scholarly journals Phosphorus-31 metabolism of post-menopausal breast cancer studied in vivo by magnetic resonance spectroscopy

1994 ◽  
Vol 69 (6) ◽  
pp. 1151-1156 ◽  
Author(s):  
CJ Twelves ◽  
DA Porter ◽  
M Lowry ◽  
NA Dobbs ◽  
PE Graves ◽  
...  
2020 ◽  
Vol 6 (1) ◽  
pp. 20190090 ◽  
Author(s):  
Almir G.V. Bitencourt ◽  
Katja Pinker ◽  
Sunitha Thakur

Magnetic resonance spectroscopy (MRS) is a promising non-invasive diagnostic method that can detect and quantify endogenous tissue metabolites. High glycine levels obtained from ex vivo breast MRS have been associated with poor prognosis; however, glycine evaluation has not been reported regarding in vivo MRS. We report our finding in a breast cancer patient in whom pre-treatment but not post-treatment in vivo MRS showed elevated glycine and discuss the implications of this finding.


This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.


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