scholarly journals Vindesine receptors in cells of a human leukaemia cell line

1982 ◽  
Vol 46 (3) ◽  
pp. 392-396 ◽  
Author(s):  
K Totsuka ◽  
K Oshimi ◽  
H Mizoguchi
Keyword(s):  
Cell Line ◽  
Leukaemia Cell ◽  
Leukaemia Cell Line ◽  
Human Leukaemia Cell ◽  
Human Leukaemia ◽  
In Cells

Induction of erythroid differentiation in the human leukaemia cell line K562

Nature ◽  
1979 ◽  
Vol 278 (5702) ◽  
pp. 364-365 ◽  
Author(s):  
LEIF C. ANDERSSON ◽  
MIKKO JOKINEN ◽  
CARL G. GAHMBERG
Keyword(s):  
Cell Line ◽  
Erythroid Differentiation ◽  
Leukaemia Cell ◽  
Leukaemia Cell Line ◽  
Human Leukaemia Cell ◽  
Human Leukaemia

Expression of multidrug resistance in response to differentiation in the K562 human leukaemia cell line

1995 ◽  
Vol 50 (4) ◽  
pp. 475-480 ◽  
Author(s):  
Denese C. Marks ◽  
Mary W. Davey ◽  
Ross A. Davey ◽  
Antony D. Kidman
Keyword(s):  
Multidrug Resistance ◽  
Cell Line ◽  
Leukaemia Cell ◽  
Leukaemia Cell Line ◽  
Human Leukaemia Cell ◽  
Human Leukaemia

Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line

Nature ◽  
1983 ◽  
Vol 306 (5942) ◽  
pp. 494-497 ◽  
Author(s):  
Peter Nowell ◽  
Janet Finan ◽  
Riccardo Dalla Favera ◽  
Robert C. Gallo ◽  
Abbas ar-Rushdi ◽  
...  
Keyword(s):  
Cell Line ◽  
Chromosome 8 ◽  
Leukaemia Cell ◽  
Leukaemia Cell Line ◽  
Human Leukaemia Cell ◽  
Human Leukaemia

scholarly journals Quantitative structure-activity relationship (QSAR) investigation on 2-arylideneaminobenzimidazole derivatives as anti-proliferative activity against mv4-11 human leukaemia cells

2019 ◽  
Vol 9 (2) ◽  
pp. 95-101 ◽  
Author(s):  
Wisam Abdalhassan Radhi ◽  
Sadiq Hasan Ismael ◽  
Jasim Mohammad Alshawi ◽  
Kawkab Ali Hussain
Keyword(s):  
Cell Line ◽  
Proliferative Activity ◽  
Quantitative Structure Activity Relationship ◽  
Basis Set ◽  
Empirical Theory ◽  
Leukaemia Cell ◽  
Leukaemia Cell Line ◽  
Semi Empirical ◽  
Human Leukaemia Cell ◽  
Human Leukaemia

This undertaking involves QSAR investigations on the use of 28 2-arylideneaminobenzimidazole derivatives, for curbing the proliferative activity of cells in the mv4-11 human leukaemia cell line. The geometries of the compounds under investigation were initially optimized at level (PM3) in accordance to the semi-empirical theory, and subsequently through the B3LYP procedure at the 6-31G(d) basis set in accordance to the DFT theory. The multiple regression procedure was employed for the construction of two QSAR equations, to assess the anti-proliferative activity of these compounds (Equations 1 and 2). The values of R2 extended from 0.792 to 0.812, those of S from 0.187 to 0.193, and those of F from 24.897 to 30.429. According to the results attained, the use of four parameters in Equation 2[(N5), (N10), r(C1=N2) andLUMO+4] led to raised R2 values and minimized S values. This suggests that these parameters are significant for identifying the anti-proliferative effectiveness of the compounds, in the context of mv4-11 human leukaemia cell line cells. This revelation is also an indication that QSAR can be successfully applied for a broad range of compounds. 

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