Exploitation of Cholane Scaffold for the Discovery of Potent and Selective Farnesoid X Receptor (FXR) and G-Protein Coupled Bile Acid Receptor 1 (GP-BAR1) Ligands

2014 ◽  
Vol 57 (20) ◽  
pp. 8477-8495 ◽  
Author(s):  
Carmen Festa ◽  
Barbara Renga ◽  
Claudio D’Amore ◽  
Valentina Sepe ◽  
Claudia Finamore ◽  
...  
Keyword(s):  
Bile Acid ◽  
G Protein ◽  
Farnesoid X Receptor ◽  
Acid Receptor ◽  
Bile Acid Receptor ◽  
G Protein Coupled

scholarly journals Farnesoid X receptor (FXR) and G protein-coupled bile acid receptor 1 (TGR5) signaling pathways improved the hepatic lipid metabolism in hybrid grouper

2022 ◽  
Vol 22 ◽  
pp. 100997
Author(s):  
Jia Xu ◽  
Guilun He ◽  
Liutong Chen ◽  
Shiwei Xie ◽  
Shuyan Chi ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Bile Acid ◽  
Signaling Pathways ◽  
G Protein ◽  
Farnesoid X Receptor ◽  
Hepatic Lipid Metabolism ◽  
Acid Receptor ◽  
Hybrid Grouper ◽  
Bile Acid Receptor ◽  
G Protein Coupled

Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity

Steroids ◽  
2016 ◽  
Vol 105 ◽  
pp. 59-67 ◽  
Author(s):  
Valentina Sepe ◽  
Barbara Renga ◽  
Carmen Festa ◽  
Claudia Finamore ◽  
Dario Masullo ◽  
...  
Keyword(s):  
Bile Acid ◽  
G Protein ◽  
Farnesoid X Receptor ◽  
Acid Receptor ◽  
Bile Acid Receptor ◽  
G Protein Coupled ◽  
Cholanoic Acid

Differential regulation of G-protein coupled bile acid receptor (Gpbar-1) by Sp1/KLF5 family transcription factors

2015 ◽  
Vol 53 (12) ◽  
Author(s):  
C Chintalapati ◽  
C Wöhler ◽  
C Ehlting ◽  
J Bode ◽  
D Häussinger ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Bile Acid ◽  
G Protein ◽  
Differential Regulation ◽  
Acid Receptor ◽  
Bile Acid Receptor ◽  
G Protein Coupled

scholarly journals The G protein coupled bile acid receptor TGR5 (Gpbar1) modulates endothelin-1 signaling in liver

2020 ◽  
Author(s):  
C Klindt ◽  
M Reich ◽  
B Hellweg ◽  
J Stindt ◽  
J Rahnenführer ◽  
...  
Keyword(s):  
Bile Acid ◽  
G Protein ◽  
Acid Receptor ◽  
Endothelin 1 ◽  
Bile Acid Receptor ◽  
G Protein Coupled

scholarly journals The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling Pathway

2015 ◽  
Vol 6 ◽  
Author(s):  
Cong Guo ◽  
Hui Qi ◽  
Yingjie Yu ◽  
Qiqi Zhang ◽  
Jia Su ◽  
...  
Keyword(s):  
Bile Acid ◽  
Signaling Pathway ◽  
G Protein ◽  
Acid Receptor ◽  
Bile Acid Receptor ◽  
G Protein Coupled

scholarly journals Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5

2017 ◽  
Vol 8 ◽  
Author(s):  
Angela Ladurner ◽  
Martin Zehl ◽  
Ulrike Grienke ◽  
Christoph Hofstadler ◽  
Nadina Faur ◽  
...  
Keyword(s):  
Bile Acid ◽  
G Protein ◽  
Acid Receptor ◽  
Triterpene Acids ◽  
Bile Acid Receptor ◽  
G Protein Coupled

Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5)

2018 ◽  
Vol 61 (17) ◽  
pp. 7589-7613 ◽  
Author(s):  
Tao Chen ◽  
Nicholas William Reich ◽  
Noah Bell ◽  
Patricia D. Finn ◽  
David Rodriguez ◽  
...  
Keyword(s):  
Bile Acid ◽  
G Protein ◽  
Acid Receptor ◽  
Bile Acid Receptor ◽  
G Protein Coupled
Sign in / Sign up

Export Citation Format

Share Document