Anticancer Specificity of Some Ellipticinium Salts against Human Brain Tumors in vitro

1994 ◽  
Vol 37 (14) ◽  
pp. 2185-2189 ◽  
Author(s):  
Edward M. Acton ◽  
Ven L. Narayanan ◽  
Prabhakar A. Risbood ◽  
Robert H. Shoemaker ◽  
David T. Vistica ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Human Brain Tumors

Cell kinetics studies of human brain tumors by in vitro labeling using anti-BUdR monoclonal antibody

1988 ◽  
Vol 69 (3) ◽  
pp. 371-374 ◽  
Author(s):  
Takafumi Nishizaki ◽  
Tetsuji Orita ◽  
Masahide Saiki ◽  
Yasuhiro Furutani ◽  
Hideo Aoki
Keyword(s):  
Monoclonal Antibody ◽  
Brain Tumors ◽  
Human Brain ◽  
Intravenous Infusion ◽  
Reproductive Age ◽  
Proliferative Potential ◽  
Human Brain Tumor ◽  
Human Brain Tumors

✓ Since the development of a specific monoclonal antibody against the thymidine analogue bromodeoxyuridine (BUdR), many investigators have used intravenous infusion of BUdR to estimate the proliferative potential of human brain tumors. However, side effects such as the induction of cell mutation, latent virus promotion, or inhibition of cytodifferentiation cannot be ignored, and thus many workers hesitate to use it in patients, especially those with hepatic disease or of reproductive age. Furthermore, if BUdR remains in the deoxyribonucleic acid of tumor cells after injection, analysis of the effect of chemical and radiation therapy may not be evaluated correctly. In this report, in vitro BUdR labeling with an anti-BUdR antibody is compared with the in vivo methods described by previous authors. This method appears to be useful for determining the S-phase fraction of human brain tumor. It was more rapid, and was simple, safe, and reproducible as compared to the intravenous infusion method.

Chemosensitivity of Malignant Human Brain Tumors in vitro

2015 ◽  
pp. 157-166
Author(s):  
R. Sch�nmayr ◽  
J. C. Tonn ◽  
K. H. Link ◽  
H. P. Kraemer
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Human Brain Tumors

In vitro chemosensitivity test of human brain tumors using a three-dimensional organ culture with a collagen gel matrix

1994 ◽  
Vol 21 (3) ◽  
pp. 225-232 ◽  
Author(s):  
Kiyoshi Yuki ◽  
Tohru Uozumi ◽  
Yasunori Kodama ◽  
Kaoru Kurisu ◽  
Takashi Mikami
Keyword(s):  
Brain Tumors ◽  
Organ Culture ◽  
Human Brain ◽  
Three Dimensional ◽  
Collagen Gel ◽  
Chemosensitivity Test ◽  
Human Brain Tumors ◽  
In Vitro Chemosensitivity Test ◽  
Collagen Gel Matrix

In vivo and in vitro NMR of human brain tumors

1997 ◽  
pp. 439-440
Author(s):  
V. Tugnoli ◽  
M. R. Tosi ◽  
A. Bertoluzza ◽  
G. Barbarella ◽  
R. Ricci
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Human Brain Tumors

In vitro terahertz spectroscopy of gelatin-embedded human brain tumors: a pilot study

2018 ◽  
Author(s):  
Kirill I. Zaytsev ◽  
Nikita V. Chernomyrdin ◽  
Arseniy A. Gavdush ◽  
Sheyh-Islyam T. Beshplav ◽  
Kirill M. Malakhov ◽  
...  
Keyword(s):  
Pilot Study ◽  
Brain Tumors ◽  
Human Brain ◽  
Terahertz Spectroscopy ◽  
Human Brain Tumors

scholarly journals A new method for analyzing the cell kinetics of human brain tumors by double labeling with bromodeoxyuridine in situ and with iododeoxyuridine in vitro

Cancer ◽  
1993 ◽  
Vol 71 (10) ◽  
pp. 3109-3113 ◽  
Author(s):  
Makoto Shibuya ◽  
Satoyuki Ito ◽  
Charles B. Wilson ◽  
Takao Hoshino ◽  
Richard L. Davis
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Cell Kinetics ◽  
New Method ◽  
Double Labeling ◽  
Human Brain Tumors ◽  
Kinetics Of

scholarly journals Studies of Human Papovavirus Tumor Antigen in Experimental and Human Cerebral Neoplasms

1976 ◽  
Vol 3 (2) ◽  
pp. 105-109 ◽  
Author(s):  
L.E. Becker ◽  
O. Narayan ◽  
R.T. Johnson
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
T Antigen ◽  
In Vitro Cultivation ◽  
Human Brain Tumors ◽  
Induced Tumors ◽  
Human Papovavirus ◽  
Immunofluorescent Technique ◽  
Cryostat Sections

SUMMARY:Three types of papovaviruses (JC, BK, and SV40) have been isolated from man. All three are oncogenic in hamsters, cause frequent infection of man, and share a common T antigen. Augmentation of the expression of T antigen by in vitro cultivation of SV40-induced tumors of hamsters suggested that growing human brain tumors in vitro might provide an effective screening technique for the SV40 virus. In a series of human brain tumors examined in cryostat sections and in tissue culture, T antigen could not be demonstrated, suggesting that by this immunofluorescent technique SV40 was not implicated in the etiology of these tumors.

In vitro terahertz dielectric spectroscopy of human brain tumors

2018 ◽  
Author(s):  
Kirill I. Zaytsev ◽  
Nikita V. Chernomyrdin ◽  
Kirill M. Malakhov ◽  
Sheyh-Islyam T. Beshplav ◽  
Sergey A. Goryaynov ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Dielectric Spectroscopy ◽  
Human Brain Tumors

Oxidative metabolism and glycolysis in benign brain tumors

1987 ◽  
Vol 67 (3) ◽  
pp. 336-340 ◽  
Author(s):  
Terry Lichtor ◽  
George J. Dohrmann
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Oxidative Metabolism ◽  
Glucose Utilization ◽  
Content Type ◽  
Human Brain Tumors ◽  
Elevated Glucose ◽  
Slow Growing

✓ Glucose utilization in vivo and hexokinase activity and mitochondrial oxygen consumption in vitro were measured in a series of human brain tumors. Several relatively slow-growing tumors appeared to have depressed electron-transport activities coupled with a compensatory elevated glucose utilization. These data suggest that a decrease in oxidative metabolism and a corresponding increase in glycolysis are not necessarily correlated with malignancy in certain human brain tumors.

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