Determination of Theaflavins Including Methylated Theaflavins in Black Tea Leaves by Solid-Phase Extraction and HPLC Analysis

2007 ◽  
Vol 55 (18) ◽  
pp. 7252-7257 ◽  
Author(s):  
Masami Nishimura ◽  
Kinuko Ishiyama ◽  
Akiko Watanabe ◽  
Setsuko Kawano ◽  
Toshio Miyase ◽  
...  
Author(s):  
J L Rudy ◽  
J C Argyle ◽  
N Winick ◽  
P Van Dreal

A convenient HPLC assay, which allows for the simultaneous measurement in extracellular fluids of 6-mercaptopurine and four of its metabolites, 6-thioguanine, 6-mercaptopurine riboside, 6-thioxanthine and 6-thiouric acid is described. Solid phase extraction allows for the clean isolation of analytes from plasma, urine or cerebrospinal fluid. The simultaneous determination of 6-mercaptopurine and some of its major metabolites in extracellular fluids may contribute to the monitoring of patient compliance, bioavailability, and individual variation in metabolism and absorption.


2014 ◽  
Vol 62 (22) ◽  
pp. 5220-5225 ◽  
Author(s):  
Cristina Giovannoli ◽  
Cinzia Passini ◽  
Fabio Di Nardo ◽  
Laura Anfossi ◽  
Claudio Baggiani

Sign in / Sign up

Export Citation Format

Share Document