Conformational properties of central nervous system active thyrotropin releasing hormone analogs: probing structure-activity relationships at the molecular level

Journal of Medicinal Chemistry ◽

10.1021/jm00379a022 ◽

1985 ◽

Vol 28 (1) ◽

pp. 125-137 ◽

Author(s):

Emil Eckle ◽

John J. Stezowski

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Molecular Level ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

Structure Activity Relationships ◽

Structure Activity ◽

Conformational Properties ◽

Hormone Analogs

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ChemInform Abstract: CONFORMATIONAL PROPERTIES OF CENTRAL NERVOUS SYSTEM ACTIVE THYROTROPIN RELEASING HORMONE ANALOGS: PROBING STRUCTURE-ACTIVITY RELATIONSHIPS AT THE MOLECULAR LEVEL

Chemischer Informationsdienst ◽

10.1002/chin.198521361 ◽

1985 ◽

Vol 16 (21) ◽

Author(s):

E. ECKLE ◽

J. J. STEZOWSKI

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Molecular Level ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

Structure Activity Relationships ◽

Structure Activity ◽

Conformational Properties ◽

Hormone Analogs

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Synthesis of thyrotropin-releasing hormone analogs with selective central nervous system effects

Journal of Medicinal Chemistry ◽

10.1021/jm00138a010 ◽

1981 ◽

Vol 24 (6) ◽

pp. 692-698 ◽

Author(s):

Ruth F. Nutt ◽

Frederick W. Holly ◽

Carl Homnick ◽

Ralph Hirschmann ◽

Daniel F. Veber ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

Hormone Analogs

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ChemInform Abstract: SYNTHESIS OF THYROTROPIN-RELEASING HORMONE ANALOGS WITH SELECTIVE CENTRAL NERVOUS SYSTEM EFFECTS

Chemischer Informationsdienst ◽

10.1002/chin.198144199 ◽

1981 ◽

Vol 12 (44) ◽

Author(s):

R. F. NUTT ◽

F. W. HOLLY ◽

C. HOMNICK ◽

R. HIRSCHMANN ◽

D. F. VEBER ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

Hormone Analogs

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Synthesis of thyrotropin-releasing hormone analogs. 1. Complete dissociation of central nervous system effects from thyrotropin-releasing activity

Journal of Medicinal Chemistry ◽

10.1021/jm00372a006 ◽

1984 ◽

Vol 27 (6) ◽

pp. 741-745 ◽

Author(s):

Tamas Szirtes ◽

Lajos Kisfaludy ◽

Eva Palosi ◽

Laszlo Szporny

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

Hormone Analogs ◽

Complete Dissociation

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Synthesis of thyrotropin-releasing hormone analogs. 2. Tripeptides structurally greatly different from TRH with high central nervous system activity

Journal of Medicinal Chemistry ◽

10.1021/jm00159a015 ◽

1986 ◽

Vol 29 (9) ◽

pp. 1654-1658 ◽

Author(s):

Tamas Szirtes ◽

Lajos Kisfaludy ◽

Eva Palosi ◽

Laszlo Szporny

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

System Activity ◽

Nervous System Activity ◽

Central Nervous System Activity ◽

Hormone Analogs

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ChemInform Abstract: SYNTHESIS OF THYROTROPIN-RELEASING HORMONE ANALOGS. 1. COMPLETE DISSOCIATION OF CENTRAL NERVOUS SYSTEM EFFECTS FROM THYROTROPIN-RELEASING ACTIVITY

Chemischer Informationsdienst ◽

10.1002/chin.198444319 ◽

1984 ◽

Vol 15 (44) ◽

Author(s):

T. SZIRTES ◽

L. KISFALUDY ◽

E. PALOSI ◽

L. SZPORNY

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

Hormone Analogs ◽

Complete Dissociation

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Synthesis and central nervous system actions of thyrotropin-releasing hormone analogs containing a 1-oxo-1,2,3,4-tetrahydroisoquinoline moiety.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.36.190 ◽

1988 ◽

Vol 36 (1) ◽

pp. 190-201 ◽

Author(s):

HIROSHI MAEDA ◽

MAMORU SUZUKI ◽

HIROSHI SUGANO ◽

MICHIO MAYAMURA ◽

RYUICHI ISHIDA

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

Hormone Analogs

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Synthesis and central nervous system actions of thyrotropin-releasing hormone analogs containing a 1-substituted 2-oxoimadazolidine moiety*

International journal of peptide & protein research ◽

10.1111/j.1399-3011.1989.tb00216.x ◽

2009 ◽

Vol 33 (6) ◽

pp. 403-411 ◽

Author(s):

HIROSHI MAEDA ◽

MAMORU SUZUKI ◽

HIROSHI SUGANO ◽

MICHIO YAMAMURA ◽

RYUICHI ISHIDA

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

Hormone Analogs

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Effect of Fasting on the Content of Thyrotropin-releasing Hormone and its mRNA in the Central Nervous System and Pyroglutamyl Peptidase II Activity in the Anterior Pituitary of Post-Weaned and Adult Rats

Nutritional Neuroscience ◽

10.1080/1028415x.2000.11747323 ◽

2000 ◽

Vol 3 (4) ◽

pp. 255-265 ◽

Author(s):

P. de Gortari ◽

M.E. González-Alzati ◽

M. Cisneros ◽

P. Joseph-Bravo

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Anterior Pituitary ◽

Thyrotropin Releasing Hormone ◽

Releasing Hormone ◽

The Central Nervous System

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Serotonin 5-HT7 receptor agents: Structure-activity relationships and potential therapeutic applications in central nervous system disorders

Pharmacology & Therapeutics ◽

10.1016/j.pharmthera.2010.08.013 ◽

2011 ◽

Vol 129 (2) ◽

pp. 120-148 ◽

Author(s):

Marcello Leopoldo ◽

Enza Lacivita ◽

Francesco Berardi ◽

Roberto Perrone ◽

Peter B. Hedlund

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Therapeutic Applications ◽

Structure Activity Relationships ◽

Central Nervous System Disorders ◽

Structure Activity

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