Small-Molecule Targeting of Heat Shock Protein 90 Chaperone Function:  Rational Identification of a New Anticancer Lead

2006 ◽  
Vol 49 (26) ◽  
pp. 7721-7730 ◽  
Author(s):  
Massimiliano Meli ◽  
Marzia Pennati ◽  
Maria Curto ◽  
Maria Grazia Daidone ◽  
Janet Plescia ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Small Molecule ◽  
Heat Shock Protein 90 ◽  
Chaperone Function

Application of Target-Mediated Drug Disposition Model to Small Molecule Heat Shock Protein 90 Inhibitors

2013 ◽  
Vol 41 (6) ◽  
pp. 1285-1294 ◽  
Author(s):  
Shinji Yamazaki ◽  
Zhongzhou Shen ◽  
Ying Jiang ◽  
Bill J. Smith ◽  
Paolo Vicini
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Small Molecule ◽  
Drug Disposition ◽  
Heat Shock Protein 90 ◽  
Target Mediated Drug Disposition ◽  
Disposition Model

scholarly journals Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90

2005 ◽  
Vol 280 (29) ◽  
pp. 26729-26734 ◽  
Author(s):  
Purva Bali ◽  
Michael Pranpat ◽  
James Bradner ◽  
Maria Balasis ◽  
Warren Fiskus ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Histone Deacetylase ◽  
Heat Shock Protein 90 ◽  
Histone Deacetylase 6 ◽  
Chaperone Function

scholarly journals Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects

2012 ◽  
Vol 109 (37) ◽  
pp. E2476-E2485 ◽  
Author(s):  
C. T. Chan ◽  
R. E. Reeves ◽  
R. Geller ◽  
S. S. Yaghoubi ◽  
A. Hoehne ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Small Molecule ◽  
Heat Shock Protein 90

scholarly journals Stimulation of heat shock protein 90 chaperone function through binding of a novobiocin analog KU-32

2019 ◽  
Vol 294 (16) ◽  
pp. 6450-6467 ◽  
Author(s):  
Bhaskar K. Chatterjee ◽  
Abhilash Jayaraj ◽  
Vinay Kumar ◽  
Brian Blagg ◽  
Rachel E. Davis ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 90 ◽  
Chaperone Function ◽  
Stimulation Of
Sign in / Sign up

Export Citation Format

Share Document