Development and Characterization of a Diamond-Based Localized Surface Plasmon Resonance Interface

2010 ◽  
Vol 114 (8) ◽  
pp. 3346-3353 ◽  
Author(s):  
Sabine Szunerits ◽  
Slimane Ghodbane ◽  
Joanna Niedziółka-Jönsson ◽  
Elisabeth Galopin ◽  
Frederik Klauser ◽  
...  
2008 ◽  
Vol 8 (7) ◽  
pp. 3369-3378 ◽  
Author(s):  
Xiaodong Zhou ◽  
Selven Virasawmy ◽  
Wolfgang Knoll ◽  
Kai Yu Liu ◽  
Man Siu Tse ◽  
...  

The gold nanostructures fabricated on a substrate yield localized surface plasmon resonance. We describe the fabrication and characterization of nanocrescents on a silicon substrate, which are fabricated by depositing a gold film at an oblique angle through nanosphere lithography. Following the etching of the gold perpendicular to the substrate and the removal of the nanospheres by dissolution, nanocrescents with fine nanostructures are generated. By varying the deposition angle of the gold film from 0° to 72°, nanorings, 2D and 3D nanocrescents can be obtained. During the nanocrescent fabrication, we also compared the deposition angle difference between the e-beam and thermal evaporators for oblique depositions of the gold. The 3D nanocrescents fabricated in our experiments are expected to have improved sensitivity in localized surface plasmon resonance measurements when compared to the previously reported 2D nanocrescents, which enable broader biosensor applications. Simulations of the profiles of these 3D nanocrescents using solid geometry show good consistency with the fabricated ones.


2021 ◽  
Vol 48 (3) ◽  
Author(s):  
Sina Vakili ◽  
◽  
Gholamreza Asadikaram ◽  
Masoud Torkzadeh-Mahani ◽  
Alimohammad Behroozikhah ◽  
...  

In this study, a localized surface plasmon resonance (LSPR) nanobiosensor was designed to quantify anti-Brucella antibodies in the human sera. Smooth Lipopolysaccharide (LPS) was extracted from Brucella melitensis via a modified hot phenol water method and fixed on the surface of the gold nanoparticles by covalent interactions with the functionalized nanoparticles. To obtain the best performance from the designed probe, the ratio of LPS to gold nanoparticle was optimized. Dynamic light scattering was used for the characterization of the probe. The reduction of the LSPR peak at 600nm was used to quantify the amount of captured anti-Brucella antibody. Finally, satisfactory results were obtained when the nanobiosensor was used to analyze the control and patient sera for the presence of anti-Brucella antibodies.


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