Sexually dimorphic neurocalcin expression in the developing zebra finch telencephalon

2003 ◽  
Vol 56 (4) ◽  
pp. 372-386 ◽  
Author(s):  
Sean L. Veney ◽  
Camilla Peabody ◽  
George W. Smith ◽  
Juli Wade
Keyword(s):  
Zebra Finch ◽  
Sexually Dimorphic

Neuronal growth, atrophy and death in a sexually dimorphic song nucleus in the zebra finch brain

Nature ◽  
1985 ◽  
Vol 315 (6015) ◽  
pp. 145-147 ◽  
Author(s):  
Masakazu Konishi ◽  
Eugene Akutagawa
Keyword(s):  
Zebra Finch ◽  
Sexually Dimorphic ◽  
Neuronal Growth

Subcellular compartmentalization of aromatase is sexually dimorphic in the adult zebra finch brain

2007 ◽  
Vol 67 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Kevin N. Rohmann ◽  
Barney A. Schlinger ◽  
Colin J. Saldanha
Keyword(s):  
Zebra Finch ◽  
Sexually Dimorphic ◽  
Subcellular Compartmentalization

Subcellular compartmentalization of aromatase is sexually dimorphic in the adult zebra finch brain

2006 ◽  
Vol 67 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Kevin N. Rohmann ◽  
Barney A. Schlinger ◽  
Colin J. Saldanha
Keyword(s):  
Zebra Finch ◽  
Sexually Dimorphic ◽  
Subcellular Compartmentalization

scholarly journals DNA Methylation Regulates Transcription Factor-Specific Neurodevelopmental but Not Sexually Dimorphic Gene Expression Dynamics in Zebra Finch Telencephalon

2021 ◽  
Vol 9 ◽  
Author(s):  
Jolien Diddens ◽  
Louis Coussement ◽  
Carolina Frankl-Vilches ◽  
Gaurav Majumdar ◽  
Sandra Steyaert ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Transcription Factor ◽  
Zebra Finch ◽  
Dosage Compensation ◽  
Expression Patterns ◽  
Song Learning ◽  
Sexually Dimorphic ◽  
Gene Expression Dynamics ◽  
Dimorphic Gene Expression

Song learning in zebra finches (Taeniopygia guttata) is a prototypical example of a complex learned behavior, yet knowledge of the underlying molecular processes is limited. Therefore, we characterized transcriptomic (RNA-sequencing) and epigenomic (RRBS, reduced representation bisulfite sequencing; immunofluorescence) dynamics in matched zebra finch telencephalon samples of both sexes from 1 day post hatching (1 dph) to adulthood, spanning the critical period for song learning (20 and 65 dph). We identified extensive transcriptional neurodevelopmental changes during postnatal telencephalon development. DNA methylation was very low, yet increased over time, particularly in song control nuclei. Only a small fraction of the massive differential expression in the developing zebra finch telencephalon could be explained by differential CpG and CpH DNA methylation. However, a strong association between DNA methylation and age-dependent gene expression was found for various transcription factors (i.e., OTX2, AR, and FOS) involved in neurodevelopment. Incomplete dosage compensation, independent of DNA methylation, was found to be largely responsible for sexually dimorphic gene expression, with dosage compensation increasing throughout life. In conclusion, our results indicate that DNA methylation regulates neurodevelopmental gene expression dynamics through steering transcription factor activity, but does not explain sexually dimorphic gene expression patterns in zebra finch telencephalon.

scholarly journals Using Digital Images of the Zebra Finch Song System as a Tool to Teach Organizational Effects of Steroid Hormones: A Free Downloadable Module

2011 ◽  
Vol 10 (2) ◽  
pp. 222-230
Author(s):  
William Grisham ◽  
Natalie A. Schottler ◽  
Lisa M. Beck McCauley ◽  
Anh P. Pham ◽  
Maureen L. Ruiz ◽  
...  
Keyword(s):  
Steroid Hormones ◽  
Zebra Finch ◽  
Neural System ◽  
Experimental Manipulation ◽  
Digital Tools ◽  
Free Access ◽  
Developmental Study ◽  
Sexually Dimorphic ◽  
Song System ◽  
Zebra Finch Song

Zebra finch song behavior is sexually dimorphic: males sing and females do not. The neural system underlying this behavior is sexually dimorphic, and this sex difference is easy to quantify. During development, the zebra finch song system can be altered by steroid hormones, specifically estradiol, which actually masculinizes it. Because of the ease of quantification and experimental manipulation, the zebra finch song system has great potential for use in undergraduate labs. Unfortunately, the underlying costs prohibit use of this system in undergraduate labs. Further, the time required to perform a developmental study renders such undertakings unrealistic within a single academic term. We have overcome these barriers by creating digital tools, including an image library of song nuclei from zebra finch brains. Students using this library replicate and extend a published experiment examining the dose of estradiol required to masculinize the female zebra finch brain. We have used this library for several terms, and students not only obtain significant experimental results but also make gains in understanding content, experimental controls, and inferential statistics (analysis of variance and post hoc tests). We have provided free access to these digital tools at the following website: http://mdcune.psych.ucla.edu/modules/birdsong .

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