Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 3. Structure–Activity Relationships within the Aryl Carbinol Region of the N-Arylsulfonamido-N′-arylpiperazine Series

2014 ◽  
Vol 57 (7) ◽  
pp. 3094-3116 ◽  
Author(s):  
Nobuko Nishimura ◽  
Mark H. Norman ◽  
Longbin Liu ◽  
Kevin C. Yang ◽  
Kate S. Ashton ◽  
...  
Keyword(s):  
Small Molecule ◽  
Protein Interaction ◽  
Regulatory Protein ◽  
Glucokinase Regulatory Protein ◽  
Structure Activity Relationships ◽  
Structure Activity

Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 4. Exploration of a Novel Binding Pocket

2014 ◽  
Vol 57 (14) ◽  
pp. 5949-5964 ◽  
Author(s):  
Fang-Tsao Hong ◽  
Mark H. Norman ◽  
Kate S. Ashton ◽  
Michael D. Bartberger ◽  
Jie Chen ◽  
...  
Keyword(s):  
Small Molecule ◽  
Protein Interaction ◽  
Regulatory Protein ◽  
Binding Pocket ◽  
Glucokinase Regulatory Protein
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