Stereodynamic Chemosensor with Selective Circular Dichroism and Fluorescence Readout for in Situ Determination of Absolute Configuration, Enantiomeric Excess, and Concentration of Chiral Compounds

2013 ◽  
Vol 135 (33) ◽  
pp. 12200-12203 ◽  
Author(s):  
Keith W. Bentley ◽  
Christian Wolf
Keyword(s):  
Circular Dichroism ◽  
Absolute Configuration ◽  
Enantiomeric Excess ◽  
Chiral Compounds ◽  
Determination Of Absolute Configuration ◽  
Circular Dichroïsm

(-)-Strempeliopine, stereoselective total synthesis and the determination of absolute configuration

1986 ◽  
Vol 51 (8) ◽  
pp. 1731-1742 ◽  
Author(s):  
Josef Hájíček ◽  
Jan Trojánek
Keyword(s):  
Circular Dichroism ◽  
Total Synthesis ◽  
Absolute Configuration ◽  
Determination Of Absolute Configuration ◽  
Natural Base ◽  
The Absolute ◽  
Circular Dichroïsm

A synthesis of (±)-strempeliopine (II) is described, the key step of which is the stereoselective reductive rearrangement of 18-methylene-1,2-dehydroaspidospermidine (XI). The absolute configuration of the natural (-)-base II was determined as (2S, 7R, 20R, 21R) on the basis of its synthesis from (+)-18-methylenevincadifformine (XVII) the configuration of which was derived from a comparison of circular dichroism properties of bases with a β-anilinoacrylate chromophore. The biogenesis of the alkaloids of the schizozygane type is discussed.

scholarly journals In Situ Assembly of Octahedral Fe(II) Complexes for the Enantiomeric Excess Determination of Chiral Amines Using Circular Dichroism Spectroscopy

2012 ◽  
Vol 134 (9) ◽  
pp. 4398-4407 ◽  
Author(s):  
Justin M. Dragna ◽  
Gennaro Pescitelli ◽  
Lee Tran ◽  
Vincent M. Lynch ◽  
Eric V. Anslyn ◽  
...  
Keyword(s):  
Circular Dichroism ◽  
Enantiomeric Excess ◽  
Circular Dichroism Spectroscopy ◽  
Chiral Amines ◽  
Circular Dichroïsm
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