽  
Marco Fogagnolo ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Crystal Structures ◽  
Ring Opening ◽  
X Ray ◽  
Threonic Acid

Synthesis, Structures, and Conformations of Linked Bis-Glyoxylamides Derived from Bis-Acylisatins

2014 ◽  
Vol 67 (9) ◽  
pp. 1270 ◽  
Author(s):  
Venty Suryanti ◽  
Glenn C. Condie ◽  
Mohan Bhadbhade ◽  
Roger Bishop ◽  
David StC. Black ◽  
...  
Keyword(s):  
Amino Acid ◽  
Crystal Structures ◽  
Intermolecular Interactions ◽  
Ring Opening ◽  
Alkyl Esters ◽  
Alkyl Chains

A series of bis-glyoxylamides possessing hydrophobic alkyl chains was successfully synthesised by ring opening of bis-acylisatins with amines or amino acid alkyl esters. The crystal structures revealed the interplay of intra- and intermolecular interactions (NH···O and C=O···C=O interactions) and the conformations of these long molecules.

On the Origin of the Different Reversible Characters of Salinosporamide A and Homosalinosporamide A in the Covalent Inhibition of the Human 20S Proteasome

ACS Catalysis ◽  
2021 ◽  
Vol 11 (18) ◽  
pp. 11806-11819
Author(s):  
Natalia Serrano-Aparicio ◽  
Vicent Moliner ◽  
Katarzyna Świderek
Keyword(s):  
20S Proteasome ◽  
Salinosporamide A ◽  
Covalent Inhibition

Formation of Reactant Complex Structure for Initiation Reaction of Lactone Ring-Opening Polymerization by Cooperation of Multiple Cyclodextrin

2016 ◽  
Vol 120 (29) ◽  
pp. 7174-7181 ◽  
Author(s):  
Masayoshi Takayanagi ◽  
Shoko Ito ◽  
Kentaro Matsumoto ◽  
Masataka Nagaoka
Keyword(s):  
Ring Opening ◽  
Lactone Ring ◽  
Complex Structure ◽  
Ring Opening Polymerization ◽  
Initiation Reaction
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