Specific Cation Effects on Hemoglobin Aggregation below and at Physiological Salt Concentration

Langmuir ◽  
2013 ◽  
Vol 29 (49) ◽  
pp. 15350-15358 ◽  
Author(s):  
Luca Medda ◽  
Cristina Carucci ◽  
Drew F. Parsons ◽  
Barry W. Ninham ◽  
Maura Monduzzi ◽  
...  
Keyword(s):  
Salt Concentration ◽  
Cation Effects ◽  
Physiological Salt Concentration

Salt Effects in Mucin Lubrication

1969 ◽  
Vol 91 (3) ◽  
pp. 371-373 ◽  
Author(s):  
C. W. McCutchen ◽  
J. F. Wilkins
Keyword(s):  
Salt Concentration ◽  
Entire Range ◽  
Good Evidence ◽  
Joint Fluid ◽  
Chain Polymer ◽  
Polymer Molecules ◽  
Lubricating Film ◽  
Joint Load ◽  
Long Chain ◽  
Physiological Salt Concentration

Animal joints are lubricated by two complementary mechanisms. Weeping lubrication carries most of the joint load hydrostatically, leaving only a small fraction of the total to be carried by rubbing of the solid “skeletons” of the two cartilages. This rubbing is, in turn, lubricated by the synovial mucin; i.e., by long chain polymer molecules dissolved in the joint fluid. There is good evidence that the mucin molecules adsorb to the surfaces and provide boundary lubrication. In this paper we examine further this adsorption processs using a bearing whose two surfaces are rubber and glass, respectively. It is found that the lubricating ability of the mucin is good if it is applied to the bearing in a solution with about physiological salt concentration. At higher salt concentrations the lubrication is comparatively poor, while at zero salt concentration it is very bad indeed. If, on the other hand, the mucin is applied at physiological salt concentration, and then the salt and unadsorbed mucin are washed away with distilled water the lubrication remains good, and has, on occasion, even improved. Once the mucin has been adsorbed the entire range of salt concentration can be explored, with the lubrication becoming worse at high salt concentration and then recovering in greater or lesser degree when the salt is washed off. It seems, then, that the salt concentration affects lubrication in two ways. It can upset the adsorption of the lubricating film, and it can change the lubricating effectiveness of the film once it is adsorbed.

Detection of Transplant Rejection Chemokine Protein Biomarker in Physiological Salt Concentration

2013 ◽  
Vol 13 (2) ◽  
pp. 438-439 ◽  
Author(s):  
F. S. Tulip ◽  
E. Eteshola ◽  
S. Desai ◽  
S. Mostafa ◽  
S. Roopa ◽  
...  
Keyword(s):  
Salt Concentration ◽  
Transplant Rejection ◽  
Protein Biomarker ◽  
Physiological Salt Concentration

scholarly journals Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

2011 ◽  
Vol 108 (20) ◽  
pp. 8251-8256 ◽  
Author(s):  
E. Arbely ◽  
E. Natan ◽  
T. Brandt ◽  
M. D. Allen ◽  
D. B. Veprintsev ◽  
...  
Keyword(s):  
Dna Binding ◽  
Salt Concentration ◽  
Binding Specificity ◽  
Dna Binding Specificity ◽  
Physiological Salt Concentration

scholarly journals Polypeptide-participating complex nanoparticles with improved salt-tolerance as excellent candidates for intelligent insulin delivery

RSC Advances ◽  
2017 ◽  
Vol 7 (23) ◽  
pp. 14088-14098 ◽  
Author(s):  
Yuqiang Li ◽  
Yunyan Zhang ◽  
Junjiao Yang ◽  
Jing Yang
Keyword(s):  
Salt Tolerance ◽  
Salt Concentration ◽  
Insulin Delivery ◽  
Ordered Structures ◽  
Responsive Materials ◽  
Synthetic Polypeptides ◽  
Physiological Salt Concentration

The strategy of introducing synthetic polypeptides with hierarchical ordered structures into glucose-responsive materials is reported in this study to achieve self-regulated release of insulin under physiological salt concentration.

Electrooptical analysis of α-chymotrypsin at physiological salt concentration

1996 ◽  
Vol 58 (1-2) ◽  
pp. 21-28 ◽  
Author(s):  
Thomas Schönknecht ◽  
Dietmar Pörschke
Keyword(s):  
Salt Concentration ◽  
Physiological Salt Concentration

scholarly journals Preparation of Asymmetric Vesicles with Trapped CsCl Avoids Osmotic Imbalance, Non-Physiological External Solutions, and Minimizes Leakage

2021 ◽  
Author(s):  
Ming-Hao Li ◽  
Daniel P. Raleigh ◽  
Erwin London
Keyword(s):  
Osmotic Pressure ◽  
Salt Concentration ◽  
Sucrose Gradient ◽  
Gradient Centrifugation ◽  
Salt Solutions ◽  
High Concentration ◽  
Multilamellar Vesicles ◽  
Sucrose Gradient Centrifugation ◽  
Subsequent Separation ◽  
Physiological Salt Concentration

The natural asymmetry of cellular membranes influences their properties. In recent years, methodologies for preparing asymmetric vesicles have been developed that rely on the methyl-α-cyclodextrin catalyzed exchange of lipids between donor lipid multilamellar vesicles and acceptor lipid unilamellar vesicles, and the subsequent separation of the, now asymmetric, acceptor vesicles from the donors. Isolation is accomplished by pre-loading acceptor vesicles with a high concentration of sucrose, typically 25% (w/w), and separating from donor and cyclodextrin by sucrose gradient centrifugation. We found that when the asymmetric vesicles were dispersed under hypotonic conditions using physiological salt solutions, there was enhanced leakage of an entrapped probe, 6-carboxyfluorescein. Studies with symmetric vesicles showed this was due to osmotic pressure and was specific to hypotonic solutions. Inclusion of cholesterol partly reduced leakage but did not completely eliminate it. To avoid having to use hypotonic conditions or to suspend vesicles at non-physiological solute concentrations to minimize leakage, a method for preparing asymmetric vesicles using acceptor vesicle-entrapped CsCl at a physiological salt concentration (100 mM) was developed. Asymmetric vesicles prepared with the entrapped CsCl protocol were highly resistant to 6-carboxyfluorescein.

Self-diffusion study of bile salt-monoolein micelles determination of the intermicellar bile salt concentration

1983 ◽  
Vol 80 ◽  
pp. 315-323 ◽  
Author(s):  
Marc Lindheimer ◽  
Jean-Claude Montet ◽  
Roselyne Bontemps ◽  
Jacques Rouviere ◽  
Bernard Brun
Keyword(s):  
Bile Salt ◽  
Salt Concentration ◽  
Diffusion Study ◽  
Bile Salt Concentration ◽  
Self Diffusion

Effect of High Salt Concentration on Ion Clustering and Transport in Polymer Solid Electrolytes: a Molecular Dynamics Study of PEO-LiTFSI

2018 ◽  
Author(s):  
Nicola Molinari ◽  
Jonathan P. Mailoa ◽  
Boris Kozinsky
Keyword(s):  
Polymer Electrolyte ◽  
Salt Concentration ◽  
Rational Design ◽  
Material System ◽  
Ion Dynamics ◽  
High Concentration ◽  
Anion Clusters ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

<div> <div> <div> <p>The model and analysis methods developed in this work are generally applicable to any polymer electrolyte/cation-anion combination, but we focus on the currently most prominent polymer electrolyte material system: poly(ethylene) oxide/Li- bis(trifluoromethane) sulfonamide (PEO + LiTFSI). The obtained results are surprising and challenge the conventional understanding of ionic transport in polymer electrolytes: the investigation of a technologically relevant salt concentration range (1 - 4 M) revealed the central role of the anion in coordinating and hindering Li ion movement. Our results provide insights into correlated ion dynamics, at the same time enabling rational design of better PEO-based electrolytes. In particular, we report the following novel observations. 1. Strong binding of the Li cation with the polymer competes with significant correlation of the cation with the salt anion. 2. The appearance of cation-anion clusters, especially at high concentration. 3. The asymmetry in the composition (and therefore charge) of such clusters; specifically, we find the tendency for clusters to have a higher number of anions than cations.</p> </div> </div> </div>

Sign in / Sign up

Export Citation Format

Share Document