Molecular Recognition ofN-Acetylneuraminic Acid by Acyclic Pyridinium- and Quinolinium-Based Receptors in Aqueous Media: Recognition through Combination of Cationic and Neutral Recognition Sites

2012 ◽  
Vol 78 (2) ◽  
pp. 292-300 ◽  
Author(s):  
Christoph Geffert ◽  
Matthias Kuschel ◽  
Monika Mazik
Keyword(s):  
Molecular Recognition ◽  
Aqueous Media ◽  
Acetylneuraminic Acid ◽  
Recognition Sites

Visualization of molecular binding sites at the nanoscale in the lift-up mode by amplitude-modulation atomic force microscopy

Nanoscale ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 4213-4220
Author(s):  
Tatsuhiro Maekawa ◽  
Takashi Nyu ◽  
Evan Angelo Quimada Mondarte ◽  
Hiroyuki Tahara ◽  
Kasinan Suthiwanich ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Molecular Recognition ◽  
Amplitude Modulation ◽  
Binding Sites ◽  
Local Distribution ◽  
New Approach ◽  
Molecular Binding ◽  
Force Microscopy ◽  
Atomic Force ◽  
Recognition Sites

We report a new approach to visualize the local distribution of molecular recognition sites with nanoscale resolution by amplitude-modulation atomic force microscopy.

scholarly journals Molecular recognition sites on factor Xa which participate in the prothrombinase complex.

1992 ◽  
Vol 267 (17) ◽  
pp. 12323-12329
Author(s):  
A Chattopadhyay ◽  
H.L. James ◽  
D.S. Fair
Keyword(s):  
Molecular Recognition ◽  
Factor Xa ◽  
Prothrombinase Complex ◽  
Recognition Sites

scholarly journals Molecular recognition of surface-immobilized carbohydrates by a synthetic lectin

2014 ◽  
Vol 10 ◽  
pp. 1354-1364 ◽  
Author(s):  
Melanie Rauschenberg ◽  
Eva-Corrina Fritz ◽  
Christian Schulz ◽  
Tobias Kaufmann ◽  
Bart Jan Ravoo
Keyword(s):  
Molecular Recognition ◽  
Self Assembled Monolayers ◽  
Carbohydrate Binding ◽  
Air Oxidation ◽  
Acetylneuraminic Acid ◽  
Physiological Processes ◽  
Wide Range ◽  
Assembled Monolayers ◽  
Synthetic Carbohydrate ◽  
Derivatives Of

The molecular recognition of carbohydrates and proteins mediates a wide range of physiological processes and the development of synthetic carbohydrate receptors (“synthetic lectins”) constitutes a key advance in biomedical technology. In this article we report a synthetic lectin that selectively binds to carbohydrates immobilized in a molecular monolayer. Inspired by our previous work, we prepared a fluorescently labeled synthetic lectin consisting of a cyclic dimer of the tripeptide Cys-His-Cys, which forms spontaneously by air oxidation of the monomer. Amine-tethered derivatives of N-acetylneuraminic acid (NANA), β-D-galactose, β-D-glucose and α-D-mannose were microcontact printed on epoxide-terminated self-assembled monolayers. Successive prints resulted in simple microarrays of two carbohydrates. The selectivity of the synthetic lectin was investigated by incubation on the immobilized carbohydrates. Selective binding of the synthetic lectin to immobilized NANA and β-D-galactose was observed by fluorescence microscopy. The selectivity and affinity of the synthetic lectin was screened in competition experiments. In addition, the carbohydrate binding of the synthetic lectin was compared with the carbohydrate binding of the lectins concanavalin A and peanut agglutinin. It was found that the printed carbohydrates retain their characteristic selectivity towards the synthetic and natural lectins and that the recognition of synthetic and natural lectins is strictly orthogonal.

Imaging Chemical Groups and Molecular Recognition Sites on Live Cells Using AFM

2009 ◽  
pp. 33-48
Author(s):  
David Alsteens ◽  
Vincent Dupres ◽  
Etienne Dague ◽  
Claire Verbelen ◽  
Guillaume André ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Live Cells ◽  
Recognition Sites ◽  
Chemical Groups

Metal Ionochromic Effects of Conjugated Polymers:  Effects of the Rigidity of Molecular Recognition Sites on Metal Ion Sensing

2003 ◽  
Vol 107 (27) ◽  
pp. 6535-6538 ◽  
Author(s):  
Ming Zhang ◽  
Ping Lu ◽  
Yuguang Ma ◽  
Jiacong Shen
Keyword(s):  
Molecular Recognition ◽  
Conjugated Polymers ◽  
Metal Ion ◽  
Ion Sensing ◽  
Recognition Sites ◽  
Metal Ion Sensing

Temperature-Responsive Chromatography Using a Functional Polymer Modified Stationary Phase with Molecular Recognition Sites

2014 ◽  
Vol 71 (7) ◽  
pp. 293-301 ◽  
Author(s):  
Kazuki SAKATA ◽  
Kohei OHKUBO ◽  
Yuki HIRUTA ◽  
Eri AYANO ◽  
Hideko KANAZAWA
Keyword(s):  
Molecular Recognition ◽  
Stationary Phase ◽  
Functional Polymer ◽  
Temperature Responsive ◽  
Recognition Sites

Electrochemical and Raman characterization of molecular recognition sites in self-assembled monolayers

1988 ◽  
Vol 92 (20) ◽  
pp. 5575-5578 ◽  
Author(s):  
J. H. Kim ◽  
T. M. Cotton ◽  
R. A. Uphaus
Keyword(s):  
Molecular Recognition ◽  
Self Assembled Monolayers ◽  
Recognition Sites ◽  
Assembled Monolayers ◽  
Self Assembled ◽  
Raman Characterization

Probing molecular recognition sites on biosurfaces using AFM

Biomaterials ◽  
2007 ◽  
Vol 28 (15) ◽  
pp. 2393-2402 ◽  
Author(s):  
V DUPRES ◽  
C VERBELEN ◽  
Y DUFRENE
Keyword(s):  
Molecular Recognition ◽  
Recognition Sites
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