This chapter maps evidence-based interventions on the biopsychosocial model of causation suggested by the current evidence. Medications and biological treatments are still second-line interventions, which should be considered only if there is insufficient progress with psychological and social-familial treatments. There is very little progress in the past decade in testing medication interventions. New findings from neuroscience suggest another subtype of disruptive behavior disorders (DBDs), which holds considerable promise to improve outcomes in this treatment category. Psychological treatments are best supported by the evidence, especially when delivered in manualized form with a high degree of treatment fidelity. Familial and community-based interventions are also well supported, especially in complex, severe and chronic cases. There is a dearth of intervention studies targeting the different phenotypes of antisocial and aggressive behavior and studies of integrated treatment However, many studies are now available that approach treatment from a medical evidence–based rather than criminological perspective.
