Neuronal growth, atrophy and death in a sexually dimorphic song nucleus in the zebra finch brain

Nature ◽  
1985 ◽  
Vol 315 (6015) ◽  
pp. 145-147 ◽  
Author(s):  
Masakazu Konishi ◽  
Eugene Akutagawa
Keyword(s):  
Zebra Finch ◽  
Sexually Dimorphic ◽  
Neuronal Growth

Subcellular compartmentalization of aromatase is sexually dimorphic in the adult zebra finch brain

2007 ◽  
Vol 67 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Kevin N. Rohmann ◽  
Barney A. Schlinger ◽  
Colin J. Saldanha
Keyword(s):  
Zebra Finch ◽  
Sexually Dimorphic ◽  
Subcellular Compartmentalization

Subcellular compartmentalization of aromatase is sexually dimorphic in the adult zebra finch brain

2006 ◽  
Vol 67 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Kevin N. Rohmann ◽  
Barney A. Schlinger ◽  
Colin J. Saldanha
Keyword(s):  
Zebra Finch ◽  
Sexually Dimorphic ◽  
Subcellular Compartmentalization

Sexually dimorphic neurocalcin expression in the developing zebra finch telencephalon

2003 ◽  
Vol 56 (4) ◽  
pp. 372-386 ◽  
Author(s):  
Sean L. Veney ◽  
Camilla Peabody ◽  
George W. Smith ◽  
Juli Wade
Keyword(s):  
Zebra Finch ◽  
Sexually Dimorphic

scholarly journals DNA Methylation Regulates Transcription Factor-Specific Neurodevelopmental but Not Sexually Dimorphic Gene Expression Dynamics in Zebra Finch Telencephalon

2021 ◽  
Vol 9 ◽  
Author(s):  
Jolien Diddens ◽  
Louis Coussement ◽  
Carolina Frankl-Vilches ◽  
Gaurav Majumdar ◽  
Sandra Steyaert ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Transcription Factor ◽  
Zebra Finch ◽  
Dosage Compensation ◽  
Expression Patterns ◽  
Song Learning ◽  
Sexually Dimorphic ◽  
Gene Expression Dynamics ◽  
Dimorphic Gene Expression

Song learning in zebra finches (Taeniopygia guttata) is a prototypical example of a complex learned behavior, yet knowledge of the underlying molecular processes is limited. Therefore, we characterized transcriptomic (RNA-sequencing) and epigenomic (RRBS, reduced representation bisulfite sequencing; immunofluorescence) dynamics in matched zebra finch telencephalon samples of both sexes from 1 day post hatching (1 dph) to adulthood, spanning the critical period for song learning (20 and 65 dph). We identified extensive transcriptional neurodevelopmental changes during postnatal telencephalon development. DNA methylation was very low, yet increased over time, particularly in song control nuclei. Only a small fraction of the massive differential expression in the developing zebra finch telencephalon could be explained by differential CpG and CpH DNA methylation. However, a strong association between DNA methylation and age-dependent gene expression was found for various transcription factors (i.e., OTX2, AR, and FOS) involved in neurodevelopment. Incomplete dosage compensation, independent of DNA methylation, was found to be largely responsible for sexually dimorphic gene expression, with dosage compensation increasing throughout life. In conclusion, our results indicate that DNA methylation regulates neurodevelopmental gene expression dynamics through steering transcription factor activity, but does not explain sexually dimorphic gene expression patterns in zebra finch telencephalon.

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