scholarly journals Efficient Intracellular Delivery of Molecules with High Cell Viability Using Nanosecond-Pulsed Laser-Activated Carbon Nanoparticles

ACS Nano ◽  
2014 ◽  
Vol 8 (3) ◽  
pp. 2889-2899 ◽  
Author(s):  
Aritra Sengupta ◽  
Sean C. Kelly ◽  
Nishant Dwivedi ◽  
Naresh Thadhani ◽  
Mark R. Prausnitz
Keyword(s):  
Activated Carbon ◽  
Cell Viability ◽  
Carbon Nanoparticles ◽  
Pulsed Laser ◽  
Intracellular Delivery ◽  
High Cell ◽  
Nanosecond Pulsed Laser

Near-infrared nanosecond-pulsed laser-activated highly efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles

Nanoscale ◽  
2020 ◽  
Vol 12 (22) ◽  
pp. 12057-12067 ◽  
Author(s):  
Tuhin Subhra Santra ◽  
Srabani Kar ◽  
Te-Chang Chen ◽  
Chih-Wei Chen ◽  
Jayant Borana ◽  
...  
Keyword(s):  
Cell Viability ◽  
Near Infrared ◽  
Pulsed Laser ◽  
Intracellular Delivery ◽  
High Cell ◽  
Polystyrene Nanoparticles ◽  
Infrared Wavelength ◽  
Highly Efficient ◽  
Nanosecond Pulsed Laser

Here, an efficient intracellular delivery of molecules with high cell viability is reported using plasmonic photoporation mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles at near-infrared wavelength.

Synthesis of water-soluble fluorescent carbon nanoparticles (CNPs) from nanosecond pulsed laser ablation in ethanol

2021 ◽  
Vol 135 ◽  
pp. 106717
Author(s):  
Gaurav Kumar Yogesh ◽  
E.P. Shuaib ◽  
A. Kalai Priya ◽  
P. Rohini ◽  
Sathyan Vivekanand Anandhan ◽  
...  
Keyword(s):  
Laser Ablation ◽  
Carbon Nanoparticles ◽  
Pulsed Laser ◽  
Pulsed Laser Ablation ◽  
Water Soluble ◽  
Nanosecond Pulsed Laser ◽  
Fluorescent Carbon Nanoparticles ◽  
Fluorescent Carbon

Nano-localized single-cell nano-electroporation

Lab on a Chip ◽  
2020 ◽  
Vol 20 (22) ◽  
pp. 4194-4204
Author(s):  
Tuhin Subhra Santra ◽  
Srabani Kar ◽  
Hwan-You Chang ◽  
Fan-Gang Tseng
Keyword(s):  
Cell Viability ◽  
Single Cell ◽  
Intracellular Delivery ◽  
High Cell ◽  
Highly Efficient

We demonstrated nano-electroporation technique to create transient nano-holes at single or multiple nano-localized positions of a single-cell for a highly efficient intracellular delivery with high cell viability.

Parameters affecting intracellular delivery of molecules using laser-activated carbon nanoparticles

2016 ◽  
Vol 12 (4) ◽  
pp. 1003-1011 ◽  
Author(s):  
Prerona Chakravarty ◽  
Christopher D. Lane ◽  
Thomas M. Orlando ◽  
Mark R. Prausnitz
Keyword(s):  
Activated Carbon ◽  
Carbon Nanoparticles ◽  
Intracellular Delivery

Inside process of glass with nanosecond pulsed laser

2008 ◽  
Author(s):  
Takeji Arai ◽  
Noritaka Asano ◽  
Akihiko Minami ◽  
Hideaki Kusano
Keyword(s):  
Pulsed Laser ◽  
Nanosecond Pulsed Laser

Probing Cellular Outcomes Using Heterobivalent Constructs

2019 ◽  
Author(s):  
Rohit Bhadoria ◽  
Kefeng Ping ◽  
Christer Lohk ◽  
Ivar Järving ◽  
Pavel Starkov
Keyword(s):  
Cell Viability ◽  
Small Molecules ◽  
Cellular Uptake ◽  
Kinase Inhibitors ◽  
Rho Kinase ◽  
Intracellular Delivery ◽  
Rho Kinase Inhibitors

<div> <div> <div> <p>Conjugation techniques are central to improving intracellular delivery of bioactive small molecules. However, tracking and assessing the overall biological outcome of these constructs remains poorly understood. We addressed this issue by having developed a focused library of heterobivalent constructs based on Rho kinase inhibitors to probe various scenarios. By comparing induction of a phenotype of interest vs. cell viability vs. cellular uptake, we demonstrate that such conjugates indeed lead to divergent cellular outcomes. </p> </div> </div> </div>

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