scholarly journals Nanoscale Metal–Organic Framework for Highly Effective Photodynamic Therapy of Resistant Head and Neck Cancer

2014 ◽  
Vol 136 (48) ◽  
pp. 16712-16715 ◽  
Author(s):  
Kuangda Lu ◽  
Chunbai He ◽  
Wenbin Lin
Keyword(s):  
Head And Neck Cancer ◽  
Photodynamic Therapy ◽  
Head And Neck ◽  
Neck Cancer ◽  
Metal Organic Framework ◽  
Highly Effective ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Dual-mode humidity detection using a lanthanide-based metal–organic framework: towards multifunctional humidity sensors

2017 ◽  
Vol 53 (32) ◽  
pp. 4465-4468 ◽  
Author(s):  
Yuan Gao ◽  
Pengtao Jing ◽  
Ning Yan ◽  
Michiel Hilbers ◽  
Hong Zhang ◽  
...  
Keyword(s):  
Impedance Spectroscopy ◽  
Humidity Sensor ◽  
Metal Organic Framework ◽  
Dual Mode ◽  
Humidity Sensors ◽  
Highly Effective ◽  
Metal Organic ◽  
Spectroscopy Studies ◽  
Organic Framework

Combined photoluminescence and impedance spectroscopy studies show that a europium-based metal–organic framework behaves as a highly effective and reliable humidity sensor, enabling dual-mode humidity detection.

scholarly journals EGFR targeted nanobody–photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer

2016 ◽  
Vol 229 ◽  
pp. 93-105 ◽  
Author(s):  
Pieter B.A.A. van Driel ◽  
Martin C. Boonstra ◽  
Maxime D. Slooter ◽  
Raimond Heukers ◽  
Marieke A. Stammes ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Photodynamic Therapy ◽  
Head And Neck ◽  
Neck Cancer ◽  
Clinical Model

Rational fabrication of two-photon responsive metal-organic framework for enhanced photodynamic therapy

2021 ◽  
Author(s):  
Xin Yao ◽  
Xinxin Pei ◽  
Bo Li ◽  
Mengqi Lv ◽  
Wen Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Side Effects ◽  
Rational Design ◽  
Metal Organic Framework ◽  
Cancer Treatments ◽  
Two Photon ◽  
Metal Organic ◽  
Organic Framework

Rational design of specific platform which can address the unavoidable side effects of traditional cancer treatments is of great interest. In this sense, herein, an intelligent nanoplatform (ZnL1@MOF-199@FA) with efficient...

scholarly journals Metal-Organic Framework Combined with CaO2 Nanoparticles for Enhanced and Targeted Photodynamic Therapy

2021 ◽  
Author(s):  
Xinran Sun ◽  
Kaixiu Chen ◽  
Ying-Yan Liu ◽  
Guoda Zhang ◽  
Min Shi ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Therapeutic Approach ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Targeted Photodynamic Therapy ◽  
Organic Framework

Photodynamic therapy (PDT) has been rapidly developing an effective therapeutic approach in clinical. However, hypoxia seriously limits the effectiveness of PDT. Here, we report a porphyrinic based metal-organic framework combined...

scholarly journals Treatment of head and neck cancer with photodynamic therapy: results after one year

1995 ◽  
Vol 109 (11) ◽  
pp. 1072-1076 ◽  
Author(s):  
M. G. Dtlkes ◽  
M. L. DeJode ◽  
Q. Gardiner ◽  
G. S. Kenyon ◽  
P. McKelvie
Keyword(s):  
Head And Neck Cancer ◽  
Photodynamic Therapy ◽  
Head And Neck ◽  
Neck Cancer ◽  
First Generation ◽  
Sufficient Evidence ◽  
Clinical Responses ◽  
Promising Treatment ◽  
One Year ◽  
Multicentre Prospective Study

AbstractPhotodynamic therapy (PDT) is a new and promising treatment modality for the treatment of malignant disease. This paper reports the preliminary experience of our group in the use of this therapy for the treatment of tumours arising in the head and neck. The majority of treatments in these cases have used a second generation systemic photosensitizer, meta-tetrahydroxyphenylchlorin (m-THPC). Two other cases were treated with either Photofrin 2 (a first generation systemic sensitizer) or with the topical photosensitizer, delta-aminolaevulinic acid (δ-ALA).The initial results have been encouraging with good clinical responses evident in patients presenting with a variety of differing tumour types. We feel there is now sufficient evidence of the efficacy of this treatment to warrant a multicentre prospective study into the treatment of early head and neck cancer with PDT.

Mesoporous Rod‐Like Metal‐Organic Framework with Optimal Tumor Targeting Properties for Enhanced Activatable Photodynamic Therapy

2020 ◽  
Vol 3 (7) ◽  
pp. 2000011
Author(s):  
Yuanbo Wang ◽  
Xingang Liu ◽  
Wenbo Wu ◽  
Duo Mao ◽  
Bo Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Targeting ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Optimal Tumor ◽  
Organic Framework

Highly effective and fast removal of anionic carcinogenic dyes via an In3-cluster-based cationic metal–organic framework with nitrogen-rich ligand

2020 ◽  
Vol 4 (1) ◽  
pp. 182-188 ◽  
Author(s):  
Xinyao Liu ◽  
Bing Liu ◽  
Jarrod F. Eubank ◽  
Yunling Liu
Keyword(s):  
Metal Organic Framework ◽  
Organic Ligand ◽  
Organic Dye ◽  
Dye Molecules ◽  
Highly Effective ◽  
Metal Organic ◽  
Rapid Removal ◽  
Fast Removal ◽  
Organic Framework

A novel cationic MOFs (In-TATAB) built by In3-cluster and nitrogen-rich organic ligand with new (3,6)-c topology has been successfully designed and synthesized. It shows highly effective and rapid removal of anionic carcinogenic organic dye molecules.

Porphyrin‐Based Metal−Organic Framework Compounds as Promising Nanomedicines in Photodynamic Therapy

ChemMedChem ◽  
2020 ◽  
Vol 15 (19) ◽  
pp. 1766-1775
Author(s):  
Wenmei Yu ◽  
Wenqiang Zhen ◽  
Qizhi Zhang ◽  
Yanchun Li ◽  
Hongyu Luo ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Framework Compounds ◽  
Organic Framework

Solvent-Assisted Self-Assembly of a Metal–Organic Framework Based Biocatalyst for Cascade Reaction Driven Photodynamic Therapy

2020 ◽  
Vol 142 (14) ◽  
pp. 6822-6832 ◽  
Author(s):  
Liangcan He ◽  
Qianqian Ni ◽  
Jing Mu ◽  
Wenpei Fan ◽  
Lu Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Self Assembly ◽  
Metal Organic Framework ◽  
Cascade Reaction ◽  
Metal Organic ◽  
Organic Framework
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