Fever of unknown origin: Importance of 18F-FDG PET/CT in the diagnosis of a late infectious complication after aneurysm bypass

VASA ◽  
2011 ◽  
Vol 40 (5) ◽  
pp. 418-421 ◽  
Author(s):  
Goudard ◽  
Pierret ◽  
Dusaud ◽  
Falzone ◽  
Tourtier ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Secondary Infection ◽  
False Negative ◽  
Artery Aneurysm ◽  
Low Grade ◽  
Popliteal Artery Aneurysm ◽  
Popliteal Aneurysm ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Persistent blood flow in aneurysmal sac after bypass-exclusion is well documented in the literature. Aneurysm enlargement, local compressive symptoms and even sac rupture are commonly described complications. Late secondary infection of popliteal artery aneurysm (PAA) following ligation and venous bypass is exceptional. We report the case of late PAA infection six years after bypass-exclusion in a 75 year-old man which was diagnosed by 18F-FDG PET/CT. The patient was successfully treated by aneurysm resection and antibiotics. The diagnosis of popliteal aneurysm infection is often clinical, echographic and sonographic, but computed tomography scan can be false negative in chronic low-grade infection. 18F-FDG PET/CT is able to accurately diagnose and localize infection with high sensibility and specificity.

scholarly journals The role of 18F-FDG PET/CT in the management of large-vessel vasculitis: applications and limitations in clinical practice

2012 ◽  
pp. 249-254
Author(s):  
Maria V. Mattoli ◽  
Giorgio Treglia ◽  
Lucia Leccisotti ◽  
Alessandro Giordano
Keyword(s):  
Clinical Practice ◽  
Fdg Pet ◽  
False Negative ◽  
Large Vessel Vasculitis ◽  
Large Vessel ◽  
Metabolic Imaging ◽  
Small Vessel Vasculitis ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Introduction: 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) plays a key role in oncology, and it is now being used increasingly to diagnose, characterize, and monitor disease activity in inflammatory disorders, including vasculitis. Unfortunately, its role in the management of vasculitis is still not well-defined, and clinicians are often unsure how this metabolic imaging technique should be used in these diseases, although its usefulness in diagnosing large-vessel vasculitis has been clearly demonstrated. Materials and methods: We reviewed the literature about the use of PET/CT in the management of vasculitis in an attempt to identify the applications and the limitations of this technique in clinical practice. Results and discussion: Our literature review revealed that 18F-FDG PET/CT is a useful tool for diagnosing vasculitis (especially when the symptoms of the disease are non-specific); guiding biopsy procedures (areas with high glucose consumption); evaluating disease extension; and monitoring treatment responses. The main limitations of this method are the relatively low spatial resolution of the tomograph, which can lead to false-negative results in the presence of small-vessel vasculitis, and risk of false positive results, especially those related to the presence of atherosclerosis and to post-treatment vascular remodeling.

Diagnosis of infective endocarditis by 18F-FDG-PET/CT, presentation of a false negative result

2018 ◽  
Vol 150 (6) ◽  
pp. 247-248
Author(s):  
Beatriz Colina Andrés ◽  
Maite Arbulu Tapia ◽  
Miguel Ángel Goenaga Sánchez
Keyword(s):  
Infective Endocarditis ◽  
Fdg Pet ◽  
False Negative ◽  
False Negative Result ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Detection of complete response to imatinib mesylate (Glivec®/Gleevec®) with 18F-FDG PET/CT for low-grade endometrial stromal sarcoma

2008 ◽  
Vol 63 (3) ◽  
pp. 555-559 ◽  
Author(s):  
Mehmet Emin Kalender ◽  
Alper Sevinc ◽  
Mustafa Yilmaz ◽  
Coskun Ozsarac ◽  
Celalettin Camci
Keyword(s):  
Imatinib Mesylate ◽  
Fdg Pet ◽  
Endometrial Stromal Sarcoma ◽  
Complete Response ◽  
Low Grade ◽  
Stromal Sarcoma ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Common hepatic artery aneurysm detected by 18F-FDG PET/CT Imaging

2021 ◽  
Vol 16 (11) ◽  
pp. 3157-3161
Author(s):  
Janata F ◽  
Fezoulidis N ◽  
Barachini O ◽  
Mirzaei S ◽  
Hergan K ◽  
...  
Keyword(s):  
Hepatic Artery ◽  
Fdg Pet ◽  
Artery Aneurysm ◽  
Ct Imaging ◽  
Common Hepatic Artery ◽  
Hepatic Artery Aneurysm ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

False negative scintigraphy with 99mTc-sestamibi in parathyroid carcinoma with associated brown tumors. Contributions of 18F-FDG-PET/CT

2011 ◽  
Vol 30 (3) ◽  
pp. 174-179
Author(s):  
A. Santiago Chinchilla ◽  
C. Ramos Font ◽  
M.A. Muros de Fuentes ◽  
M. Navarro-Pelayo Láinez ◽  
H. Palacios Gerona ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Parathyroid Carcinoma ◽  
False Negative ◽  
Pet Ct ◽  
Brown Tumors ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
99Mtc Sestamibi

scholarly journals 18F-FDG-PET/CT Evaluation of Indeterminate Adrenal Masses in Noncancer Patients

2021 ◽  
Author(s):  
Xin He ◽  
Elaine M Caoili ◽  
Anca M Avram ◽  
Barbra S Miller ◽  
Tobias Else
Keyword(s):  
Fdg Pet ◽  
False Negative ◽  
Blood Pool ◽  
Adrenal Tumors ◽  
Negative Results ◽  
False Negative Results ◽  
Pet Ct ◽  
Adrenal Masses ◽  
18F Fdg ◽  
Fdg Pet Ct

Abstract Context Adrenal tumors in noncancer patients are common. Objective Evaluate performance of 18F-fluorodeoxyglucose positron emission tomography computed tomography (18F-FDG-PET/CT) in distinguishing between benign and malignant adrenal tumors. Design Retrospective chart review 2010-2019. Setting Academic institution. Patients One hundred and seventeen noncancer patients, defined as having no history of cancer or with cancer in remission for ≥5 years, completed 18F-FDG-PET/CT to evaluate adrenal masses, with pathologic diagnoses or imaging follow-up (≥12 months). Intervention 18F-FDG-PET/CT of 117 indeterminate adrenal masses. Main Outcome Measures Receiver operator characteristic curve of the ratios of adrenal lesion standardized uptake value (SUV)max to liver SUVmean and of adrenal lesion SUVmax to aortic arch blood pool SUVmean were constructed. Results Seventy benign and 47 malignant masses (35 adrenocortical carcinomas [ACCs], 12 adrenal metastases) were identified. Malignant masses had higher median liver SUV and blood pool SUV ratios than benign masses (6.2 and 7.4 vs 1.4 and 2.0, P < .001). Median liver and blood pool SUV ratios of ACC (6.1 and 7.3, respectively) and metastases (6.7 and 7.7, respectively) were higher than those of than adenomas (1.4 and 2.2, P < .05 for all comparisons). Optimal liver SUV ratio to discern between benign and malignant masses was 2.5, yielding 85% sensitivity, 90% specificity, and 7 false negative results (including 3 ACCs). Optimal blood pool SUV ratio was 3.4, yielding 83% sensitivity, 90% specificity, and 8 false negative results (including 4 ACCs). Conclusion When used in conjunction with other clinical assessments, 18F-FDG-PET/CT can be a valuable tool in evaluating adrenal masses in noncancer patients.

Incidental 18F-FDG PET/CT finding of COVID-1 pneumonia in asymptomatic patient diagnosed with lung abscess metastasis

2020 ◽  
Author(s):  
Antoni Mestre-Fusco ◽  
Mònica Velasco-Nuño ◽  
Montserrat Negre-Busó ◽  
Núria Ferran ◽  
Sergi Juanpere ◽  
...  
Keyword(s):  
Ct Scan ◽  
Fdg Pet ◽  
Lung Abscess ◽  
Low Grade ◽  
Rt Pcr ◽  
Severe Respiratory Distress ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Pet Ct Scan

Abstract A 66-year-old male patient, with chronic respiratory disease and right colon resection in March 2017 for colon low-grade adenocarcinoma was assessed for recurrence suggested by elevated levels of tumor marker and no evidence of oncological disease by CT scan. 18F-FDG PET/CT showed bilateral multiple peripheral FDG-avid foci that matched with a peripheral predominant ground-glass opacities (GGOs) observed in lower lobes and multiple FDG-positive enlarged lymph nodes were also identified in the mediastinum. Patient was hospitalized in March 14th 2020, one day after PET/CT scan, with cough, wheezing and fever, and was treated with anti-inflammatory drugs. A first SARS-CoV-2 RT-PCR in March 15th resulted as negative and patient was treated with antibiotic therapy lead to an improvement of respiratory symptoms. PET/CT scan was interpreted as a pneumonia foci. A deteriorating patient condition was observed, with respiratory symptomatology progression, fatigue and D-Dimer elevation and a new RT-PCR resulted positive. A week after PET/CT scan, hospitalization in intensive care unit was necessary for rapidly disease progression and severe respiratory distress syndrome and patient died four days later.

scholarly journals Glucose Loading Enhances the Value of 18F-FDG PET/CT for the Characterization and Delineation of Cerebral Gliomas

Cancers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1977
Author(s):  
Dongwoo Kim ◽  
Hae Young Ko ◽  
Sangwon Lee ◽  
Yong-ho Lee ◽  
Sujin Ryu ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Characteristic Curve ◽  
Low Grade ◽  
High Grade ◽  
Glucose Loading ◽  
Pet Ct ◽  
Significant Difference ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Normal Cortex

This study aimed to assess how to enhance the value of 18F-Fluorodeoxyglucose (FDG) PET/CTs for glioma grading and better delineation of the tumor boundary by glucose loading. In mouse models of brain tumor using U87MG cells, 18F-FDG-PET images were obtained after fasting and after glucose loading. There was a significant difference in the tumor-to-normal cortex-uptake ratio (TNR) between the fasting and glucose-loading scans. 14C-2-Deoxy-D-glucose (14C-DG) uptake was measured in vitro using U87MG, U373MG and primary neurons cultured with different concentrations of glucose. The tumor-to-neuron ratio of 14C-DG uptake increased with up to 10 mM of glucose. Finally, 10 low-grade and 17 high-grade glioma patients underwent fasting and glucose loading 18F-FDG PET/CT and the TNR was compared between scans. The effect of glucose loading was significant in high-grade but not in low-grade gliomas. The receiver operating characteristic curve analyses with a cut-off TNR of 0.81 showed a higher area under the curve after glucose loading than fasting for differentiating low-grade versus high-grade gliomas. In addition, the glucose loading PET/CT was more useful than the fasting PET/CT for the discrimination of oligodendrogliomas from IDH-wildtype glioblastomas. Glucose loading resulted in a greater reduction in 18F-FDG uptake in the normal cortex than in tumors, which increases the usefulness of 18F-FDG PET/CT for grading.

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