Structure-Based Design, Synthesis, and Structure−Activity Relationship Studies of HIV-1 Protease Inhibitors Incorporating Phenyloxazolidinones

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Hiv 1

Quantitative Structure-Activity Relationship of some HIV-1 Protease Inhibitors: A Fujita-Ban Type Analysis

Journal of Enzyme Inhibition ◽

10.1080/14756360109162368 ◽

2001 ◽

Vol 16 (3) ◽

pp. 185-197 ◽

Cited By ~ 1

Author(s):

S. B. Mekapati ◽

R. Sivakumar ◽

S. P. Gupta

Keyword(s):

Protease Inhibitors ◽

Activity Relationship ◽

Quantitative Structure ◽

Type Analysis ◽

Structure Activity ◽

Relationship Of ◽

Hiv 1

Structure–activity relationship of HIV-1 protease inhibitors containing α-hydroxy-β-amino acids. Detailed study of P 1 site

10.1016/s0968-0896(99)00127-3 ◽

1999 ◽

Vol 7 (9) ◽

pp. 2063-2072 ◽

Cited By ~ 15

Author(s):

Eiji Takashiro ◽

Ichiro Hayakawa ◽

Tamayo Nitta ◽

Atsushi Kasuya ◽

Shuichi Miyamoto ◽

...

Keyword(s):

Amino Acids ◽

Protease Inhibitors ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of ◽

Hiv 1

Improved Structure−Activity Relationship Analysis of HIV-1 Protease Inhibitors Using Interaction Kinetic Data

Journal of Medicinal Chemistry ◽

10.1021/jm0499110 ◽

2004 ◽

Vol 47 (24) ◽

pp. 5953-5961 ◽

Cited By ~ 34

Author(s):

Cynthia F. Shuman ◽

Lotta Vrang ◽

U. Helena Danielson

Keyword(s):

Protease Inhibitors ◽

Kinetic Data ◽

Activity Relationship ◽

Relationship Analysis ◽

Structure Activity ◽

Hiv 1

Improved P1/P1‘ Substituents for Cyclic Urea Based HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationship, and X-ray Crystal Structure Analysis

Journal of Medicinal Chemistry ◽

10.1021/jm960839i ◽

1997 ◽

Vol 40 (10) ◽

pp. 1465-1474 ◽

Cited By ~ 22

Author(s):

David A. Nugiel ◽

Kim Jacobs ◽

Lyndon Cornelius ◽

Chong-Hwan Chang ◽

Prabhakar K. Jadhav ◽

...

Keyword(s):

Crystal Structure ◽

Protease Inhibitors ◽

Structure Analysis ◽

Crystal Structure Analysis ◽

Activity Relationship ◽

X Ray ◽

Structure Activity ◽

Hiv 1

Structure–activity relationship of HIV-1 protease inhibitors containing AHPBA. Part III: modification of P2 site

10.1016/s0968-0896(98)00004-2 ◽

1998 ◽

Vol 6 (5) ◽

pp. 595-604 ◽

Cited By ~ 4

Author(s):

E Takashiro

Keyword(s):

Protease Inhibitors ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of ◽

Hiv 1

Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure–activity relationship study

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2013.05.005 ◽

2013 ◽

Vol 65 ◽

pp. 436-447 ◽

Cited By ~ 19

Author(s):

Pillaiyar Thanigaimalai ◽

Sho Konno ◽

Takehito Yamamoto ◽

Yuji Koiwai ◽

Akihiro Taguchi ◽

...

Keyword(s):

Protease Inhibitors ◽

Synthesis And Biological Evaluation

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study ◽

3Cl Protease ◽

Quantitative structure–activity relationship studies on cyclic cyanoguanidines acting as HIV-1 protease inhibitors

10.1016/s0968-0896(99)00175-3 ◽

1999 ◽

Vol 7 (11) ◽

pp. 2549-2553 ◽

Cited By ~ 10

Author(s):

S.P. Gupta ◽

M. Suresh Babu

Keyword(s):

Protease Inhibitors ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Hiv 1

A quantitative structure-activity relationship study for structurally diverse HIV-1 protease inhibitors: contribution of conformational flexibility to inhibitory activity

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756360600810233 ◽

2006 ◽

Vol 21 (5) ◽

pp. 609-615

Author(s):

Keigo Gohda

Keyword(s):

Protease Inhibitors ◽

Inhibitory Activity ◽

Conformational Flexibility ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Study ◽

Hiv 1

Exploring the structure–activity relationship of oxazolidinones as HIV-1 protease inhibitors—QSAR and pharmacophore modelling studies

Chemometrics and Intelligent Laboratory Systems ◽

10.1016/j.chemolab.2016.03.017 ◽

2016 ◽

Vol 154 ◽

pp. 52-61 ◽

Cited By ~ 4

Author(s):

Veerasamy Ravichandran ◽

Krishnamoorthy Venkateskumar ◽

Sivadasan Shalini ◽

Rajak Harish

Keyword(s):

Protease Inhibitors ◽

Activity Relationship ◽

Pharmacophore Modelling ◽

Structure Activity ◽

Modelling Studies ◽

Relationship Of ◽

Hiv 1

A quantitative structure–Activity relationship study on some sulfolanes and arylthiomethanes acting as HIV-1 protease inhibitors

10.1016/s0968-0896(98)00157-6 ◽

1998 ◽

Vol 6 (11) ◽

pp. 2185-2192 ◽

Cited By ~ 11

Author(s):

S.P. Gupta ◽

M.S. Babu ◽

S. Sowmya

Keyword(s):

Protease Inhibitors ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Study ◽

Hiv 1