Inflammatory Bowel Disease Patients’ Willingness to Accept Medication Risk to Avoid Future Disease Relapse

2015 ◽  
Vol 110 (12) ◽  
pp. 1675-1681 ◽  
Author(s):  
Meenakshi Bewtra ◽  
Angelyn O Fairchild ◽  
Erin Gilroy ◽  
David A Leiman ◽  
Caroline Kerner ◽  
...  
2015 ◽  
Vol 61 (4) ◽  
pp. 1013-1020 ◽  
Author(s):  
Alexandra Feathers ◽  
Tommy Yen ◽  
Laura Yun ◽  
Garrett Strizich ◽  
Arun Swaminath

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Manoj Kumar ◽  
Mathieu Garand ◽  
Souhaila Al Khodor

Abstract Background Inflammatory Bowel Disease (IBD) is a multifactorial chronic disease. Understanding only one aspect of IBD pathogenesis does not reflect the complex nature of IBD nor will it improve its clinical management. Therefore, it is vital to dissect the interactions between the different players in IBD pathogenesis in order to understand the biology of the disease and enhance its clinical outcomes. Aims To provide an overview of the available omics data used to assess the potential mechanisms through which various players are contributing to IBD pathogenesis and propose a precision medicine model to fill the current knowledge gap in IBD. Results Several studies have reported microbial dysbiosis, immune and metabolic dysregulation in IBD patients, however, this data is not sufficient to create signatures that can differentiate between the disease subtypes or between disease relapse and remission. Conclusions We summarized the current knowledge in the application of omics in IBD patients, and we showed that the current knowledge gap in IBD hinders the improvements of clinical decision for treatment as well as the prediction of disease relapse. We propose one way to fill this gap by implementing integrative analysis of various omics datasets generated from one patient at a single time point.


2019 ◽  
Vol 17 (6) ◽  
pp. 24-27
Author(s):  
Palle Bager ◽  
Susanna Jäghult

Adherence to treatment can be challenging, especially in chronic diseases. In inflammatory bowel disease (IBD), maintenance therapy is common to prevent a disease relapse, and adherence becomes even more of a challenge during remission. Furthermore, practical problems with taking topical treatment can increase the likelihood of non-adherence. In IBD, the definition adherence can be expanded beyond taking medication to factors like leaving blood or stool samples, keeping appointments or adjusting behaviour regarding smoking or diet. This review provides a taxonomy of different types of non-adherence and indicates how these types call for different interventions. Furthermore, the article describes how IBD nurses can open up conversations with patients that will hopefully lead to improvements in their adherence.


PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e84957
Author(s):  
Tiago Nunes ◽  
Maria Josefina Etchevers ◽  
Maria Jose Sandi ◽  
Susana Pinó Donnay ◽  
Teddy Grandjean ◽  
...  

Author(s):  
Tatyana Kushner ◽  
Angelyn Fairchild ◽  
F. Reed Johnson ◽  
Bruce E. Sands ◽  
Uma Mahadevan ◽  
...  

2011 ◽  
Vol 140 (5) ◽  
pp. S-446
Author(s):  
Maria Josefina Etchevers ◽  
Tiago Nunes ◽  
Susana P. Donnay ◽  
Teddy Grandjean ◽  
Maria Pellise ◽  
...  

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