ANT-UNet: Accurate and Noise-Tolerant Segmentation for Pathology Image Processing

Pathology image segmentation is an essential step in early detection and diagnosis for various diseases. Due to its complex nature, precise segmentation is not a trivial task. Recently, deep learning has been proved as an effective option for pathology image processing. However, its efficiency is highly restricted by inconsistent annotation quality. In this article, we propose an accurate and noise-tolerant segmentation approach to overcome the aforementioned issues. This approach consists of two main parts: a preprocessing module for data augmentation and a new neural network architecture, ANT-UNet. Experimental results demonstrate that, even on a noisy dataset, the proposed approach can achieve more accurate segmentation with 6% to 35% accuracy improvement versus other commonly used segmentation methods. In addition, the proposed architecture is hardware friendly, which can reduce the amount of parameters to one-tenth of the original and achieve 1.7× speed-up.

Arabic open information extraction system using dependency parsing

<p>Arabic is a Semitic language and one of the most natural languages distinguished by the richness in morphological enunciation and derivation. This special and complex nature makes extracting information from the Arabic language difficult and always needs improvement. Open information extraction systems (OIE) have been emerged and used in different languages, especially in English. However, it has almost not been used for the Arabic language. Accordingly, this paper aims to introduce an OIE system that extracts the relation tuple from Arabic web text, exploiting Arabic dependency parsing and thinking carefully about all possible text relations. Based on clause types' propositions as extractable relations and constituents' grammatical functions, the identities of corresponding clause types are established. The proposed system named Arabic open information extraction(AOIE) can extract highly scalable Arabic text relations while being domain independent. Implementing the proposed system handles the problem using supervised strategies while the system relies on unsupervised extraction strategies. Also, the system has been implemented in several domains to avoid information extraction in a specific field. The results prove that the system achieves high efficiency in extracting clauses from large amounts of text.</p>

History of the Study of Imitative in General Linguistics

The history of the origin of imitative has ancient roots. People have been interested in imitations since ancient times. Not only linguists, but also even philosophers, psychologists, to one degree or another at different times, have addressed the problem of sound visualization. Imitative vocabulary helps to increase the imagery and emotional expressiveness of the word. However, due to its complex nature, for some time, linguists of various languages did not conduct serious research on the linguistic functions of imitative words. However, they are often found in oral folk art and fiction, giving these texts artistic and poetic meaning, expressiveness, imagery, artistic power and accessibility, liveliness and dynamism, all this has led, now, to the fact that linguists began to pay close attention the study of this unusual group of words. Тhey are divided into types, separated into a special part of speech, they are used in the formation of new words, they act as members of a sentence.

Developing a Scale of Care Work-Related Quality of Life (CWRQoL) for Long-Term Care Workers in England

Background: Long-term care (LTC) workers are subjected to structural and inherent difficult conditions that are likely to impact their quality of life at work; however, no agreed scale measures it. This study aims to develop a scale to measure the work-related quality of life among LTC workers in England (CWRQoL). The study establishes the domains/sub-domains of CWRQoL, investigates the tool’s utility and collates information on existing supporting strategies for CWRQoL. Methods: We adopt a mixed-methods approach employing inductive/deductive processes at three stages: (1) a scoping review of the literature; (2) interviews and focus groups with frontline LTC workers, managers and LTC stakeholders; and (3) a content validity consensus survey. Results: CWRQoL is composed of seven domains (and 23 sub-domains). Additional domains to those in the literature include financial wellbeing, sufficient time for building relations, managing grief and emotions associated with client death and end of life care. Stakeholders identified several benefits and challenges related to the CWRQoL tool’s utility. COVID-19 significantly impacted LTC workers’ mental wellbeing and spillover between work and home. Conclusions: The study highlighted the complex nature of CWRQoL and provided a solid ground for developing and validating a CWRQoL scale.

Beyond the “Third Wave of Positive Psychology”: Challenges and Opportunities for Future Research

The positive psychology (PP) landscape is changing, and its initial identity is being challenged. Moving beyond the “third wave of PP,” two roads for future research and practice in well-being studies are discerned: The first is the state of the art PP trajectory that will (for the near future) continue as a scientific (sub)discipline in/next to psychology (because of its popular brand name). The second trajectory (main focus of this manuscript) links to pointers described as part of the so-called third wave of PP, which will be argued as actually being the beginning of a new domain of inter- or transdisciplinary well-being studies in its own right. It has a broader scope than the state of the art in PP, but is more delineated than in planetary well-being studies. It is in particular suitable to understand the complex nature of bio-psycho-social-ecological well-being, and to promote health and wellness in times of enormous challenges and changes. A unique cohering focus for this post-disciplinary well-being research domain is proposed. In both trajectories, future research will have to increase cognizance of metatheoretical assumptions, develop more encompassing theories to bridge the conceptual fragmentation in the field, and implement methodological reforms, while keeping context and the interwovenness of the various levels of the scientific text in mind. Opportunities are indicated to contribute to the discourse on the identity and development of scientific knowledge in mainstream positive psychology and the evolving post-disciplinary domain of well-being studies.

Rational design yields molecular insights on leaf binding of the anchor peptide Macaque Histatin

In times of a constantly growing world population and increasing demand for food, sustainable agriculture is crucial. To reduce the amount of applied nutrients, herbicides, and fungicides, the rainfastness of plant protection agents is of pivotal importance. As a result of protective agent wash-off, plant protection is lost, and soils and groundwater are severely polluted. To date, rainfastness of plant protection products is achieved by adding polymeric adjuvants to the agrochemicals. However, polymeric adjuvants will be regarded as microplastics in the future, and environmentally friendly alternatives are needed. Anchor peptides (APs) are promising biobased and biodegradable adhesion promoters. While the adhesion of anchor peptides to artificial surfaces, such as polymers, has already been investigated in theory and experimentally, exploiting the adhesion to biological surfaces remains challenging. The complex nature and composition of biological surfaces such as plant leaf and fruit surfaces complicate the generation of accurate models. Here, we present the first detailed three-layered atomistic model of the surface of apple leaves and use it to compute free energy profiles of the adhesion and desorption of APs to and from that surface. Our model is validated by a novel fluorescence-based MTP assay that mimicks these complex processes and allows quantifying them. For the AP Macaque Histatin, we demonstrate that aromatic and positively charged amino acids are essential for binding to the waxy apple leaf surface. The established protocols should generally be applicable for tailoring the binding properties of APs to biological interfaces.

The Selection, Promotion, and Reception of Translated Fiction in Wellington

<p>This is the first systematic study of the selection, promotion, and reception of translated fiction anywhere in New Zealand. The study has two phases. The first draws on the responses of 277 adult readers in Wellington to a questionnaire about their perceptions of translated fiction. The findings reveal that most Wellington readers say they enjoy reading books set in other cultures, but their actual reading is largely English-language oriented. While some respondents expressed a specific interest in reading translated fiction, most prioritised genre and content. Age and ethnicity correlate only weakly with perceptions of translated fiction, but knowledge of one or more second languages is a strong predictor of positive perceptions of translated fiction. The second phase of the study draws on seven semi-structured interviews with representatives from three major book-related entities in Wellington: New Zealand Festival’s Writers Week, Wellington City Libraries (WCL), and Unity Books. The interviews provided first-hand insights into each entity’s policies and practices for selecting and promoting translated fiction. Although its past and current coordinators speak highly of translated literature, Wellington’s Writers Week has seen a significant decline in the number of non-English-speaking writers in the last two decades. Similarly, Unity Books claims to treat all categories of books, including translated fiction, equally, but its commercial practice in fact prioritises certain other categories. Wellington City Libraries, on the other hand, has taken a proactive approach to the promotion of translated fiction, for example through blogs and physical displays. Combined with the survey data, the interview findings demonstrate both the complex nature of reading choices and the challenges of advocating for the enhanced visibility of translated fiction in a largely monolingual context. However, many signs also point to a growing recognition of translated fiction as an important element of eclectic reading. This recognition can lead to positive changes in the future.</p>

The Selection, Promotion, and Reception of Translated Fiction in Wellington

<p>This is the first systematic study of the selection, promotion, and reception of translated fiction anywhere in New Zealand. The study has two phases. The first draws on the responses of 277 adult readers in Wellington to a questionnaire about their perceptions of translated fiction. The findings reveal that most Wellington readers say they enjoy reading books set in other cultures, but their actual reading is largely English-language oriented. While some respondents expressed a specific interest in reading translated fiction, most prioritised genre and content. Age and ethnicity correlate only weakly with perceptions of translated fiction, but knowledge of one or more second languages is a strong predictor of positive perceptions of translated fiction. The second phase of the study draws on seven semi-structured interviews with representatives from three major book-related entities in Wellington: New Zealand Festival’s Writers Week, Wellington City Libraries (WCL), and Unity Books. The interviews provided first-hand insights into each entity’s policies and practices for selecting and promoting translated fiction. Although its past and current coordinators speak highly of translated literature, Wellington’s Writers Week has seen a significant decline in the number of non-English-speaking writers in the last two decades. Similarly, Unity Books claims to treat all categories of books, including translated fiction, equally, but its commercial practice in fact prioritises certain other categories. Wellington City Libraries, on the other hand, has taken a proactive approach to the promotion of translated fiction, for example through blogs and physical displays. Combined with the survey data, the interview findings demonstrate both the complex nature of reading choices and the challenges of advocating for the enhanced visibility of translated fiction in a largely monolingual context. However, many signs also point to a growing recognition of translated fiction as an important element of eclectic reading. This recognition can lead to positive changes in the future.</p>

Change by Activism: Insurgency, Autonomy, and Political Activism in Potosí-Jerusalén, Bogotá, Colombia

Cities today face a context in which traditional politics and policies struggle to cope with increasing urbanisation rates and growing inequalities. Meanwhile, social movements and political activists are rising up and inhabiting urban spaces as sites of contestation. However, through their practices, urban activists do more than just occupy spaces; they are fundamental drivers of urban transformation as they constantly face—and contest—spatial manifestations of power. This article aims to contribute to ongoing discussions on the role of activism in the field of urban design, by engaging with two concepts coming from the Global South: <em>insurgency</em> and <em>autonomy</em>. Through a historical account of the building of the Potosí-Jerusalén neighbourhood in Bogotá in the 1980s, it illustrates how both concepts can provide new insight into urban change by activism. On the one hand, the concept of insurgency helps unpack a mode of bottom-up action that inaugurates political spaces of contestation with the state; autonomy, on the other hand, helps reveal the complex nature of political action and the visions of urban transformation it entails. Although they were developed at the margins of conventional design theory and practice, both concepts are instrumental in advancing our understanding of how cities are shaped by activist practices. Thus, this article is part of a broader effort to (re)locate political activism in discussions about urban transformation, and rethink activism as a form of urban design practice.

A new fuzzy multi-criteria decision-making approach for risk assessment of competitors’ cooperation in new product development projects

Purpose This study aims to identify and accurately assess the risk factors of competitors’ cooperation in the NPD project. Design/methodology/approach New product development (NPD) is essential to the survival of companies and surpassing other competitors. A key prerequisite for the success of an NPD project is the timing of new product delivery to the market. The main challenge faced by many project managers is the delay in execution and completion phases due to the complex nature and uncertainty of these projects. Rival companies' cooperation reduces the time spent on an NPD project which is an excellent way to reduce the risk of losing the market, but it increases other risk factors. Findings Based on the results, the security and confidentiality of innovation, the competitors attracting human resources and the company’s brand credibility factors were ranked higher than other factors and should be predicted and managed before cooperating with competitors. Originality/value This paper proposed a new model to assess risk factors in cooperation with rival companies in NPD projects. This model takes into account new parameters, for example, negative and positive risks, negative and positive passable risks and risk-based multi-objective optimization by ratio analysis plus full multiplicative form methodology for the rival companies cooperation in NPD projects. To evaluate the efficiency of the proposed model, a real case of the R&D unit of Iran Khodro Company was studied.