Benzocyclobutadienyl Anion:  Formation and Energetics of an Antiaromatic Molecule

2000 ◽  
Vol 65 (20) ◽  
pp. 6566-6571 ◽  
Author(s):  
Katherine M. Broadus ◽  
Steven R. Kass
Keyword(s):  
Anion Formation ◽  
Antiaromatic Molecule

ChemInform Abstract: Benzocyclobutadienyl Anion: Formation and Energetics of an Antiaromatic Molecule.

ChemInform ◽  
2001 ◽  
Vol 32 (4) ◽  
pp. no-no
Author(s):  
Katherine M. Broadus ◽  
Steven R. Kass
Keyword(s):  
Anion Formation ◽  
Antiaromatic Molecule

scholarly journals Full-Colour Solvatochromic Fluorescence Emitted from a Semi-Aromatic Imide Compound Based on ESIPT and Anion Formation

2021 ◽  
Author(s):  
Tabuchi Atsuko ◽  
Teruaki Hayakawa ◽  
Shigeki Kuwata ◽  
Ryohei Ishige ◽  
Shinji Ando
Keyword(s):  
Visible Region ◽  
Anion Formation ◽  
Tosyl Group

A multi-colour solvatochromic fluorophore was developed by substituting a fully organic 3-amino-N-cyclohexyl phthalimide group with a p-toluenesulfonyl (tosyl) group. This compound is essentially colourless in the visible region and exhibits...

scholarly journals Antimicrobial, Antioxidant, and Cytotoxic Activities of Juglans regia L. Pellicle Extract

Antibiotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 159
Author(s):  
Floriana D’Angeli ◽  
Giuseppe Antonio Malfa ◽  
Adriana Garozzo ◽  
Giovanni Li Volti ◽  
Carlo Genovese ◽  
...  
Keyword(s):  
Herpes Simplex ◽  
Juglans Regia ◽  
Radical Scavenging ◽  
Fungal Growth ◽  
Bioactive Molecules ◽  
Total Phenolic ◽  
Cytotoxic Activities ◽  
Dependent Manner ◽  
Anion Formation ◽  
Herpes Simplex Viruses

The difficulty to treat resistant strains-related hospital-acquired infections (HAIs) promoted the study of phytoextracts, known sources of bioactive molecules. Accordingly, in the present study, the pharmacological activities of Juglans regia (L.) pellicle extract (WPE) were investigated. The antiviral effect was tested against Herpes simplex virus type 1 and 2, Poliovirus 1, Adenovirus 2, Echovirus 9, Coxsackievirus B1 through the plaque reduction assay. The antibacterial and antifungal activities were evaluated against medically important strains, by the microdilution method. DPPH and superoxide dismutase (SOD)s-like activity assays were used to determine the antioxidant effect. Besides, the extract was screened for cytotoxicity on Caco-2, MCF-7, and HFF1 cell lines by the 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay. The total phenolic and flavonoid contents were also evaluated. Interestingly, WPE inhibited Herpes simplex viruses (HSVs) replication, bacterial and fungal growth. WPE showed free radical scavenging capacity and inhibited superoxide anion formation in a dose-dependent manner. These effects could be attributed to the high content of phenols and flavonoids, which were 0.377 ± 0.01 mg GE/g and 0.292 ± 0.08 mg CE/g, respectively. Moreover, WPE was able to reduce Caco-2 cell viability, at both 48 h and 72 h. The promising results encourage further studies aimed to better elucidate the role of WPE in the prevention of human infectious diseases.

scholarly journals Subunit inequivalence in superoxide anion formation during photooxidation of human oxyhemoglobin.

1979 ◽  
Vol 254 (11) ◽  
pp. 4532-4535
Author(s):  
L.S. Demma ◽  
J.M. Salhany
Keyword(s):  
Superoxide Anion ◽  
Anion Formation

ChemInform Abstract: EPR AND RESONANCE RAMAN STUDIES OF THE (5,10,15,20-TETRAPHENYLPORPHINATO)FERRATE(I) ANION: FORMATION OF A FIVE-COORDINATE PYRIDINE ADDUCT

1985 ◽  
Vol 16 (43) ◽  
Author(s):  
G. S. SRIVATSA ◽  
D. T. SAWYER ◽  
N. J. BOLDT ◽  
D. F. BOCIAN
Keyword(s):  
Resonance Raman ◽  
Anion Formation

Further evidence of anion formation in rigid matrix photoionization and bleaching kinetics implications

1972 ◽  
Vol 16 (1) ◽  
pp. 68-71 ◽  
Author(s):  
J. Blais ◽  
M. Gauthier
Keyword(s):  
Anion Formation ◽  
Rigid Matrix

Strategic Approach for Enhancing Sensitivity of Ammonia Gas Detection: Molecular Design Rule and Morphology Optimization for Stable Radical Anion Formation of Rylene Diimide Semiconductors

2021 ◽  
pp. 2101981
Author(s):  
Byeong M. Oh ◽  
Sung‐Ha Park ◽  
Jeong Hyeon Lee ◽  
Jin Chul Kim ◽  
Jong Bum Lee ◽  
...  
Keyword(s):  
Radical Anion ◽  
Molecular Design ◽  
Stable Radical ◽  
Gas Detection ◽  
Design Rule ◽  
Ammonia Gas ◽  
Anion Formation ◽  
Strategic Approach

scholarly journals Alpha-Lipoic Acid Protects Cardiomyocytes against Heat Stroke-Induced Apoptosis and Inflammatory Responses Associated with the Induction of Hsp70 and Activation of Autophagy

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Hsin-Hsueh Shen ◽  
Yu-Shiuan Tseng ◽  
Ni-Chun Kuo ◽  
Ching-Wen Kung ◽  
Sherif Amin ◽  
...  
Keyword(s):  
Lipoic Acid ◽  
Myocardial Injury ◽  
Inflammatory Responses ◽  
Heat Stroke ◽  
Heat Exposure ◽  
Antioxidant Properties ◽  
Mitochondrial Enzymes ◽  
Protective Effects ◽  
Anion Formation ◽  
Anti Inflammatory

Heat stroke (HS) is a life-threatening illness and defined as when body temperature elevates above 40°C accompanied by the systemic inflammatory response syndrome that results in multiple organ dysfunctions. α-Lipoic acid (ALA) acts as a cofactor of mitochondrial enzymes and exerts anti-inflammatory and antioxidant properties in a variety of diseases. This study investigates the beneficial effects of ALA on myocardial injury and organ damage caused by experimental HS and further explores its underlying mechanism. Male Wistar rats were exposed to 42°C until their rectal core temperature reached 42.9°C and ALA was pretreared 40 or 80 mg/kg (i.v.) 1.5 h prior to heat exposure. Results showed that HS-induced lethality and hypothermia were significantly alleviated by ALA treatment that also improved plasma levels of CRE, LDH, and CPK and myocardial injury biomarkers myoglobin and troponin. In addition, ALA reduced cardiac superoxide anion formation and protein expression of cleaved caspase 3 caused by HS. Proinflammatory cytokine TNF-α and NF-κB pathways were significantly reduced by ALA treatment which may be associated with the upregulation of Hsp70. ALA significantly increased the Atg5-12 complex and LC3B II/LC3B I ratio, whereas the p62 and p-mTOR expression was attenuated in HS rats, indicating the activation of autophagy by ALA. In conclusion, ALA ameliorated the deleterious effects of HS by exerting antioxidative and anti-inflammatory capacities. Induction of Hsp70 and activation of autophagy contribute to the protective effects of ALA in HS-induced myocardial injury.

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