Molecular analysis of the unc-54 myosin heavy-chain gene of Caenorhabditis elegans

Nature ◽  
1981 ◽  
Vol 291 (5814) ◽  
pp. 386-390 ◽  
Author(s):  
Alexander R. MacLeod ◽  
Jonathan Karn ◽  
Sydney Brenner
Keyword(s):  
Caenorhabditis Elegans ◽  
Myosin Heavy Chain ◽  
Molecular Analysis ◽  
Heavy Chain ◽  
Chain Gene ◽  
Heavy Chain Gene ◽  
Myosin Heavy Chain Gene

Sequence analysis of the complete Caenorhabditis elegans myosin heavy chain gene family

1989 ◽  
Vol 205 (3) ◽  
pp. 603-613 ◽  
Author(s):  
Nick J. Dibb ◽  
Ichiro N. Maruyama ◽  
Michael Krause ◽  
Jonathan Karn
Keyword(s):  
Caenorhabditis Elegans ◽  
Sequence Analysis ◽  
Gene Family ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Chain Gene ◽  
Heavy Chain Gene ◽  
Myosin Heavy Chain Gene

Mutations in the unc-54 myosin heavy chain gene of caenorhabditis elegans that alter contractility but not muscle structure

Cell ◽  
1982 ◽  
Vol 29 (3) ◽  
pp. 773-781 ◽  
Author(s):  
Donald G. Moerman ◽  
Santiago Plurad ◽  
Robert H. Waterston ◽  
David L. Baillie
Keyword(s):  
Caenorhabditis Elegans ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Chain Gene ◽  
Heavy Chain Gene ◽  
Myosin Heavy Chain Gene ◽  
Muscle Structure

scholarly journals THE GENE STRUCTURES OF SPONTANEOUS MUTATIONS AFFECTING A CAENORHABDITIS ELEGANS MYOSIN HEAVY CHAIN GENE

Genetics ◽  
1985 ◽  
Vol 109 (1) ◽  
pp. 67-79
Author(s):  
David Eide ◽  
Philip Anderson
Keyword(s):  
Caenorhabditis Elegans ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Chain Gene ◽  
Spontaneous Mutations ◽  
Heavy Chain Gene ◽  
Myosin Heavy Chain Gene ◽  
Base Pairs ◽  
C Elegans ◽  
Gene Structures

ABSTRACT We have isolated spontaneous mutations affecting the unc-54 major myosin heavy chain gene of Caenorhabditis elegans (variety Bristol). Spontaneous unc-54 mutants occur in C. elegans populations at a frequency of approximately 3 × 10-7. We have studied the gene structure of 65 independent unc-54 mutations using filter-transfer hybridization techniques. Most unc-54 mutations (50 of 65) exhibit no abnormalities detected with these techniques; these mutations are small lesions affecting less than 100 base pairs. Approximately 17% of the mutations (11 of 65) are simple deletions, ranging in size from less than 100 base pairs to greater than 17 kilobases. One isolate contains two separate deletions, each of which affects unc-54. Two mutants contain tandem genetic duplications that include a portion of unc-54 and extend 8-10 kilobases beyond the 5' terminus of the mRNA. Conspicuously absent from our collection of spontaneous unc-54 mutations are any resulting from insertion of transposable genetic elements. Such mutants, if they occur, must arise at a frequency of less than 5 × 10-9

scholarly journals Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice.

1991 ◽  
Vol 266 (36) ◽  
pp. 24613-24620
Author(s):  
A. Subramaniam ◽  
W.K. Jones ◽  
J. Gulick ◽  
S. Wert ◽  
J. Neumann ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Gene Promoter ◽  
Chain Gene ◽  
Heavy Chain Gene ◽  
Myosin Heavy Chain Gene ◽  
Tissue Specific ◽  
Specific Regulation
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