Role of MAP kinase in the enhanced cell proliferation of long term estrogen deprived human breast cancer cells

2000 ◽  
Vol 62 (3) ◽  
pp. 167-175 ◽  
Author(s):  
Meei-Huey Jeng ◽  
Wei Yue ◽  
Anne Eischeid ◽  
Ji-Ping Wang ◽  
Richard J. Santen
Keyword(s):  
Breast Cancer ◽  
Cell Proliferation ◽  
Map Kinase ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast

Role of polyamines in the growth of hormone-responsive and - resistant human breast cancer cells in nude mice

1992 ◽  
Vol 66 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Andrea Manni ◽  
Betty Badger ◽  
Juliann Martel ◽  
Laurence Demers
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Nude Mice ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast

scholarly journals Mango Fruit Extracts Differentially Affect Proliferation and Intracellular Calcium Signalling in MCF-7 Human Breast Cancer Cells

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Meng-Wong Taing ◽  
Jean-Thomas Pierson ◽  
Paul N. Shaw ◽  
Ralf G. Dietzgen ◽  
Sarah J. Roberts-Thomson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Proliferation ◽  
Intracellular Calcium ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Cultivar Differences ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Mcf 7

The assessment of human cancer cell proliferation is a common approach in identifying plant extracts that have potential bioactive effects. In this study, we tested the hypothesis that methanolic extracts of peel and flesh from three archetypal mango cultivars, Irwin (IW), Nam Doc Mai (NDM), and Kensington Pride (KP), differentially affect proliferation, extracellular signal-regulated kinase (ERK) activity, and intracellular calcium ([Ca2+]I) signalling in MCF-7 human breast cancer cells. Mango flesh extracts from all three cultivars did not inhibit cell growth, and of the peel extracts only NDM reduced MCF-7 cell proliferation. Mango cultivar peel and flesh extracts did not significantly change ERK phosphorylation compared to controls; however, some reduced relative maximal peak[Ca2+]Iafter adenosine triphosphate stimulation, with NDM peel extract having the greatest effect among the treatments. Our results identify mango interfruit and intrafruit (peel and flesh) extract variability in antiproliferative effects and[Ca2+]Isignalling in MCF-7 breast cancer cells and highlight that parts of the fruit (such as peel and flesh) and cultivar differences are important factors to consider when assessing potential chemopreventive bioactive compounds in plants extracts.

Role of Prolactin Receptor in Growth Hormone Signaling in Human Breast Cancer Cells.

2010 ◽  
pp. OR33-6-OR33-6
Author(s):  
Jie Xu ◽  
Jing Jiang ◽  
Peter E Lobie ◽  
Serge Y Fuchs ◽  
Stuart J Frank
Keyword(s):  
Breast Cancer ◽  
Growth Hormone ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Prolactin Receptor ◽  
Hormone Signaling ◽  
Human Breast Cancer Cells ◽  
Human Breast

Calcitriol inhibits Ether-à go-go potassium channel expression and cell proliferation in human breast cancer cells

2010 ◽  
Vol 316 (3) ◽  
pp. 433-442 ◽  
Author(s):  
Rocío García-Becerra ◽  
Lorenza Díaz ◽  
Javier Camacho ◽  
David Barrera ◽  
David Ordaz-Rosado ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Proliferation ◽  
Potassium Channel ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Channel Expression
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