The effect of cognitive behavioural therapy on the immune system of depressed patients

AbstractObjectiveAtypical features are common among depressed primary care patients, but clinical trials testing the efficacy of psychopharmacological and/or psychotherapeutic treatment are lacking. This paper examines the efficacy of sertraline and cognitive behavioural therapy (CBT) among depressed patients with atypical features.Subjects and methodsAnalyses involve a double-blind comparison of sertraline versus placebo (N = 47) and a single-blind comparison between CBT versus a guided self-help group (GSG) (N = 48), with primary efficacy endpoints being the Inventory of Depressive Symptomatology (IDSC) and Hamilton Depression Scale (HAMD-17).ResultsIn intent-to-treat (ITT) analyses, the decrease on the IDSC scale (and HAMD-17) was greater after CBT compared to GSG: p = 0.01 (HAMD-17: p = 0.01). The difference between selective serotonin reuptake inhibitors (SSRI) versus placebo was not significant: p = 0.22 (HAMD-17: p = 0.36).LimitationsThe number of cases in each treatment group was small, thereby limiting statistical power. Patients medicated with sertraline were 10 to 15 years younger than those included in the other groups of treatment.ConclusionsCBT may be an effective alternative to GSG for mildly depressed patients with atypical features. Although SSRI were not superior to placebo, it would be premature to rule out SSRI as efficacious in atypical depression.

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How do depressed patients experience cognitive behavioural therapy for insomnia?

Sleep Medicine ◽

10.1016/j.sleep.2017.11.245 ◽

2017 ◽

Vol 40 ◽

pp. e85

Author(s):

H. Dyrberg

Keyword(s):

Cognitive Behavioural Therapy ◽

Behavioural Therapy ◽

Depressed Patients ◽

Cognitive Behavioural ◽

Patients Experience

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Bridging science and religion – treatment of depressed Muslim patients using Islamic Integrated Cognitive Behavioural Therapy

Malaysian Journal of Science Health & Technology ◽

10.33102/mjosht.v6i.121 ◽

2021 ◽

Author(s):

Siti Nur Ainina Mohd Yusoff ◽

Amira Raudhah ◽

Nathratul Ayeshah Zulkifli ◽

Liyana Azmi

Keyword(s):

Mental Illness ◽

Cognitive Behavioural Therapy ◽

Health Problem ◽

Behavioural Therapy ◽

Science And Religion ◽

Mental Illnesses ◽

Depressed Patients ◽

Alternative Method ◽

Cognitive Behavioural ◽

Islamic Values

Mental illness, particularly depression, is an increasing health problem for many people from all walks of life. Both conventional and non-convventional therapies for mental illnesses including depression have been and are still being put to practice. An alternative method for treatment of depressed patients, particularly Muslims, is through the combination of Cognitive Behavioural Therapy with Islamic values, which is known as Islamic Integrated Cognitive Behavioural Therapy. This review discusses the benefits, limitations and future propects of Islamic Integrated Cognitive Behavioural Therapy particularly in treating Muslims with depression.

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