Confirmatory factor analysis of the Mattis Dementia Rating Scale in patients with Alzheimer's disease.

ABSTRACTBackground: The aim of this study was to investigate the clustering of symptoms on the Neuropsychiatric Inventory (NPI) and the relative prevalence of symptom clusters in mild and moderate Alzheimer's disease (AD).Methods: Confirmatory factor analysis (CFA) was performed on the polychoric correlation matrix of 12 NPI items (scored yes or no) using the weighted least squares with mean and variance adjustment (WLSMV) estimator in Mplus (N = 224 community-dwelling Chinese persons with mild/moderate AD). Severity of AD was determined by Clinical Dementia Rating scores. The relative model fit of three competing measurement models (also known as factor structures) was tested using a modified χ2 difference test. Prevalence rates across mild and moderate stages were compared using χ2 tests. Furthermore, the measurement model of choice was cross-validated in an independent sample of 181 community-dwelling persons with dementia.Results: CFA supported a four-factor model, namely behavioral problems (agitation/aggressiveness, disinhibition, irritability, and aberrant motor behavior), psychosis (delusions and hallucinations), mood disturbance (depression, anxiety, sleep, appetite, and apathy), and euphoria (a stand-alone item that is equivalent to the factor). The most prevalent symptom clusters were behavioral (72%) and mood (69%) disturbances, followed by psychosis (45%). Euphoria was rare (6%). All syndromes were more prevalent in moderate than in mild stage, except for euphoria. In addition, the four-factor model was replicated in the cross-validation sample.Conclusions: The four syndromes provide a parsimonious conceptualization of neuropsychiatric symptoms corresponding to clinical observations and neurochemical changes of the disease. The independent replication in the second sample supports generalization of the four-factor model in Chinese persons with AD.

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The NINCDS-ADRDA neuropsychological criteria for Alzheimer's disease: a confirmatory factor analysis of single versus multi-factor models

Archives of Clinical Neuropsychology ◽

10.1016/s0887-6177(00)80181-x ◽

2000 ◽

Vol 15 (8) ◽

pp. 747

Author(s):

D Loewenstein

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Factor Analysis ◽

Confirmatory Factor Analysis ◽

Factor Models ◽

Confirmatory Factor ◽

Single Versus

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Spanish version of the Mattis Dementia Rating Scale-2 for early detection of Alzheimer's disease and mild cognitive impairment

International Journal of Geriatric Psychiatry ◽

10.1002/gps.4707 ◽

2017 ◽

Vol 33 (6) ◽

pp. 832-840 ◽

Cited By ~ 1

Author(s):

Elina Boycheva ◽

Israel Contador ◽

Bernardino Fernández-Calvo ◽

Francisco Ramos-Campos ◽

Verónica Puertas-Martín ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Early Detection ◽

Rating Scale ◽

Spanish Version ◽

Mattis Dementia Rating Scale ◽

Dementia Rating Scale

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Performance of Mattis dementia rating scale-Chinese Version in patients with mild cognitive impairment and Alzheimer's disease

10.21203/rs.3.rs-16409/v5 ◽

2020 ◽

Author(s):

Shuxia Qian ◽

Keliang Chen ◽

Qiaobing Guan ◽

Qihao Guo

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Sensitivity And Specificity ◽

Roc Curve ◽

Rating Scale ◽

Chinese Version ◽

Roc Curve Analysis ◽

Mattis Dementia Rating Scale ◽

Sensitive Function ◽

Dementia Rating Scale

Abstract Background: To identify the applicability of the Chinese Version of Mattis Dementia Rating Scale (DRS-CV).Methods: The DRS-CV was administered to 483 participants, including 136 normal controls, 167 patients with mild cognition impairment (MCI), and 180 patients with Alzheimer’s disease (AD). Receiver Operating Characteristic (ROC) curve was used to evaluate the sensitivity and specificity of the scale.Results: The scores of DRS-CV were ranked in the order of NC >MCI > mild AD > moderate AD group. Memory was the sensitive function affected at a relatively earlier stage of AD. ROC curve analysis indicated the DRS-CV total score and memory subscale showed excellent sensitivity and specificity in the discrimination between MCI from mild AD and mild AD from moderate AD, but poor sensitivity and specificity in the discrimination between MCI and NC.Conclusion: The DRS-CV is useful to the early diagnosis and severity of AD, not to the early identification of MCI.

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Familism Scale: Confirmatory Factor Analysis in a Sample of Caregivers of Older Adults

Paidéia (Ribeirão Preto) ◽

10.1590/1982-4327e2936 ◽

2019 ◽

Vol 29 ◽

Author(s):

Deusivania Vieira da Silva Falcão ◽

Daniel Paulson ◽

Manuel Herrera Legon ◽

Carolina Irurita-Ballesteros

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Factor Analysis ◽

Confirmatory Factor Analysis ◽

Factor Structure ◽

Depression Scale ◽

Epidemiological Studies ◽

Filial Obligation ◽

Satisfaction Scale ◽

Confirmatory Factor

Abstract The objective of this study was to translate and confirm the factor structure of the Familism Scale in the Brazilian Portuguese version. The sample included 716 Brazilian caregivers providing care to their own aging parents with Alzheimer’s Disease. The measures included the Familism Scale, the Filial Obligation Scale, the Life Satisfaction scale and the Center for Epidemiological Studies-Depression scale (CES-D). The questionnaire was individually filled online with use of the survey software package Qualtrics. Confirmatory Factor Analysis was used to examine the factor structure. The modified model demonstrated adequate fit (RMSEA = .063, CFI = .912). The hypotheses concerning convergence and divergence of validity from relevant variables were corroborated. These results support the use of the modified Familism Scale including twelve items and two factors with acceptable psychometric properties in a sample of Brazilian caregivers with Alzheimer’s Disease.

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