Site-Selective 1,1-Difunctionalization of Unactivated Alkenes Enabled by Cationic Palladium Catalysis

2019 ◽  
Vol 141 (25) ◽  
pp. 10048-10059 ◽  
Author(s):  
Jinwon Jeon ◽  
Ho Ryu ◽  
Changseok Lee ◽  
Dasol Cho ◽  
Mu-Hyun Baik ◽  
...  
Keyword(s):  
Palladium Catalysis ◽  
Site Selective ◽  
Cationic Palladium

Site-Selective Aerobic C–H Monoacylation of Carbazoles Using Palladium Catalysis

2020 ◽  
Author(s):  
Subhadip Maiti ◽  
Tirtha Mandal ◽  
Barada Prasanna Dash ◽  
Jyotirmayee Dash
Keyword(s):  
Palladium Catalysis ◽  
Site Selective

scholarly journals External oxidant-compatible phosphorus(III)-directed site-selective C–H carbonylation

2020 ◽  
Vol 6 (51) ◽  
pp. eabd1378
Author(s):  
Ben Dong ◽  
Jiasheng Qian ◽  
Mingjie Li ◽  
Zheng-Jun Wang ◽  
Minyan Wang ◽  
...  
Keyword(s):  
Palladium Catalysis ◽  
High Reactivity ◽  
X Ray ◽  
Compatible System ◽  
Directing Group ◽  
Positional Selectivity ◽  
Site Selective ◽  
Selection Of

The first development of an external oxidant-compatible system involving a phosphorus(III)-directed C–H functionalization has been uncovered. An efficient C–H esterification of indoles with CO and alcohols has been reported in which the high reactivity and the exclusive C7-selectivity derives from the selection of a P(III)–directing group and the utilization of benzoquinone as an external oxidant with palladium catalysis. This strategy shows many advantages, involving an easily accessible and removable directing group, the use of cheap carbonylation sources, a broad substrate scope, and excellent positional selectivity. Two cyclopalladated intermediates were confirmed by x-ray analysis, uncovering key mechanistic features of this P(III)-directed C–H metalation event.

scholarly journals Regioselective B(3,4)–H arylation of o-carboranes by weak amide coordination at room temperature

2020 ◽  
Vol 11 (39) ◽  
pp. 10764-10769 ◽  
Author(s):  
Yu-Feng Liang ◽  
Long Yang ◽  
Becky Bongsuiru Jei ◽  
Rositha Kuniyil ◽  
Lutz Ackermann
Keyword(s):  
Room Temperature ◽  
Palladium Catalysis ◽  
Weakly Coordinating ◽  
Site Selective

B–H: site-selective B(3,4)–H arylations were accomplished at room temperature by versatile palladium catalysis enabled by weakly coordinating amides.

ChemInform Abstract: Site-Selective Modification of Peptides Using Rhodium and Palladium Catalysis: Complementary Electrophilic and Nucleophilic Arylation.

ChemInform ◽  
2008 ◽  
Vol 39 (7) ◽  
Author(s):  
Christopher J. Chapman ◽  
Ai Matsuno ◽  
Christopher G. Frost ◽  
Michael C. Willis
Keyword(s):  
Palladium Catalysis ◽  
Site Selective

Predictable and Site-Selective Functionalization of Poly(hetero)arene Compounds by Palladium Catalysis

2011 ◽  
Vol 76 (3) ◽  
pp. 749-759 ◽  
Author(s):  
David Lapointe ◽  
Thomas Markiewicz ◽  
Christopher J. Whipp ◽  
Amy Toderian ◽  
Keith Fagnou
Keyword(s):  
Palladium Catalysis ◽  
Selective Functionalization ◽  
Site Selective

Site-selective modification of peptides using rhodium and palladium catalysis: complementary electrophilic and nucleophilic arylation

2007 ◽  
pp. 3903 ◽  
Author(s):  
Christopher J. Chapman ◽  
Ai Matsuno ◽  
Christopher G. Frost ◽  
Michael C. Willis
Keyword(s):  
Palladium Catalysis ◽  
Site Selective

scholarly journals Palladium-catalyzed ligand-promoted site-selective cyanomethylation of unactivated C(sp3)–H bonds with acetonitrile

2016 ◽  
Vol 7 (4) ◽  
pp. 2804-2808 ◽  
Author(s):  
Yongbing Liu ◽  
Ke Yang ◽  
Haibo Ge
Keyword(s):  
Palladium Catalysis ◽  
Direct Coupling ◽  
Palladium Catalyzed ◽  
Site Selective

The direct coupling of unactivated sp3 C–H bonds in aliphatic amides with acetonitrile was achieved via palladium catalysis.

scholarly journals Site-Selective Cross-Coupling of Remote Chlorides Enabled by Electrostatically Directed Palladium Catalysis

2018 ◽  
Vol 140 (42) ◽  
pp. 13570-13574 ◽  
Author(s):  
William A. Golding ◽  
Robert Pearce-Higgins ◽  
Robert J. Phipps
Keyword(s):  
Palladium Catalysis ◽  
Cross Coupling ◽  
Site Selective

Asymmetric Aminoacetoxylation of Nonactivated Alkenes by Palladium Catalysis

Synfacts ◽  
2018 ◽  
Vol 14 (09) ◽  
pp. 0951
Keyword(s):  
Palladium Catalysis
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