Preparation and Characterization of Inclusion Complexes between Methylated Cyclodextrins and Poly(tetrahydrofuran)

1999 ◽  
Vol 32 (21) ◽  
pp. 7202-7207 ◽  
Author(s):  
Miyuko Okada ◽  
Mikiharu Kamachi ◽  
Akira Harada
Author(s):  
D. Nagasamy Venkatesh ◽  
S. Karthick ◽  
M. Umesh ◽  
G. Vivek ◽  
R.M. Valliappan ◽  
...  

Roxythromycin/ β-cyclodextrin (Roxy/ β-CD) dispersions were prepared with a view to study the influence of β-CD on the solubility and dissolution rate of this poorly soluble drug. Phase-solubility profile indicated that the solubility of roxythromycin was significantly increased in the presence of β-cyclodextrin and was classified as AL-type, indicating the 1:1 stoichiometric inclusion complexes. Physical characterization of the prepared systems was carried out by differential scanning calorimetry (DSC), X-ray diffraction studies (XRD) and IR studies. Solid state characterization of the drug β-CD binary system using XRD, FTIR and DSC revealed distinct loss of drug crystallinity in the formulation, ostensibly accounting for enhancement of dissolution rate.


Author(s):  
Alexander Puentes Parra ◽  
Jorge Ariel Martínez Ramírez ◽  
Claudia Elizabeth Mora Huertas

Polymer ◽  
2001 ◽  
Vol 42 (16) ◽  
pp. 6907-6912 ◽  
Author(s):  
Francis E Porbeni ◽  
Efe M Edeki ◽  
I Dan Shin ◽  
Alan E Tonelli
Keyword(s):  

2010 ◽  
Vol 53 (11) ◽  
pp. 2304-2310 ◽  
Author(s):  
Nan Dong ◽  
MeiYu Dong ◽  
AnTing Zhao ◽  
QianJiang Zhu ◽  
Zhu Tao ◽  
...  
Keyword(s):  

2020 ◽  
Vol 17 (11) ◽  
pp. 4241-4255
Author(s):  
Konstantina Manta ◽  
Paraskevi Papakyriakopoulou ◽  
Maria Chountoulesi ◽  
Dimitrios A. Diamantis ◽  
Dimitrios Spaneas ◽  
...  

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